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The map label for this gene is gltS [H]

Identifier: 167624951

GI number: 167624951

Start: 3704866

End: 3706095

Strand: Reverse

Name: gltS [H]

Synonym: Shal_3038

Alternate gene names: 167624951

Gene position: 3706095-3704866 (Counterclockwise)

Preceding gene: 167624953

Following gene: 167624950

Centisome position: 70.9

GC content: 44.96

Gene sequence:

>1230_bases
ATGGAACCACAGTTAATTGAAATTAAAGACTTTGTCTCATTTACCTTAGCGATCATTGCGCTATTTATCGGTAAAAGTAT
CATCTCTCGATACGAGCTACTCAGAAAATACAGTATTCCTGAGCCCGTTGTTGGTGGCTTCGCTTGCGCCGCTATCGTGG
GCATCCTCTATTATGCCTTCGATATTCAGATCGAGTTTAACCTCGAAGTTCGCGATGTGCTGTTGCTCTATTTCTTTGCG
GGAATTGGTTTAAAGGCTGATTTTGCAACACTGCTTAAAGGCGGCAAGCCGCTACTTATCTTAATTATGTTGGCGAGTGT
ATTCATCTTCCTGCAAAACTTTACTGGTGTGACCATCGCCTCACTGTTCGGCTTAGATCCTAAGGCTGGCTTGATGTCGG
GGTCGATTGCACTGATTGGTGGCGTTGGCACTGCAATGGCTTGGACCCCAACCTTTGTTGAAGAGCTGGGCATCGTCAAT
GCGAGCGAGCTGGGCATTGCCTCTAATACCCTAGGACTAATTTCTGCCTGTGTGATTGGTGGTCCTATTGCAGCGTATTT
GATGAAACGCCATAAGGTTCAGGCTAACCATGACTCAGAGCTTGATATTGGTACCAGCCATCAAGCTGGTTCATCACATA
TTAAGGTTGACTACTTTGGGGTGTTGCGAGCTTGGTTATGGCTAAACGTTACCTTAATTATTGGCTATTTTATCGATCTC
GCTTTGCAAGAGGCTGGGGTTAAGCTGCCTATGTTCGTCGCCTGCTTATTGGCTGGTATTATCATCGGTAACGTTGGAAG
AGCCATCATCAATCGCAGAGAGGTCAAAGATAGAGCCTACTTAGATGATGCGTCACAAGGCTTGTCTCTTATTCAAGATA
TCTGCCTAGGTATGTTTCTTACTATGGCTTTGATGAGCCTTAAGATTTGGGAGCTAGAGGGCAGCTTGCTCTATATCTCG
GTGGTGATGTCTGTACAGGTATTGTTATCGATAGTCTTTACCATCTTTGTTGTCTTTAGAATGATGGGCAAAGACTATGA
GGCGGCGGTGATCTGTTCAGGCTTTGGTGGCGTAACCTTGGGCTCTACCGCAACCGCGATTGTGAATATGACGGCGGTGA
CTCAGCAGTATGGTGCGGCGCATAGAGCCTTTATTATTGTACCTCTGGTATGTGGTTTCTTTATCGATATTATCAATGCG
ATGATCATCAATTTATTCGTCTATTTTTAA

Upstream 100 bases:

>100_bases
AGCGAAGTTTAGGTTATCTGTTGGTATTCGGCAGCAAGAGGGGGGAACCTCTCTTTTCAGCTATTTCTTATTAACCTTCC
ACAGGGATTAATCGATTGTC

Downstream 100 bases:

>100_bases
GCCTAGTTTTAAGGCTAGTTTTAAGCGTTAGCGTCAGGCTGTGAACCGGGCGAGATCGATAAGCAAGGACTTGATGCAAA
GAATTAACCGTTTGATTTGA

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MEPQLIEIKDFVSFTLAIIALFIGKSIISRYELLRKYSIPEPVVGGFACAAIVGILYYAFDIQIEFNLEVRDVLLLYFFA
GIGLKADFATLLKGGKPLLILIMLASVFIFLQNFTGVTIASLFGLDPKAGLMSGSIALIGGVGTAMAWTPTFVEELGIVN
ASELGIASNTLGLISACVIGGPIAAYLMKRHKVQANHDSELDIGTSHQAGSSHIKVDYFGVLRAWLWLNVTLIIGYFIDL
ALQEAGVKLPMFVACLLAGIIIGNVGRAIINRREVKDRAYLDDASQGLSLIQDICLGMFLTMALMSLKIWELEGSLLYIS
VVMSVQVLLSIVFTIFVVFRMMGKDYEAAVICSGFGGVTLGSTATAIVNMTAVTQQYGAAHRAFIIVPLVCGFFIDIINA
MIINLFVYF

Sequences:

>Translated_409_residues
MEPQLIEIKDFVSFTLAIIALFIGKSIISRYELLRKYSIPEPVVGGFACAAIVGILYYAFDIQIEFNLEVRDVLLLYFFA
GIGLKADFATLLKGGKPLLILIMLASVFIFLQNFTGVTIASLFGLDPKAGLMSGSIALIGGVGTAMAWTPTFVEELGIVN
ASELGIASNTLGLISACVIGGPIAAYLMKRHKVQANHDSELDIGTSHQAGSSHIKVDYFGVLRAWLWLNVTLIIGYFIDL
ALQEAGVKLPMFVACLLAGIIIGNVGRAIINRREVKDRAYLDDASQGLSLIQDICLGMFLTMALMSLKIWELEGSLLYIS
VVMSVQVLLSIVFTIFVVFRMMGKDYEAAVICSGFGGVTLGSTATAIVNMTAVTQQYGAAHRAFIIVPLVCGFFIDIINA
MIINLFVYF
>Mature_409_residues
MEPQLIEIKDFVSFTLAIIALFIGKSIISRYELLRKYSIPEPVVGGFACAAIVGILYYAFDIQIEFNLEVRDVLLLYFFA
GIGLKADFATLLKGGKPLLILIMLASVFIFLQNFTGVTIASLFGLDPKAGLMSGSIALIGGVGTAMAWTPTFVEELGIVN
ASELGIASNTLGLISACVIGGPIAAYLMKRHKVQANHDSELDIGTSHQAGSSHIKVDYFGVLRAWLWLNVTLIIGYFIDL
ALQEAGVKLPMFVACLLAGIIIGNVGRAIINRREVKDRAYLDDASQGLSLIQDICLGMFLTMALMSLKIWELEGSLLYIS
VVMSVQVLLSIVFTIFVVFRMMGKDYEAAVICSGFGGVTLGSTATAIVNMTAVTQQYGAAHRAFIIVPLVCGFFIDIINA
MIINLFVYF

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=384, Percent_Identity=37.2395833333333, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 44333; Mature: 44333

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPQLIEIKDFVSFTLAIIALFIGKSIISRYELLRKYSIPEPVVGGFACAAIVGILYYAF
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHE
DIQIEFNLEVRDVLLLYFFAGIGLKADFATLLKGGKPLLILIMLASVFIFLQNFTGVTIA
EEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
SLFGLDPKAGLMSGSIALIGGVGTAMAWTPTFVEELGIVNASELGIASNTLGLISACVIG
HHHCCCCCCCCCCCCEEEEECCCHHHHCCHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHH
GPIAAYLMKRHKVQANHDSELDIGTSHQAGSSHIKVDYFGVLRAWLWLNVTLIIGYFIDL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
ALQEAGVKLPMFVACLLAGIIIGNVGRAIINRREVKDRAYLDDASQGLSLIQDICLGMFL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TMALMSLKIWELEGSLLYISVVMSVQVLLSIVFTIFVVFRMMGKDYEAAVICSGFGGVTL
HHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GSTATAIVNMTAVTQQYGAAHRAFIIVPLVCGFFIDIINAMIINLFVYF
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEPQLIEIKDFVSFTLAIIALFIGKSIISRYELLRKYSIPEPVVGGFACAAIVGILYYAF
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHE
DIQIEFNLEVRDVLLLYFFAGIGLKADFATLLKGGKPLLILIMLASVFIFLQNFTGVTIA
EEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
SLFGLDPKAGLMSGSIALIGGVGTAMAWTPTFVEELGIVNASELGIASNTLGLISACVIG
HHHCCCCCCCCCCCCEEEEECCCHHHHCCHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHH
GPIAAYLMKRHKVQANHDSELDIGTSHQAGSSHIKVDYFGVLRAWLWLNVTLIIGYFIDL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
ALQEAGVKLPMFVACLLAGIIIGNVGRAIINRREVKDRAYLDDASQGLSLIQDICLGMFL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TMALMSLKIWELEGSLLYISVVMSVQVLLSIVFTIFVVFRMMGKDYEAAVICSGFGGVTL
HHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GSTATAIVNMTAVTQQYGAAHRAFIIVPLVCGFFIDIINAMIINLFVYF
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]