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The map label for this gene is dsbD [H]

Identifier: 167625193

GI number: 167625193

Start: 3999804

End: 4001861

Strand: Reverse

Name: dsbD [H]

Synonym: Shal_3281

Alternate gene names: 167625193

Gene position: 4001861-3999804 (Counterclockwise)

Preceding gene: 167625194

Following gene: 167625192

Centisome position: 76.56

GC content: 46.45

Gene sequence:

>2058_bases
TTGAAAATAATAAAACAGATCATTTTAGTGTGCTTGATAGCACTGGCTAATCCGGTCTTCGCCCAATCAACGGGGTGGCT
AGAAAACCCAAATCATCCACCGGTTAAAGCAAGATTTATGCTTACTGGAGAGTTAGACAAAGCCACAAATACGATGCCTG
GTGTACTTGAAGTTGAGCTTGATGGCGAGTGGAAAACCTACTGGCGTAGCCCTGGTGAAGGCGGCATTGCACCGAGTATT
GATTGGAGTGGCTCAACTAATTTAGACAATGTAAATTGGAATTGGCCTGCACCTGAGCAGTTTTCACTGCTTGGACTACA
AACTTTTGGCTATCACCAACAGGCTGCATTTCCTATGTTGGTAACGCTGAACGATGCCTCTAAACCTGCTAGTTTACAGG
GTAAATTCACCTTATCTTCATGTACCAATATCTGCGTGTTAACCGACTACGATATTAATTTAGAGATCGATCCTCGTGAG
CTTAACTCTGATGTCGGTGCGATGTTTTCCTACAACAAAGCACTGTCTAAGGTACCGCAGAAGAAGATCAGCGACACCCT
AGTGTTTGGCTGGGATGCTAAAGCTAAGCAGCTACAGGTGGAGATGGATGACACTGGCTGGATAATGCCTAAGTTTATTG
TCGATGGTGAGCCTGATACCACGTTTAAATTTGTCATATTTGAGCGTTTTGAAACCGATACCGCAGCGAAAAAACTCAGA
GCGGTATTTGATGCATCAAGTTGGTTGGGAGAGCCAGAGCTGCTCGGTAAGCCACTCAATTTAACTGTGATAGACAGTAA
TCGCGCCGTGGAGTACACCTCTAAAGTTGAAGCTACCACGATTAAATCGAGCCAGACTTCGCTTTTAAAAATGCTGTTAA
TAGCGCTTTTAGGCGGCTTAATACTTAATGTTATGCCTTGTGTTTTACCTGTTCTGGGGATGAAGTTAAGTGCCGTTATC
GCCGCGCCCGATCTGCAGCGCAGGCAAATTCGTCAACAGTTTATCGCTTCAGCACTCGGCATTTTGGTGTCATTTTGGTT
ACTCGCGGCCTTTATTTTCACCCTTAAACTGACCGGACAAGCAATAGGTTGGGGCGTTCAGTTCCAGAACCCATGGTTTA
TTGGGTTTATGGCGATTGTGACCTCGGTGTTTGCGTTGAATATGTTAGGCGCATTTGAGATCACTTTGCCATCGAATCTA
CAAACAAAGCTGGCGACAACAGGCGGCAATGATCATCGCGGACACTTTTTGCAAGGCATGTTTGCCACCTTGCTGGCAAC
GCCCTGCAGCGCGCCTTTTCTGGGCACCGCAGTCGCTTTTGCCTTAGGCGCTGACGTCTTGAGTCTGTTTGTCATCTTTA
CCGCTTTAGCATTAGGCATGGCATTGCCTTGGTTAGTGGTAGCCGCATTCCCACAAGTTGCGAATTACTTCCCTAAACCG
GGGCGTTGGATGAATGTGGTTAAAGTGGTGTTCTCGGGCCTACTGGTACTGACCAGTCTGTGGCTAATCAGTTTGTTAGC
TAACTTCATCCCTACGGTTTATTTGTGGATTGCGGCGGCTATTCTTTTACTGTTGTTCTTGATGTTGATGGCCAAAGTAC
AAGGTAAAGCCGCTGTCATCGCCAGTGTCAGTATCGGGATTATGGTATTAGCCGTTGCAGCATTTTCGACATCAAACAGG
TGGGCGCAGCCGTTACCTACAGACTTAGATTGGCGTGCTCTGAATGAATCAGAAATAGCGAGACAAGTTGCGGCAGGCAA
AACCGTGTTTGTCGATGTTACTGCCGATTGGTGTATCACCTGTAAAGCCAACAAGGTGGGGGTGATCTTACAAGATCCGG
TATACAGCGAATTGAAAACTGAAAATATAGTGTTGATGGAGGGGGACTGGACCAAGCCGTCAGCGCCAATAACCGAATAT
TTACAGAGTCATAATCGTTTTGGTGTGCCGTTTAATGTGGTTTACGGTCCGAATGCACCTGAGGGAATTGCCCTGCCGGT
GATCTTGTCTGCCAGCGATGTTATCGATGCTATCAACGTGGCTTCGGTAAGATTTTGA

