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The map label for this gene is alr2 [H]

Identifier: 167624749

GI number: 167624749

Start: 3444235

End: 3445455

Strand: Reverse

Name: alr2 [H]

Synonym: Shal_2833

Alternate gene names: 167624749

Gene position: 3445455-3444235 (Counterclockwise)

Preceding gene: 167624750

Following gene: 167624748

Centisome position: 65.92

GC content: 42.42

Gene sequence:

>1221_bases
ATGAAAACCAAATACACTATTATTGCAATGTTTGTAGCATCAATCGGCTCTTTTTCTACGGTAGCCGCGCCATTTTTACC
CAGCGATGGGGTTTCACCGGTTGAAGCTGTACAAGCAGCAAATAGTTGGTTGGAAGTTAACCTTACGCAATTTGATTCCA
ATATCAAAGAGCTTAAAAACCACATACAGTCTAATGTCAAAGTGTGTGCCATTATGAAGGCCGATGCCTATGGCAACGGT
ATTGCGGGATTGATGCCGACCGTTCTCGCCAATAACATTCCTTGCATTGGGGTGACGAGTAATGAAGAGATACGTATCGT
GCGGGATGCAGGTTTTAGGGGGAGTTTGATCCGTGTGCGTTCGGCTTCTATCGCAGAAATTAGCGACACTTTACAGTACG
ATGTAGAAGAGTTTGTGGGAGATGCCAATCAAGCAACACTTTTGTCTGCTATGGCCGCAAAGCTAGATAAACCACTCAAG
GTTCATTTAGTTTTAAATAGTGGTGGCATGGGGCGAAATGGCGTAGATGTCAGTACTCAATCGGGTTTGAACGAAGCCGT
ACAAATTGCAACAACAGCAGATCTCGACGTTGTTGGCATTATGACTCACTTTCCTAGTTATGATCGTGATGACGTATTGG
TGAAGTCAAAGTCGTTCTACAATAGTGCATTAAATATCATCGAAGAATCGGGCCTTAAACGTGACTCAGTAACAATCCAT
TCTGGTAACTCCTACGTGGCGCTGAATGTACCTGAAGCCCATTTTGACATGGTTCGTCCTGGTGGCGTGCTATATGGCGA
TCAACCTACCAATCCTGAGTTTCCATCTATTGTCACTTTTAAAACTCGTATAGCGAGTTTGGTCGATCTTCCGAAGGGGG
CGACAGTTGGTTACGATTCGACTATTAAATTAGAGAGAGAATCACTACTTGCTAATTTACCTGTGGGTTACAGTGATTCT
TTCCCTAGAAAAATGGGTAATACAGCCGATGTGTTAGTTAATGGTCAAAGAGCCAAAGTGATGGGGGTCATATCGATGAA
TACCTCTATGATTGATGTCACTGATTTATCTGGCGTTAAGGAAGGCGATGAGGTTGTTTTGTTTGGATATCAAGGTAAAG
AAAGCATCTTAGCGCCAGAATTTGAAAAAAATGCCGATGTTATATTTCCTGAAATATATACTCAGTGGGGTCAAACAAAT
CCTCGAATCTACGTTAAATAA

Upstream 100 bases:

>100_bases
TGTGCATAATTACAGGTTTTGTAATATGTTAGATCTTCACCACAGATATGGTTGAATAGCTAGGCTATAGTACGTTTTTA
AATCTATCAATCAATCACTT

Downstream 100 bases:

>100_bases
TGACCTTCTAACCTTCACACTCAATACTTGTGTTCTTATACGCTAGTAAAAGCCTGACTTAGCATAAGTCAGGCTTAAGG
CTTAAGGCTATAGGTTATCT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKTKYTIIAMFVASIGSFSTVAAPFLPSDGVSPVEAVQAANSWLEVNLTQFDSNIKELKNHIQSNVKVCAIMKADAYGNG
IAGLMPTVLANNIPCIGVTSNEEIRIVRDAGFRGSLIRVRSASIAEISDTLQYDVEEFVGDANQATLLSAMAAKLDKPLK
VHLVLNSGGMGRNGVDVSTQSGLNEAVQIATTADLDVVGIMTHFPSYDRDDVLVKSKSFYNSALNIIEESGLKRDSVTIH
SGNSYVALNVPEAHFDMVRPGGVLYGDQPTNPEFPSIVTFKTRIASLVDLPKGATVGYDSTIKLERESLLANLPVGYSDS
FPRKMGNTADVLVNGQRAKVMGVISMNTSMIDVTDLSGVKEGDEVVLFGYQGKESILAPEFEKNADVIFPEIYTQWGQTN
PRIYVK

Sequences:

>Translated_406_residues
MKTKYTIIAMFVASIGSFSTVAAPFLPSDGVSPVEAVQAANSWLEVNLTQFDSNIKELKNHIQSNVKVCAIMKADAYGNG
IAGLMPTVLANNIPCIGVTSNEEIRIVRDAGFRGSLIRVRSASIAEISDTLQYDVEEFVGDANQATLLSAMAAKLDKPLK
VHLVLNSGGMGRNGVDVSTQSGLNEAVQIATTADLDVVGIMTHFPSYDRDDVLVKSKSFYNSALNIIEESGLKRDSVTIH
SGNSYVALNVPEAHFDMVRPGGVLYGDQPTNPEFPSIVTFKTRIASLVDLPKGATVGYDSTIKLERESLLANLPVGYSDS
FPRKMGNTADVLVNGQRAKVMGVISMNTSMIDVTDLSGVKEGDEVVLFGYQGKESILAPEFEKNADVIFPEIYTQWGQTN
PRIYVK
>Mature_406_residues
MKTKYTIIAMFVASIGSFSTVAAPFLPSDGVSPVEAVQAANSWLEVNLTQFDSNIKELKNHIQSNVKVCAIMKADAYGNG
IAGLMPTVLANNIPCIGVTSNEEIRIVRDAGFRGSLIRVRSASIAEISDTLQYDVEEFVGDANQATLLSAMAAKLDKPLK
VHLVLNSGGMGRNGVDVSTQSGLNEAVQIATTADLDVVGIMTHFPSYDRDDVLVKSKSFYNSALNIIEESGLKRDSVTIH
SGNSYVALNVPEAHFDMVRPGGVLYGDQPTNPEFPSIVTFKTRIASLVDLPKGATVGYDSTIKLERESLLANLPVGYSDS
FPRKMGNTADVLVNGQRAKVMGVISMNTSMIDVTDLSGVKEGDEVVLFGYQGKESILAPEFEKNADVIFPEIYTQWGQTN
PRIYVK

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=321, Percent_Identity=28.3489096573209, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1790487, Length=335, Percent_Identity=26.2686567164179, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43841; Mature: 43841

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKYTIIAMFVASIGSFSTVAAPFLPSDGVSPVEAVQAANSWLEVNLTQFDSNIKELKN
CCCCCEEHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHCCCEEEEEHHHHCCHHHHHHH
HIQSNVKVCAIMKADAYGNGIAGLMPTVLANNIPCIGVTSNEEIRIVRDAGFRGSLIRVR
HHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCEEEEE
SASIAEISDTLQYDVEEFVGDANQATLLSAMAAKLDKPLKVHLVLNSGGMGRNGVDVSTQ
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHH
SGLNEAVQIATTADLDVVGIMTHFPSYDRDDVLVKSKSFYNSALNIIEESGLKRDSVTIH
CCCCHHEEEEEECCCEEEEHHHHCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCEEEEE
SGNSYVALNVPEAHFDMVRPGGVLYGDQPTNPEFPSIVTFKTRIASLVDLPKGATVGYDS
CCCEEEEEECCHHHHHEECCCCEEECCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCC
TIKLERESLLANLPVGYSDSFPRKMGNTADVLVNGQRAKVMGVISMNTSMIDVTDLSGVK
EEEEEHHHHHEECCCCCCCCCHHHCCCCEEEEEECCCEEEEEEEECCCCEEEEECCCCCC
EGDEVVLFGYQGKESILAPEFEKNADVIFPEIYTQWGQTNPRIYVK
CCCCEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MKTKYTIIAMFVASIGSFSTVAAPFLPSDGVSPVEAVQAANSWLEVNLTQFDSNIKELKN
CCCCCEEHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHCCCEEEEEHHHHCCHHHHHHH
HIQSNVKVCAIMKADAYGNGIAGLMPTVLANNIPCIGVTSNEEIRIVRDAGFRGSLIRVR
HHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCEEEEE
SASIAEISDTLQYDVEEFVGDANQATLLSAMAAKLDKPLKVHLVLNSGGMGRNGVDVSTQ
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHH
SGLNEAVQIATTADLDVVGIMTHFPSYDRDDVLVKSKSFYNSALNIIEESGLKRDSVTIH
CCCCHHEEEEEECCCEEEEHHHHCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCEEEEE
SGNSYVALNVPEAHFDMVRPGGVLYGDQPTNPEFPSIVTFKTRIASLVDLPKGATVGYDS
CCCEEEEEECCHHHHHEECCCCEEECCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCC
TIKLERESLLANLPVGYSDSFPRKMGNTADVLVNGQRAKVMGVISMNTSMIDVTDLSGVK
EEEEEHHHHHEECCCCCCCCCHHHCCCCEEEEEECCCEEEEEEEECCCCEEEEECCCCCC
EGDEVVLFGYQGKESILAPEFEKNADVIFPEIYTQWGQTNPRIYVK
CCCCEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]