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The map label for this gene is luxS

Identifier: 167625100

GI number: 167625100

Start: 3893211

End: 3893720

Strand: Reverse

Name: luxS

Synonym: Shal_3188

Alternate gene names: 167625100

Gene position: 3893720-3893211 (Counterclockwise)

Preceding gene: 167625101

Following gene: 167625099

Centisome position: 74.49

GC content: 45.1

Gene sequence:

>510_bases
ATGCCGTTATTAGATAGTTTTACCGTTGACCACACACGGATGAATGCGCCTGCAGTGCGCATTGCTAAATCGATGGTGAC
GCCAAAAGGCGATACGATAACGGTATTCGATTTACGTTTTTGTGTACCGAATAAAGAGATCTTAAGTGAACGAGGTATTC
ATACTCTTGAGCACCTGTTTGCCGGATTTATGCGTGAACATTTAAACGGTGATAGTGTCGAGATCATCGATATCTCTCCT
ATGGGGTGTCGCACAGGGTTTTACATGAGCTTAATCGGCGCGCCGACCGAATCTATTGTCGCTGACTCGTGGCTTGCTGC
CATGCAAGACGTGCTTAAGGTTGCGGTCCAGTCAGACATTCCTGAACTTAATGAATATCAATGCGGCACCTTTGAGATGC
ACTCACTTGAGCAGGCGCAAGAGATCGCCCGTAATATTATCGCATCTGGTATCAATGTTAACCGTAACGATGATTTAAGT
TTGAGTGAGGAGATCTTAAAAGGCCTTTAA

Upstream 100 bases:

>100_bases
GTACGTAAGTATCACTTAAGATCAGAATAAGCTTACAGTCGATTAAGGCTGTAGCTAGCATTATGCTCATGAGCTATTAG
GCCGAATTTGGAGAATTAAA

Downstream 100 bases:

>100_bases
CTGACGACATCTTGATTACTTGATTCAAAAAAAGACGGCTGCGGTCGTCTTTTTTGGTATTGGAGTTAATACCAATCACA
TATTTATTGTGATTGGTATA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPLLDSFTVDHTRMNAPAVRIAKSMVTPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMREHLNGDSVEIIDISP
MGCRTGFYMSLIGAPTESIVADSWLAAMQDVLKVAVQSDIPELNEYQCGTFEMHSLEQAQEIARNIIASGINVNRNDDLS
LSEEILKGL

Sequences:

>Translated_169_residues
MPLLDSFTVDHTRMNAPAVRIAKSMVTPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMREHLNGDSVEIIDISP
MGCRTGFYMSLIGAPTESIVADSWLAAMQDVLKVAVQSDIPELNEYQCGTFEMHSLEQAQEIARNIIASGINVNRNDDLS
LSEEILKGL
>Mature_168_residues
PLLDSFTVDHTRMNAPAVRIAKSMVTPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMREHLNGDSVEIIDISPM
GCRTGFYMSLIGAPTESIVADSWLAAMQDVLKVAVQSDIPELNEYQCGTFEMHSLEQAQEIARNIIASGINVNRNDDLSL
SEEILKGL

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=169, Percent_Identity=72.7810650887574, Blast_Score=269, Evalue=7e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_SHEHH (B0TR04)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001675394.1
- ProteinModelPortal:   B0TR04
- SMR:   B0TR04
- GeneID:   5903827
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_3188
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- BioCyc:   SHAL458817:SHAL_3188-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18738; Mature: 18607

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMNAPAVRIAKSMVTPKGDTITVFDLRFCVPNKEILSERGIHTLEHLF
CCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMREHLNGDSVEIIDISPMGCRTGFYMSLIGAPTESIVADSWLAAMQDVLKVAVQSDI
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PELNEYQCGTFEMHSLEQAQEIARNIIASGINVNRNDDLSLSEEILKGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
PLLDSFTVDHTRMNAPAVRIAKSMVTPKGDTITVFDLRFCVPNKEILSERGIHTLEHLF
CCCCCCCCCCHHCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMREHLNGDSVEIIDISPMGCRTGFYMSLIGAPTESIVADSWLAAMQDVLKVAVQSDI
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PELNEYQCGTFEMHSLEQAQEIARNIIASGINVNRNDDLSLSEEILKGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA