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The map label for this gene is dppD [H]

Identifier: 167625630

GI number: 167625630

Start: 4522363

End: 4523070

Strand: Reverse

Name: dppD [H]

Synonym: Shal_3725

Alternate gene names: 167625630

Gene position: 4523070-4522363 (Counterclockwise)

Preceding gene: 167625631

Following gene: 167625629

Centisome position: 86.53

GC content: 53.81

Gene sequence:

>708_bases
ATGTTGTGTGTCGATAAACTCAGTATTCAATCGAGTGACATCTGCTTGTTATCCCCCTTAAGTTTCTCGATTGCTAAGGG
CGAAGTATTCGGTGTGGTAGGAGCGAGCGGTAGCGGCAAGAGCCTATTAGCGCAGGCTCTATTAGGCCAAGTGCCGGACG
GGTTTAACTTAAGTGGTCAGGTGCTCCATCGCAGTGGTGATAGGCGAGTATTGGCGGCCCAGTCAGCTTCGGTGCTCGAC
CCTTTAAGGCGGATTTCATCGCAATTAAGTTATGCCTTGAGCCGAGTGCCTAAGGGCGCGACACGCAAGAGGCGTTTCCC
GCTGGCGGCAGATATTACGCGTTGTTATCGCCATCAGCTGTCTGGTGGCATGGCTAAACGGGCATTACTGGCTCAGGCCT
GTTGGCAGGCCAGTGAAATCATGATTGCCGATGAGCCATGCTGCGGCCTAGATACACAGGCCGCCGAGGCGATCTATCAA
CACCTCGCTTACTTGGCTCAAAGTGAGGACGTTGCTGTGATGGTGATAAGTCATAACCTAAGGCAGTTGCTTACGGTGGC
CGACCGCATCTTGGTGCTGCGCGATGGCAAGCTGGTTGAGATCACCACAGCTGCCAATATTCGTAACGGCACCTGCGACA
GCTATACACAAAGTCTGTGGGCGGCTCTGCCTGAGCACTGGGGGCTAACAAATGCTAACGCTGCGTAA

Upstream 100 bases:

>100_bases
TGTTACTGCTTATCTGCTTACTGCTGCTGTCTTATATTGCCCAGCAGTTATTGGCGGCGCTGCGCCAGGGGCCGCAGACC
CATCTTAAAGGAGCTGTGTA

Downstream 100 bases:

>100_bases
TGGTTATCTACACCGTCGCAATAAGAGGATTGAATTTCCCGATATCTATTTGCCGCGGGGTGAGGTATTGGGGATCTCTG
GTCCCAGCGGTGTAGGTAAG

Product: ABC transporter-like protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLCVDKLSIQSSDICLLSPLSFSIAKGEVFGVVGASGSGKSLLAQALLGQVPDGFNLSGQVLHRSGDRRVLAAQSASVLD
PLRRISSQLSYALSRVPKGATRKRRFPLAADITRCYRHQLSGGMAKRALLAQACWQASEIMIADEPCCGLDTQAAEAIYQ
HLAYLAQSEDVAVMVISHNLRQLLTVADRILVLRDGKLVEITTAANIRNGTCDSYTQSLWAALPEHWGLTNANAA

Sequences:

>Translated_235_residues
MLCVDKLSIQSSDICLLSPLSFSIAKGEVFGVVGASGSGKSLLAQALLGQVPDGFNLSGQVLHRSGDRRVLAAQSASVLD
PLRRISSQLSYALSRVPKGATRKRRFPLAADITRCYRHQLSGGMAKRALLAQACWQASEIMIADEPCCGLDTQAAEAIYQ
HLAYLAQSEDVAVMVISHNLRQLLTVADRILVLRDGKLVEITTAANIRNGTCDSYTQSLWAALPEHWGLTNANAA
>Mature_235_residues
MLCVDKLSIQSSDICLLSPLSFSIAKGEVFGVVGASGSGKSLLAQALLGQVPDGFNLSGQVLHRSGDRRVLAAQSASVLD
PLRRISSQLSYALSRVPKGATRKRRFPLAADITRCYRHQLSGGMAKRALLAQACWQASEIMIADEPCCGLDTQAAEAIYQ
HLAYLAQSEDVAVMVISHNLRQLLTVADRILVLRDGKLVEITTAANIRNGTCDSYTQSLWAALPEHWGLTNANAA

Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI157502203, Length=211, Percent_Identity=27.0142180094787, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI157502201, Length=211, Percent_Identity=27.0142180094787, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789963, Length=258, Percent_Identity=32.5581395348837, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI145693107, Length=264, Percent_Identity=29.1666666666667, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788506, Length=261, Percent_Identity=30.2681992337165, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI48994883, Length=246, Percent_Identity=26.8292682926829, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787548, Length=239, Percent_Identity=27.6150627615063, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787759, Length=245, Percent_Identity=26.1224489795918, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787758, Length=236, Percent_Identity=28.3898305084746, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789890, Length=237, Percent_Identity=27.8481012658228, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787547, Length=233, Percent_Identity=25.3218884120172, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789962, Length=229, Percent_Identity=27.5109170305677, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787500, Length=227, Percent_Identity=26.431718061674, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789032, Length=218, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=213, Percent_Identity=24.8826291079812, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787105, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1787712, Length=222, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788165, Length=199, Percent_Identity=25.6281407035176, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787792, Length=251, Percent_Identity=27.4900398406374, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790544, Length=250, Percent_Identity=26.8, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786398, Length=233, Percent_Identity=24.8927038626609, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994943, Length=244, Percent_Identity=25.8196721311475, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786563, Length=208, Percent_Identity=24.5192307692308, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789751, Length=224, Percent_Identity=25, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1787370, Length=208, Percent_Identity=23.5576923076923, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788761, Length=200, Percent_Identity=25, Blast_Score=61, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221500365, Length=197, Percent_Identity=28.9340101522843, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007184, Length=197, Percent_Identity=28.9340101522843, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 25248; Mature: 25248

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCVDKLSIQSSDICLLSPLSFSIAKGEVFGVVGASGSGKSLLAQALLGQVPDGFNLSGQ
CCCCCCCCCCCCCEEEECCCCCEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHH
VLHRSGDRRVLAAQSASVLDPLRRISSQLSYALSRVPKGATRKRRFPLAADITRCYRHQL
HEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHH
SGGMAKRALLAQACWQASEIMIADEPCCGLDTQAAEAIYQHLAYLAQSEDVAVMVISHNL
CCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
RQLLTVADRILVLRDGKLVEITTAANIRNGTCDSYTQSLWAALPEHWGLTNANAA
HHHHHHHHHEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLCVDKLSIQSSDICLLSPLSFSIAKGEVFGVVGASGSGKSLLAQALLGQVPDGFNLSGQ
CCCCCCCCCCCCCEEEECCCCCEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHH
VLHRSGDRRVLAAQSASVLDPLRRISSQLSYALSRVPKGATRKRRFPLAADITRCYRHQL
HEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHH
SGGMAKRALLAQACWQASEIMIADEPCCGLDTQAAEAIYQHLAYLAQSEDVAVMVISHNL
CCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
RQLLTVADRILVLRDGKLVEITTAANIRNGTCDSYTQSLWAALPEHWGLTNANAA
HHHHHHHHHEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]