Click here to switch to the map view.

The map label for this gene is phoR [H]

Identifier: 167624971

GI number: 167624971

Start: 3729152

End: 3730462

Strand: Reverse

Name: phoR [H]

Synonym: Shal_3058

Alternate gene names: 167624971

Gene position: 3730462-3729152 (Counterclockwise)

Preceding gene: 167624972

Following gene: 167624970

Centisome position: 71.37

GC content: 48.05

Gene sequence:

>1311_bases
ATGTTTGATTCATATTCAGGGTACCGCTTAATTTCACGGCTGGTGATCTATCTAACCTTATGTTTACTGGTTGGATTGCT
ATTTGGTGAAGTGCTTTTGTTCCTATTGTTAGGTTCGCTTTGCCTGTTGCTATGGCACTATCGCCAACTTTCTCGTTTAA
ATTTTTGGTTATGGCATGATCGCCGTCTTACCCCTCCAAACGGTAGTGGCAGTTGGGAAGGGGTGTTCAATGGTATCTAT
CGTTTACAGGGGAAAAATCGTAAACGGGTGTCACAGCTGGCTTTTTTGCTCGGGCGTTTTAGGCAAGGCGCCGAAGCGTT
GCCCGATGCTGCAGTTGTATTAGACTCTGATAATAATATTTTATGGTGTAACAAGCTGGCGCAGCTGCTGCTTGGATTTG
TATGGCCGCAAGACAATGGCCAACGGATCGATAACCTCATCCGCCACCCAGACTTTTCGGCTTACCTGAAAAACAAAGAC
TACCATGAGCCCCTAGAGTTAGCCTCGCCGCAATCGGATAGGCATATTCTTGAGATCCGTATCATGGCTTATGGCTCTGG
GCAGCAATTACTGATTGCTCGAGACATTACTCGTGTACGCCAACTAGAGGGGATGCGAAAAGAGTTTGTTGCTAACGTAT
CACATGAGCTTAAGACCCCATTGACGGTATTGCAGGGCTATTTAGAGATGATGCAGTCGATGGCCGAGCCTGAGTCCCCC
AATGTGCGAGCCATGGATCAGATGCTGCAACAAACTACCCGTATGCGCTCTATGGTTGAGCAGCTGCTGGCTCTATCAAG
AATCGAAGATGCCAGTGATGTGGACCTTGAAGTCAAAGTCAGTATGTCTCAAATGATGGATATTCTACGTGATGAAGCCT
TGGCGCTAGCACAAGAACAATACGAAGTGAGCTTTTACTGTGAGCCAGGACTGGACCTGTATGGCAATGAGTTACTGGTA
CGCAGTGCCTGCTCCAACCTTATCTCAAATGCGATTCGTTACACTGAGCCCGGCGGTAACATAGAGGTCAGTTGGCGAAA
AGTTGCCATAGGTGGCCTATTTAGCGTGAAAGATAACGGTGAAGGCGTTGCCCCGCAGCATATTGGCCGCTTAACTGAGC
GCTTCTATCGGGTCGATAGTGCTCGTTCAAGACAAAGTGGTGGTACAGGTCTGGGGCTGGCTATAGCCAAGCATGCACTG
AGTCACCACCAGAGTGAGCTCAGTATCATGAGTCAGCTAGGTAAGGGCAGTACCTTCAGCTTTGTTATCCCAGCCAATTT
GGTCGAGTTTACCAAGCAAGAGTTGGCTTAA

Upstream 100 bases:

>100_bases
GTTATCGTTTCTCTACCAAGCTTTAGTTTAATAGGCACAAGGTTACTTTTTACGTTATCTTGTGCCAAGTTCTCCCATAT
GGTCGTTATATTGGTTAAAT

Downstream 100 bases:

>100_bases
TCTCCTCCGCACACTTTAACTTTTTGCATAGGGTTGTCATGAAGAACGGGCTTAGGCCTGTTTTTTAGTAATAAATAGCG
ATTAAAACTGTTTGTCATCT

Product: PAS/PAC sensor-containing signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MFDSYSGYRLISRLVIYLTLCLLVGLLFGEVLLFLLLGSLCLLLWHYRQLSRLNFWLWHDRRLTPPNGSGSWEGVFNGIY
RLQGKNRKRVSQLAFLLGRFRQGAEALPDAAVVLDSDNNILWCNKLAQLLLGFVWPQDNGQRIDNLIRHPDFSAYLKNKD
YHEPLELASPQSDRHILEIRIMAYGSGQQLLIARDITRVRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPESP
NVRAMDQMLQQTTRMRSMVEQLLALSRIEDASDVDLEVKVSMSQMMDILRDEALALAQEQYEVSFYCEPGLDLYGNELLV
RSACSNLISNAIRYTEPGGNIEVSWRKVAIGGLFSVKDNGEGVAPQHIGRLTERFYRVDSARSRQSGGTGLGLAIAKHAL
SHHQSELSIMSQLGKGSTFSFVIPANLVEFTKQELA

Sequences:

>Translated_436_residues
MFDSYSGYRLISRLVIYLTLCLLVGLLFGEVLLFLLLGSLCLLLWHYRQLSRLNFWLWHDRRLTPPNGSGSWEGVFNGIY
RLQGKNRKRVSQLAFLLGRFRQGAEALPDAAVVLDSDNNILWCNKLAQLLLGFVWPQDNGQRIDNLIRHPDFSAYLKNKD
YHEPLELASPQSDRHILEIRIMAYGSGQQLLIARDITRVRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPESP
NVRAMDQMLQQTTRMRSMVEQLLALSRIEDASDVDLEVKVSMSQMMDILRDEALALAQEQYEVSFYCEPGLDLYGNELLV
RSACSNLISNAIRYTEPGGNIEVSWRKVAIGGLFSVKDNGEGVAPQHIGRLTERFYRVDSARSRQSGGTGLGLAIAKHAL
SHHQSELSIMSQLGKGSTFSFVIPANLVEFTKQELA
>Mature_436_residues
MFDSYSGYRLISRLVIYLTLCLLVGLLFGEVLLFLLLGSLCLLLWHYRQLSRLNFWLWHDRRLTPPNGSGSWEGVFNGIY
RLQGKNRKRVSQLAFLLGRFRQGAEALPDAAVVLDSDNNILWCNKLAQLLLGFVWPQDNGQRIDNLIRHPDFSAYLKNKD
YHEPLELASPQSDRHILEIRIMAYGSGQQLLIARDITRVRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPESP
NVRAMDQMLQQTTRMRSMVEQLLALSRIEDASDVDLEVKVSMSQMMDILRDEALALAQEQYEVSFYCEPGLDLYGNELLV
RSACSNLISNAIRYTEPGGNIEVSWRKVAIGGLFSVKDNGEGVAPQHIGRLTERFYRVDSARSRQSGGTGLGLAIAKHAL
SHHQSELSIMSQLGKGSTFSFVIPANLVEFTKQELA

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=408, Percent_Identity=51.2254901960784, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=31.3304721030043, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790346, Length=210, Percent_Identity=30.952380952381, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=27.2321428571429, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=30.9417040358744, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=26.5060240963855, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788549, Length=350, Percent_Identity=24, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787894, Length=247, Percent_Identity=28.3400809716599, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=27.972027972028, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=313, Percent_Identity=28.1150159744409, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=28.1938325991189, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=29.5566502463054, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=23.6413043478261, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=287, Percent_Identity=22.6480836236934, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=25.1082251082251, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=23.9043824701195, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788279, Length=218, Percent_Identity=24.7706422018349, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=25.5411255411255, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49341; Mature: 49341

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSYSGYRLISRLVIYLTLCLLVGLLFGEVLLFLLLGSLCLLLWHYRQLSRLNFWLWHD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
RRLTPPNGSGSWEGVFNGIYRLQGKNRKRVSQLAFLLGRFRQGAEALPDAAVVLDSDNNI
CEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
LWCNKLAQLLLGFVWPQDNGQRIDNLIRHPDFSAYLKNKDYHEPLELASPQSDRHILEIR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHCCCCCCCEEEEEE
IMAYGSGQQLLIARDITRVRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPESP
EEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NVRAMDQMLQQTTRMRSMVEQLLALSRIEDASDVDLEVKVSMSQMMDILRDEALALAQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
YEVSFYCEPGLDLYGNELLVRSACSNLISNAIRYTEPGGNIEVSWRKVAIGGLFSVKDNG
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEECEEEEECCCC
EGVAPQHIGRLTERFYRVDSARSRQSGGTGLGLAIAKHALSHHQSELSIMSQLGKGSTFS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
FVIPANLVEFTKQELA
EEECHHHHHHHHHHCC
>Mature Secondary Structure
MFDSYSGYRLISRLVIYLTLCLLVGLLFGEVLLFLLLGSLCLLLWHYRQLSRLNFWLWHD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
RRLTPPNGSGSWEGVFNGIYRLQGKNRKRVSQLAFLLGRFRQGAEALPDAAVVLDSDNNI
CEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
LWCNKLAQLLLGFVWPQDNGQRIDNLIRHPDFSAYLKNKDYHEPLELASPQSDRHILEIR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHCCCCCCCEEEEEE
IMAYGSGQQLLIARDITRVRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPESP
EEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NVRAMDQMLQQTTRMRSMVEQLLALSRIEDASDVDLEVKVSMSQMMDILRDEALALAQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
YEVSFYCEPGLDLYGNELLVRSACSNLISNAIRYTEPGGNIEVSWRKVAIGGLFSVKDNG
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEECEEEEECCCC
EGVAPQHIGRLTERFYRVDSARSRQSGGTGLGLAIAKHALSHHQSELSIMSQLGKGSTFS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
FVIPANLVEFTKQELA
EEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3550103; 9278503; 2187152; 8391104 [H]