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The map label for this gene is nqrA [H]

Identifier: 167625099

GI number: 167625099

Start: 3891190

End: 3892530

Strand: Reverse

Name: nqrA [H]

Synonym: Shal_3187

Alternate gene names: 167625099

Gene position: 3892530-3891190 (Counterclockwise)

Preceding gene: 167625100

Following gene: 167625098

Centisome position: 74.47

GC content: 45.86

Gene sequence:

>1341_bases
ATGGATATGATTACAATAAAGAAAGGATTGGACCTGCCTATAGCAGGCGGGCCAGAGCAAGTTATCCATGATGGTAAAGC
CATCAAACACGTAGCTATTTTGGGTGAAGAGTATATTGGCTTACGTCCTACCATGAAAATTAAGGTGGGAGACAAAGTTA
AAAAAGGCCAGGTTATTTTTGAAGATAAAAAGAACCTTGGTGTTAAATATACAGCTTTAGCCAGTGGCATAATTAAAGAA
GTTAACCGGGGCGCTCAGCGTGTTCTGCAGTCTGTTGTTATAGATGTTGAAGGAGATGAAAGTATCTCTTTTACTAAATA
TAACGCCACTGCTATCGACACGCTTGAGGATCAGCAAGTACGTGACAACCTGATCCAATCAGGTTTGTGGACTGCTCTGC
GTACACGTCCTTTCAGTCGAGTACCCGCAGTAGATTCTACCGCTGCCGGCATCTTCGTTACCGCTATAGATACCCAACCT
CTTGCCGCAAACCCCGAAGTGGTTATCGGTGAACATAAAGAAGATTTTGCCAACGGACTTAAGGTTCTGTCGAGATTGAC
CGAAGGTAAAGTGTATCTGTGTAAAGCTCCTGGAGCCGATATTCCGGCTGCTAATGCACAGGTAGAGGAATTTGCAGGAG
TACACCCTGCTGGCCTCGCTGGTACACATATTCATTACCTTCTACCAGCCTCAGTTAACAGAACTGTTTGGCATATTGGT
TATCAAGATGTGATTGCTGTTGGTCAGTTATTCACTACCGGTGAGTTAAATACTCAGCGTGTAATTGCTATTACTGGTCC
CAAAGCGTTGAAACCCAGACTCATTCGTAGTCAGCTCGGTGCTTCTACCGCAGAGATGTCTGCTGGAGAGATTGCCGATG
GTGATGTACGTGTGATCTCAGGTTCGGTACTTAGCGGTCGCACCGCTAACGGACCGCATGCCTACTTAGGGCGTTTCCAT
CAGCAGCTCTCTCTACTTGAAGAGGGGAGAGAGAAGGAGTTTTTCGGTTGGGCCATGCCTGGACCCAATAAGTTCTCTAT
CACTCGCTCTTTTCTAGGTCACCTCTCTCCTTCTCGTCTATTTAACATGACGACAAGTACCGGAGGTTCTGATCGAGCCA
TGGTACCGATTGGTAACTATGAGCGTGTTATGCCGCTAGATATTCTTCCTACCATGCTACTTCGTGACCTTGTTTCTGGC
GACTATGATGGCGCAGCAACTTTAGGTGCACTGGAGTTAGATGAAGAAGATTTAGCACTGTGTACTGTCGTATGCCCAGG
TAAGTATGATTATGCAATTTATCTGCGTGACTGTTTAGATACGATCGTGAGGGAAGGCTAA

Upstream 100 bases:

>100_bases
ATAAATCTGCGCTAGCTCAACACGAATTAGAGGTTTGTTTAAAAACTTGTGTGTTTAGCAGGAACGCGGCGCATTGTCTT
TCCTTCATAACGTAGTGCTT

Downstream 100 bases:

>100_bases
TGGGCTTAAAACAGTTTTTCGAAAATATTGAACCGCAATTTGAAAAAGGCGGTAAATATGAGAAGTTTTATGCGCTCTTT
GAAGCTGCATATACGGTGTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDMITIKKGLDLPIAGGPEQVIHDGKAIKHVAILGEEYIGLRPTMKIKVGDKVKKGQVIFEDKKNLGVKYTALASGIIKE
VNRGAQRVLQSVVIDVEGDESISFTKYNATAIDTLEDQQVRDNLIQSGLWTALRTRPFSRVPAVDSTAAGIFVTAIDTQP
LAANPEVVIGEHKEDFANGLKVLSRLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLAGTHIHYLLPASVNRTVWHIG
YQDVIAVGQLFTTGELNTQRVIAITGPKALKPRLIRSQLGASTAEMSAGEIADGDVRVISGSVLSGRTANGPHAYLGRFH
QQLSLLEEGREKEFFGWAMPGPNKFSITRSFLGHLSPSRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSG
DYDGAATLGALELDEEDLALCTVVCPGKYDYAIYLRDCLDTIVREG

Sequences:

>Translated_446_residues
MDMITIKKGLDLPIAGGPEQVIHDGKAIKHVAILGEEYIGLRPTMKIKVGDKVKKGQVIFEDKKNLGVKYTALASGIIKE
VNRGAQRVLQSVVIDVEGDESISFTKYNATAIDTLEDQQVRDNLIQSGLWTALRTRPFSRVPAVDSTAAGIFVTAIDTQP
LAANPEVVIGEHKEDFANGLKVLSRLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLAGTHIHYLLPASVNRTVWHIG
YQDVIAVGQLFTTGELNTQRVIAITGPKALKPRLIRSQLGASTAEMSAGEIADGDVRVISGSVLSGRTANGPHAYLGRFH
QQLSLLEEGREKEFFGWAMPGPNKFSITRSFLGHLSPSRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSG
DYDGAATLGALELDEEDLALCTVVCPGKYDYAIYLRDCLDTIVREG
>Mature_446_residues
MDMITIKKGLDLPIAGGPEQVIHDGKAIKHVAILGEEYIGLRPTMKIKVGDKVKKGQVIFEDKKNLGVKYTALASGIIKE
VNRGAQRVLQSVVIDVEGDESISFTKYNATAIDTLEDQQVRDNLIQSGLWTALRTRPFSRVPAVDSTAAGIFVTAIDTQP
LAANPEVVIGEHKEDFANGLKVLSRLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLAGTHIHYLLPASVNRTVWHIG
YQDVIAVGQLFTTGELNTQRVIAITGPKALKPRLIRSQLGASTAEMSAGEIADGDVRVISGSVLSGRTANGPHAYLGRFH
QQLSLLEEGREKEFFGWAMPGPNKFSITRSFLGHLSPSRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSG
DYDGAATLGALELDEEDLALCTVVCPGKYDYAIYLRDCLDTIVREG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 48191; Mature: 48191

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMITIKKGLDLPIAGGPEQVIHDGKAIKHVAILGEEYIGLRPTMKIKVGDKVKKGQVIF
CCEEEECCCCCCCCCCCHHHHHHCCHHHEEEEEECHHHCCCCCEEEEEECCCCCCCCEEE
EDKKNLGVKYTALASGIIKEVNRGAQRVLQSVVIDVEGDESISFTKYNATAIDTLEDQQV
ECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCEEECCCCHHHH
RDNLIQSGLWTALRTRPFSRVPAVDSTAAGIFVTAIDTQPLAANPEVVIGEHKEDFANGL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEECCCHHHHHHHH
KVLSRLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLAGTHIHYLLPASVNRTVWHIG
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEC
YQDVIAVGQLFTTGELNTQRVIAITGPKALKPRLIRSQLGASTAEMSAGEIADGDVRVIS
HHHHHHHHHEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEE
GSVLSGRTANGPHAYLGRFHQQLSLLEEGREKEFFGWAMPGPNKFSITRSFLGHLSPSRL
CCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHE
FNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDYDGAATLGALELDEEDLAL
EEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEE
CTVVCPGKYDYAIYLRDCLDTIVREG
EEEECCCCCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MDMITIKKGLDLPIAGGPEQVIHDGKAIKHVAILGEEYIGLRPTMKIKVGDKVKKGQVIF
CCEEEECCCCCCCCCCCHHHHHHCCHHHEEEEEECHHHCCCCCEEEEEECCCCCCCCEEE
EDKKNLGVKYTALASGIIKEVNRGAQRVLQSVVIDVEGDESISFTKYNATAIDTLEDQQV
ECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCEEECCCCHHHH
RDNLIQSGLWTALRTRPFSRVPAVDSTAAGIFVTAIDTQPLAANPEVVIGEHKEDFANGL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEECCCHHHHHHHH
KVLSRLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLAGTHIHYLLPASVNRTVWHIG
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEC
YQDVIAVGQLFTTGELNTQRVIAITGPKALKPRLIRSQLGASTAEMSAGEIADGDVRVIS
HHHHHHHHHEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEE
GSVLSGRTANGPHAYLGRFHQQLSLLEEGREKEFFGWAMPGPNKFSITRSFLGHLSPSRL
CCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHE
FNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDYDGAATLGALELDEEDLAL
EEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEE
CTVVCPGKYDYAIYLRDCLDTIVREG
EEEECCCCCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA