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The map label for this gene is appC [H]

Identifier: 167625631

GI number: 167625631

Start: 4523070

End: 4523894

Strand: Reverse

Name: appC [H]

Synonym: Shal_3726

Alternate gene names: 167625631

Gene position: 4523894-4523070 (Counterclockwise)

Preceding gene: 167625632

Following gene: 167625630

Centisome position: 86.55

GC content: 52.97

Gene sequence:

>825_bases
ATGCATAGCACACTGCGCCAGCCGACATTTATTTTAGCATCCGCCTGCTTACTGCTGTTGGTACTGACCGCCTTTTTATG
GCCATTTCAGGGGGCAGAACTCAATCTGCTGCATAAGTATCAAGCTCCCTCTATGGCGTATTTTTTTGGTACCGATTGGT
TAGGGCGAGATCTGTTTAGTCGTAGCTTACAAGCGCTGGCCCAGAGCATCTATGTGGGGGGGCTCGCGGTGCTGATGAGT
AGTCTCTTAGCGCTGATGATGGCGATGTTCGCCATGCTGCATCCATACTGCCGTTGGCTGGTGGACTTGCTCGTGGATCT
GTTTATGTCGCTGCCGCATCTGCTGCTACTGATCTTGCTCTCTTTGGCCTTTGGTGGGGCCGAGTGGGGCTTAGTGATTG
CCATAGCACTGAGCCACTGGCCCAAGCTTACGCGGCTATTGCGCTTTGAGATGCAGCAAGTGCAGTCGACTCCCTATTAT
CAGTTAGCCTGTCAGTTTGGTCGCTCCCCGTGGCAACGGCTTAAAACCCATATGTTGCCACATATTCTGCCTCAGTGGTG
GATAGGAGGCTTGCTCCTGTTTCCCCACGCCTTGACTCATATGGCTGCCTTAACCTTTTTGGGCTTTGGCTTAAATCCAG
ATAGCCCGTCTATGGGAGCCCTGCTCGCTCAAGCGAGCCAATATGTACTTACCGGACATTGGTGGCTGGGTGTGTGCCCT
GGGTTGTTACTGCTTATCTGCTTACTGCTGCTGTCTTATATTGCCCAGCAGTTATTGGCGGCGCTGCGCCAGGGGCCGCA
GACCCATCTTAAAGGAGCTGTGTAA

Upstream 100 bases:

>100_bases
CGAGTGATGCATAAAAGCTACTGCGTCAGCTCAGCTCTCTTTCGGAGATGCAAAATGCGCAATATGTCGCGCCAGCCGAT
ATGTATGCAGGAGGCGAAAG

Downstream 100 bases:

>100_bases
TGTTGTGTGTCGATAAACTCAGTATTCAATCGAGTGACATCTGCTTGTTATCCCCCTTAAGTTTCTCGATTGCTAAGGGC
GAAGTATTCGGTGTGGTAGG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MHSTLRQPTFILASACLLLLVLTAFLWPFQGAELNLLHKYQAPSMAYFFGTDWLGRDLFSRSLQALAQSIYVGGLAVLMS
SLLALMMAMFAMLHPYCRWLVDLLVDLFMSLPHLLLLILLSLAFGGAEWGLVIAIALSHWPKLTRLLRFEMQQVQSTPYY
QLACQFGRSPWQRLKTHMLPHILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDSPSMGALLAQASQYVLTGHWWLGVCP
GLLLLICLLLLSYIAQQLLAALRQGPQTHLKGAV

Sequences:

>Translated_274_residues
MHSTLRQPTFILASACLLLLVLTAFLWPFQGAELNLLHKYQAPSMAYFFGTDWLGRDLFSRSLQALAQSIYVGGLAVLMS
SLLALMMAMFAMLHPYCRWLVDLLVDLFMSLPHLLLLILLSLAFGGAEWGLVIAIALSHWPKLTRLLRFEMQQVQSTPYY
QLACQFGRSPWQRLKTHMLPHILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDSPSMGALLAQASQYVLTGHWWLGVCP
GLLLLICLLLLSYIAQQLLAALRQGPQTHLKGAV
>Mature_274_residues
MHSTLRQPTFILASACLLLLVLTAFLWPFQGAELNLLHKYQAPSMAYFFGTDWLGRDLFSRSLQALAQSIYVGGLAVLMS
SLLALMMAMFAMLHPYCRWLVDLLVDLFMSLPHLLLLILLSLAFGGAEWGLVIAIALSHWPKLTRLLRFEMQQVQSTPYY
QLACQFGRSPWQRLKTHMLPHILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDSPSMGALLAQASQYVLTGHWWLGVCP
GLLLLICLLLLSYIAQQLLAALRQGPQTHLKGAV

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=232, Percent_Identity=31.0344827586207, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787054, Length=266, Percent_Identity=25.9398496240602, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788505, Length=228, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789889, Length=247, Percent_Identity=24.6963562753036, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789964, Length=226, Percent_Identity=29.646017699115, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787549, Length=227, Percent_Identity=25.9911894273128, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30678; Mature: 30678

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSTLRQPTFILASACLLLLVLTAFLWPFQGAELNLLHKYQAPSMAYFFGTDWLGRDLFS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEHHHCCHHHHHHHHH
RSLQALAQSIYVGGLAVLMSSLLALMMAMFAMLHPYCRWLVDLLVDLFMSLPHLLLLILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAFGGAEWGLVIAIALSHWPKLTRLLRFEMQQVQSTPYYQLACQFGRSPWQRLKTHMLP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
HILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDSPSMGALLAQASQYVLTGHWWLGVCP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
GLLLLICLLLLSYIAQQLLAALRQGPQTHLKGAV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MHSTLRQPTFILASACLLLLVLTAFLWPFQGAELNLLHKYQAPSMAYFFGTDWLGRDLFS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEHHHCCHHHHHHHHH
RSLQALAQSIYVGGLAVLMSSLLALMMAMFAMLHPYCRWLVDLLVDLFMSLPHLLLLILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAFGGAEWGLVIAIALSHWPKLTRLLRFEMQQVQSTPYYQLACQFGRSPWQRLKTHMLP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
HILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDSPSMGALLAQASQYVLTGHWWLGVCP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
GLLLLICLLLLSYIAQQLLAALRQGPQTHLKGAV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]