Upstream 100 bases:

>100_bases
TGCTGTTATTTTGTTTAATATTAAGCCGTTAATTAACACTTTGCCTAGCAGCCTATATGGGGCTAAAAGGTTTTGTGAGC
CGTTTTCGCGGAGAGATAAA

Downstream 100 bases:

>100_bases
TTTAAAGCCGCGCCTCAAGCATTTGGACAATAGCGCACAGTGCAAGCGCTTAACCGTTATAAATAGAGCGCTACTATTAG
CAGCGCCACGAGATAATCTA

Product: cytochrome c biogenesis protein transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MKIIKQIILVCLIALANPVFAQSTGWLENPNHPPVKARFMLTGELDKATNTMPGVLEVELDGEWKTYWRSPGEGGIAPSI
DWSGSTNLDNVNWNWPAPEQFSLLGLQTFGYHQQAAFPMLVTLNDASKPASLQGKFTLSSCTNICVLTDYDINLEIDPRE
LNSDVGAMFSYNKALSKVPQKKISDTLVFGWDAKAKQLQVEMDDTGWIMPKFIVDGEPDTTFKFVIFERFETDTAAKKLR
AVFDASSWLGEPELLGKPLNLTVIDSNRAVEYTSKVEATTIKSSQTSLLKMLLIALLGGLILNVMPCVLPVLGMKLSAVI
AAPDLQRRQIRQQFIASALGILVSFWLLAAFIFTLKLTGQAIGWGVQFQNPWFIGFMAIVTSVFALNMLGAFEITLPSNL
QTKLATTGGNDHRGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFVIFTALALGMALPWLVVAAFPQVANYFPKP
GRWMNVVKVVFSGLLVLTSLWLISLLANFIPTVYLWIAAAILLLLFLMLMAKVQGKAAVIASVSIGIMVLAVAAFSTSNR
WAQPLPTDLDWRALNESEIARQVAAGKTVFVDVTADWCITCKANKVGVILQDPVYSELKTENIVLMEGDWTKPSAPITEY
LQSHNRFGVPFNVVYGPNAPEGIALPVILSASDVIDAINVASVRF

Sequences:

>Translated_685_residues
MKIIKQIILVCLIALANPVFAQSTGWLENPNHPPVKARFMLTGELDKATNTMPGVLEVELDGEWKTYWRSPGEGGIAPSI
DWSGSTNLDNVNWNWPAPEQFSLLGLQTFGYHQQAAFPMLVTLNDASKPASLQGKFTLSSCTNICVLTDYDINLEIDPRE
LNSDVGAMFSYNKALSKVPQKKISDTLVFGWDAKAKQLQVEMDDTGWIMPKFIVDGEPDTTFKFVIFERFETDTAAKKLR
AVFDASSWLGEPELLGKPLNLTVIDSNRAVEYTSKVEATTIKSSQTSLLKMLLIALLGGLILNVMPCVLPVLGMKLSAVI
AAPDLQRRQIRQQFIASALGILVSFWLLAAFIFTLKLTGQAIGWGVQFQNPWFIGFMAIVTSVFALNMLGAFEITLPSNL
QTKLATTGGNDHRGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFVIFTALALGMALPWLVVAAFPQVANYFPKP
GRWMNVVKVVFSGLLVLTSLWLISLLANFIPTVYLWIAAAILLLLFLMLMAKVQGKAAVIASVSIGIMVLAVAAFSTSNR
WAQPLPTDLDWRALNESEIARQVAAGKTVFVDVTADWCITCKANKVGVILQDPVYSELKTENIVLMEGDWTKPSAPITEY
LQSHNRFGVPFNVVYGPNAPEGIALPVILSASDVIDAINVASVRF
>Mature_685_residues
MKIIKQIILVCLIALANPVFAQSTGWLENPNHPPVKARFMLTGELDKATNTMPGVLEVELDGEWKTYWRSPGEGGIAPSI
DWSGSTNLDNVNWNWPAPEQFSLLGLQTFGYHQQAAFPMLVTLNDASKPASLQGKFTLSSCTNICVLTDYDINLEIDPRE
LNSDVGAMFSYNKALSKVPQKKISDTLVFGWDAKAKQLQVEMDDTGWIMPKFIVDGEPDTTFKFVIFERFETDTAAKKLR
AVFDASSWLGEPELLGKPLNLTVIDSNRAVEYTSKVEATTIKSSQTSLLKMLLIALLGGLILNVMPCVLPVLGMKLSAVI
AAPDLQRRQIRQQFIASALGILVSFWLLAAFIFTLKLTGQAIGWGVQFQNPWFIGFMAIVTSVFALNMLGAFEITLPSNL
QTKLATTGGNDHRGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFVIFTALALGMALPWLVVAAFPQVANYFPKP
GRWMNVVKVVFSGLLVLTSLWLISLLANFIPTVYLWIAAAILLLLFLMLMAKVQGKAAVIASVSIGIMVLAVAAFSTSNR
WAQPLPTDLDWRALNESEIARQVAAGKTVFVDVTADWCITCKANKVGVILQDPVYSELKTENIVLMEGDWTKPSAPITEY
LQSHNRFGVPFNVVYGPNAPEGIALPVILSASDVIDAINVASVRF

