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The map label for this gene is appB [H]

Identifier: 167625632

GI number: 167625632

Start: 4523981

End: 4524958

Strand: Reverse

Name: appB [H]

Synonym: Shal_3727

Alternate gene names: 167625632

Gene position: 4524958-4523981 (Counterclockwise)

Preceding gene: 167625633

Following gene: 167625631

Centisome position: 86.57

GC content: 51.02

Gene sequence:

>978_bases
ATGAGAAATCTACCCGCTTCGCTACTCAATACCTGTCTACGGCTAGTACTGCTGTTAATTTTGGTTATCTTACTCGCTTA
CTTCTTGCTTAGCTGGTCGCCACTCGATCCTATTAATGCCTATCTTGGCGGCAATGTTTTTGCGGTGTCTGAGGCACAAA
AAGCTCTGCTAGAGAGTCAGTTGTCATTGGATCAAGATGTCGGAGAGCGTCTGCTACACTGGCTTGGTGGCTTGCTGCAG
GGGGATTTAGGTTACTCAAGCCTCTATCAACAACCTGTGTCGAGTGTGATTGCCGAACGTTTGCCGATCTCACTGCTACT
CATTGGGCTTAGCTGGGTCTGCTCGCTAGTTCTTGGTTATTTATTGGGATTAATCGCGGCAGTCTATCGCGGCGGCTGGT
TAGATCGCATTATTCAAAAGTTCGCTTGGTTGATGGTCTGTATGCCATCGTTCTGGCTAGCGATGCTGTTAATTAGCCTG
TTCTCTATTGGCCTTAGCCTGACCCCTGTTTGCTGCGCAGCACCGATAGGAATGACGTTTACCGAGCAGTCGTTAGCTAG
CATGTTGCAACACCTGCTATTGCCCGTCGTTACGTTGACGGCGGTGAGCATGGCGCCGATTATGCTGCATACCCGTGAGA
AGGTGATTGATGTACTGCAGTCTGATTATGTGCAGTACTCCTTAGCGCATGGTGATGGCCTGTCCAAAGTGGTGCTGTTT
CATGTGATCCGCAATAGCCTGCTGCCGGCGATTATCCTGCAATTTGCCACCGTCGCTGAGCTGTTTGGCGGCTCCCTGAT
TGCAGAAAGCGTGTTTAGCTTTCCTGGGATCGGGGCGAGTATCGTTAAGGCTGGCTTGGCCAGTGATACCGGCTTGCTGA
TGGGCTGCACCCTGATCTCGGCGCTACTCGTCTTTGGCGGAAACTTGATCGCCAGCTTACTTTCACGCCGCTTTATGGTG
GAGGCGAGTGATGCATAA

Upstream 100 bases:

>100_bases
ACGAATGCTTAGATCTTGCTAAGCCCGGCATAGAGGCTCACGGACATGGTTGGCCGCTGGCCAATAATATTGAGCAGTGG
CGTTGGCTATGTCCTAAGCG

Downstream 100 bases:

>100_bases
AAGCTACTGCGTCAGCTCAGCTCTCTTTCGGAGATGCAAAATGCGCAATATGTCGCGCCAGCCGATATGTATGCAGGAGG
CGAAAGATGCATAGCACACT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRNLPASLLNTCLRLVLLLILVILLAYFLLSWSPLDPINAYLGGNVFAVSEAQKALLESQLSLDQDVGERLLHWLGGLLQ
GDLGYSSLYQQPVSSVIAERLPISLLLIGLSWVCSLVLGYLLGLIAAVYRGGWLDRIIQKFAWLMVCMPSFWLAMLLISL
FSIGLSLTPVCCAAPIGMTFTEQSLASMLQHLLLPVVTLTAVSMAPIMLHTREKVIDVLQSDYVQYSLAHGDGLSKVVLF
HVIRNSLLPAIILQFATVAELFGGSLIAESVFSFPGIGASIVKAGLASDTGLLMGCTLISALLVFGGNLIASLLSRRFMV
EASDA

Sequences:

>Translated_325_residues
MRNLPASLLNTCLRLVLLLILVILLAYFLLSWSPLDPINAYLGGNVFAVSEAQKALLESQLSLDQDVGERLLHWLGGLLQ
GDLGYSSLYQQPVSSVIAERLPISLLLIGLSWVCSLVLGYLLGLIAAVYRGGWLDRIIQKFAWLMVCMPSFWLAMLLISL
FSIGLSLTPVCCAAPIGMTFTEQSLASMLQHLLLPVVTLTAVSMAPIMLHTREKVIDVLQSDYVQYSLAHGDGLSKVVLF
HVIRNSLLPAIILQFATVAELFGGSLIAESVFSFPGIGASIVKAGLASDTGLLMGCTLISALLVFGGNLIASLLSRRFMV
EASDA
>Mature_325_residues
MRNLPASLLNTCLRLVLLLILVILLAYFLLSWSPLDPINAYLGGNVFAVSEAQKALLESQLSLDQDVGERLLHWLGGLLQ
GDLGYSSLYQQPVSSVIAERLPISLLLIGLSWVCSLVLGYLLGLIAAVYRGGWLDRIIQKFAWLMVCMPSFWLAMLLISL
FSIGLSLTPVCCAAPIGMTFTEQSLASMLQHLLLPVVTLTAVSMAPIMLHTREKVIDVLQSDYVQYSLAHGDGLSKVVLF
HVIRNSLLPAIILQFATVAELFGGSLIAESVFSFPGIGASIVKAGLASDTGLLMGCTLISALLVFGGNLIASLLSRRFMV
EASDA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=308, Percent_Identity=31.1688311688312, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789965, Length=312, Percent_Identity=28.2051282051282, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789888, Length=312, Percent_Identity=30.4487179487179, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787550, Length=262, Percent_Identity=29.0076335877863, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787761, Length=311, Percent_Identity=27.6527331189711, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=26.2987012987013, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788504, Length=277, Percent_Identity=26.3537906137184, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35050; Mature: 35050

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLPASLLNTCLRLVLLLILVILLAYFLLSWSPLDPINAYLGGNVFAVSEAQKALLESQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHH
LSLDQDVGERLLHWLGGLLQGDLGYSSLYQQPVSSVIAERLPISLLLIGLSWVCSLVLGY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGLIAAVYRGGWLDRIIQKFAWLMVCMPSFWLAMLLISLFSIGLSLTPVCCAAPIGMTF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TEQSLASMLQHLLLPVVTLTAVSMAPIMLHTREKVIDVLQSDYVQYSLAHGDGLSKVVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HVIRNSLLPAIILQFATVAELFGGSLIAESVFSFPGIGASIVKAGLASDTGLLMGCTLIS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHH
ALLVFGGNLIASLLSRRFMVEASDA
HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRNLPASLLNTCLRLVLLLILVILLAYFLLSWSPLDPINAYLGGNVFAVSEAQKALLESQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHH
LSLDQDVGERLLHWLGGLLQGDLGYSSLYQQPVSSVIAERLPISLLLIGLSWVCSLVLGY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGLIAAVYRGGWLDRIIQKFAWLMVCMPSFWLAMLLISLFSIGLSLTPVCCAAPIGMTF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TEQSLASMLQHLLLPVVTLTAVSMAPIMLHTREKVIDVLQSDYVQYSLAHGDGLSKVVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HVIRNSLLPAIILQFATVAELFGGSLIAESVFSFPGIGASIVKAGLASDTGLLMGCTLIS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHH
ALLVFGGNLIASLLSRRFMVEASDA
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]