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=381, Percent_Identity=26.509186351706, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 74833; Mature: 74833

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIKQIILVCLIALANPVFAQSTGWLENPNHPPVKARFMLTGELDKATNTMPGVLEVEL
CHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEE
DGEWKTYWRSPGEGGIAPSIDWSGSTNLDNVNWNWPAPEQFSLLGLQTFGYHQQAAFPML
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCEEE
VTLNDASKPASLQGKFTLSSCTNICVLTDYDINLEIDPRELNSDVGAMFSYNKALSKVPQ
EEECCCCCCCCCCCEEEHHCCCCEEEEEECCEEEEECHHHHCCCHHHHHHHHHHHHHCCH
KKISDTLVFGWDAKAKQLQVEMDDTGWIMPKFIVDGEPDTTFKFVIFERFETDTAAKKLR
HHCCCCEEEECCCCCEEEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECCCHHHHHHHH
AVFDASSWLGEPELLGKPLNLTVIDSNRAVEYTSKVEATTIKSSQTSLLKMLLIALLGGL
HHHHHHHHCCCHHHCCCCCEEEEECCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHH
ILNVMPCVLPVLGMKLSAVIAAPDLQRRQIRQQFIASALGILVSFWLLAAFIFTLKLTGQ
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AIGWGVQFQNPWFIGFMAIVTSVFALNMLGAFEITLPSNLQTKLATTGGNDHRGHFLQGM
EEEECEEECCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHH
FATLLATPCSAPFLGTAVAFALGADVLSLFVIFTALALGMALPWLVVAAFPQVANYFPKP
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GRWMNVVKVVFSGLLVLTSLWLISLLANFIPTVYLWIAAAILLLLFLMLMAKVQGKAAVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ASVSIGIMVLAVAAFSTSNRWAQPLPTDLDWRALNESEIARQVAAGKTVFVDVTADWCIT
EHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEEEE
CKANKVGVILQDPVYSELKTENIVLMEGDWTKPSAPITEYLQSHNRFGVPFNVVYGPNAP
EECCCEEEEECCCCHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCC
EGIALPVILSASDVIDAINVASVRF
CCEEEEEEECHHHHHHHHHHHEECC
>Mature Secondary Structure
MKIIKQIILVCLIALANPVFAQSTGWLENPNHPPVKARFMLTGELDKATNTMPGVLEVEL
CHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEE
DGEWKTYWRSPGEGGIAPSIDWSGSTNLDNVNWNWPAPEQFSLLGLQTFGYHQQAAFPML
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCEEE
VTLNDASKPASLQGKFTLSSCTNICVLTDYDINLEIDPRELNSDVGAMFSYNKALSKVPQ
EEECCCCCCCCCCCEEEHHCCCCEEEEEECCEEEEECHHHHCCCHHHHHHHHHHHHHCCH
KKISDTLVFGWDAKAKQLQVEMDDTGWIMPKFIVDGEPDTTFKFVIFERFETDTAAKKLR
HHCCCCEEEECCCCCEEEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECCCHHHHHHHH
AVFDASSWLGEPELLGKPLNLTVIDSNRAVEYTSKVEATTIKSSQTSLLKMLLIALLGGL
HHHHHHHHCCCHHHCCCCCEEEEECCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHH
ILNVMPCVLPVLGMKLSAVIAAPDLQRRQIRQQFIASALGILVSFWLLAAFIFTLKLTGQ
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AIGWGVQFQNPWFIGFMAIVTSVFALNMLGAFEITLPSNLQTKLATTGGNDHRGHFLQGM
EEEECEEECCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHH
FATLLATPCSAPFLGTAVAFALGADVLSLFVIFTALALGMALPWLVVAAFPQVANYFPKP
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GRWMNVVKVVFSGLLVLTSLWLISLLANFIPTVYLWIAAAILLLLFLMLMAKVQGKAAVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ASVSIGIMVLAVAAFSTSNRWAQPLPTDLDWRALNESEIARQVAAGKTVFVDVTADWCIT
EHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEEEE
CKANKVGVILQDPVYSELKTENIVLMEGDWTKPSAPITEYLQSHNRFGVPFNVVYGPNAP
EECCCEEEEECCCCHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCC
EGIALPVILSASDVIDAINVASVRF
CCEEEEEEECHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA