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The map label for this gene is yegE [C]

Identifier: 167624570

GI number: 167624570

Start: 3214556

End: 3216280

Strand: Reverse

Name: yegE [C]

Synonym: Shal_2651

Alternate gene names: 167624570

Gene position: 3216280-3214556 (Counterclockwise)

Preceding gene: 167624571

Following gene: 167624567

Centisome position: 61.53

GC content: 38.49

Gene sequence:

>1725_bases
ATGAACCATTCGACACAGCAGACAGTTGCTCTGAGACAATACCTTACAGGCATTATTGGTAATGCTCCGTTCGGGATCTT
GACGATTTCCGAAGAGATGGAAATTAGCATTATAAATGCCGATGCAATCAAGCTACTTGGTTTACCTCTGTCTGATCTAG
CCGATATGGTCGATATTCCATACTCTGAAGCCTTCGTTAATATTCCTGAGTTACAAGAGAACTTTGAAACATCAATTATC
GGAAAACAAAGCCGACAATGTGATTTGTCACGTATTAAAGCTAACGCCTATATTCTAAATATAAAATGTCGAAGTATGCT
TCACGGTACACTCGTTATTATCGAAAATGTCACAAAACAGGCTGAACTTGAAGACAAGTTACTGTATCAAGCGACCCATG
ACAATCTAACAAAACTGGCCAATCGCAAGCAATTTGAAGAAAGACTTAAACGATTTATTGCCAAATCCAAGCTTCATACT
TTATCGGGTGCTGTAATATTTATTGATATTGATCGTTTCAAACCGGTCAATGACACAGCTGGCCATGCTGCGGGCGATGA
GCTCTTAAAACGTGTCACGGCGATCATGAAAACGAATATTAGAGAAAGAGATACTCTCGCAAGACTTGGAGGTGATGAGT
TTTCCATTTTGTTGGAAATGTGTTCACTGAATAAAGCTGTGCAAATCGCTGAAAAAATACGTAAGGAAATTGAGAGTTTT
GTTTTTACTTATGGAAAAAAATCTTTCAAGGTGGGTATTTCGGCCGGTATCTCATTGGTCAATGTGCCTTATGATACGGT
GAGTGCGATTATAAATGCCGCTGATAATGCCTGCCAAATAGCAAAAAATAATGGCCGAAATAGGGTGCATGTTATTAATT
TGGAAAATGGTGAATTAGAGGAGCATATTCGTGAGGTGGAATGGCTAGGCAAACTGAATTGGGCTTTAGCATCAAATCAG
TTTGTTATCTATGCGCAAAAGATCTGTGCAATTGGAGGGGGAGAGGAAAGTAGCCATTTTGAGGTGTTGATTAGACTCAA
GGATGAGGATGGGATGATTATTTCTCCAGGGGTCTTTATTCCACCAGCTGAACGTTATGACCTAATGCCTGATATTGATC
GTTGGGTTCTGAAGGCTACGTTCAGTAAAATTACCCCTTCGTGTAATTATTCAATAAATCTCTCTGGTCAAACACTGTCT
GATGATAGTTTAATCAACTATATCGAAAATTTACTCGATACCTATAACGTTAATCCAAAGCAGATCTGTTTTGAGATCAC
TGAAACGGCAGCGATACAAGAGTTGGACAAAACAGTCGCATTAATAAGTTGTTTAAAACAAAAGGGCTTTTGTTTCTCAT
TAGATGATTTTGGTTCTGGCCTTTCATCATTTTCATATCTTAAAAAATTACCTGTCAACTATTTGAAGATTGATGGCGAC
TTTGTCAAAGATATCGCAACAGACTCCGTTTCTTATGCCATGGTAAAATCAATCAATGAGGTTGGTCATACCATGGGGTT
AAAAACCATCGCTGAATTTGTCGAAAGTGAAGCAATTTTGGCTAAGTTAACCGAAATTGGAGTCGATTACGTTCAAGGTT
ATTATATTCATGAACCACAACCCTTTGAAAAACTTTGCAATACTGTTAATTGTAACCGGGCTGATTGTAATACCACAAAT
TGCAACGCAGCGAATTTATCGTCGATGACACATGCTCCATGTTAG

Upstream 100 bases:

>100_bases
TGTTCTAATTCTTCTAAATCAATCGCAATGAGTATATTTGATCAATATGCCGCCAGTCATGATGAGAGTGACACTGTGAT
AGTAATGAAAGGGTAGTAAA

Downstream 100 bases:

>100_bases
GGCTTTACGATAACAATTGGGTGAAGCAAGGATTTCATTAACGAGAATGAACCGTCCTCGGCAGCAGTTTCTGCGTTACT
CCACGTCCTAAAGCCGTTTA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MNHSTQQTVALRQYLTGIIGNAPFGILTISEEMEISIINADAIKLLGLPLSDLADMVDIPYSEAFVNIPELQENFETSII
GKQSRQCDLSRIKANAYILNIKCRSMLHGTLVIIENVTKQAELEDKLLYQATHDNLTKLANRKQFEERLKRFIAKSKLHT
LSGAVIFIDIDRFKPVNDTAGHAAGDELLKRVTAIMKTNIRERDTLARLGGDEFSILLEMCSLNKAVQIAEKIRKEIESF
VFTYGKKSFKVGISAGISLVNVPYDTVSAIINAADNACQIAKNNGRNRVHVINLENGELEEHIREVEWLGKLNWALASNQ
FVIYAQKICAIGGGEESSHFEVLIRLKDEDGMIISPGVFIPPAERYDLMPDIDRWVLKATFSKITPSCNYSINLSGQTLS
DDSLINYIENLLDTYNVNPKQICFEITETAAIQELDKTVALISCLKQKGFCFSLDDFGSGLSSFSYLKKLPVNYLKIDGD
FVKDIATDSVSYAMVKSINEVGHTMGLKTIAEFVESEAILAKLTEIGVDYVQGYYIHEPQPFEKLCNTVNCNRADCNTTN
CNAANLSSMTHAPC

Sequences:

>Translated_574_residues
MNHSTQQTVALRQYLTGIIGNAPFGILTISEEMEISIINADAIKLLGLPLSDLADMVDIPYSEAFVNIPELQENFETSII
GKQSRQCDLSRIKANAYILNIKCRSMLHGTLVIIENVTKQAELEDKLLYQATHDNLTKLANRKQFEERLKRFIAKSKLHT
LSGAVIFIDIDRFKPVNDTAGHAAGDELLKRVTAIMKTNIRERDTLARLGGDEFSILLEMCSLNKAVQIAEKIRKEIESF
VFTYGKKSFKVGISAGISLVNVPYDTVSAIINAADNACQIAKNNGRNRVHVINLENGELEEHIREVEWLGKLNWALASNQ
FVIYAQKICAIGGGEESSHFEVLIRLKDEDGMIISPGVFIPPAERYDLMPDIDRWVLKATFSKITPSCNYSINLSGQTLS
DDSLINYIENLLDTYNVNPKQICFEITETAAIQELDKTVALISCLKQKGFCFSLDDFGSGLSSFSYLKKLPVNYLKIDGD
FVKDIATDSVSYAMVKSINEVGHTMGLKTIAEFVESEAILAKLTEIGVDYVQGYYIHEPQPFEKLCNTVNCNRADCNTTN
CNAANLSSMTHAPC
>Mature_574_residues
MNHSTQQTVALRQYLTGIIGNAPFGILTISEEMEISIINADAIKLLGLPLSDLADMVDIPYSEAFVNIPELQENFETSII
GKQSRQCDLSRIKANAYILNIKCRSMLHGTLVIIENVTKQAELEDKLLYQATHDNLTKLANRKQFEERLKRFIAKSKLHT
LSGAVIFIDIDRFKPVNDTAGHAAGDELLKRVTAIMKTNIRERDTLARLGGDEFSILLEMCSLNKAVQIAEKIRKEIESF
VFTYGKKSFKVGISAGISLVNVPYDTVSAIINAADNACQIAKNNGRNRVHVINLENGELEEHIREVEWLGKLNWALASNQ
FVIYAQKICAIGGGEESSHFEVLIRLKDEDGMIISPGVFIPPAERYDLMPDIDRWVLKATFSKITPSCNYSINLSGQTLS
DDSLINYIENLLDTYNVNPKQICFEITETAAIQELDKTVALISCLKQKGFCFSLDDFGSGLSSFSYLKKLPVNYLKIDGD
FVKDIATDSVSYAMVKSINEVGHTMGLKTIAEFVESEAILAKLTEIGVDYVQGYYIHEPQPFEKLCNTVNCNRADCNTTN
CNAANLSSMTHAPC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=454, Percent_Identity=29.5154185022026, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787541, Length=439, Percent_Identity=30.0683371298405, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1788849, Length=252, Percent_Identity=32.5396825396825, Blast_Score=149, Evalue=7e-37,
Organism=Escherichia coli, GI87081921, Length=424, Percent_Identity=27.5943396226415, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=37.1308016877637, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87082096, Length=261, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI226510982, Length=423, Percent_Identity=26.7139479905437, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081743, Length=236, Percent_Identity=30.9322033898305, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693134, Length=199, Percent_Identity=35.678391959799, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=32.7777777777778, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081881, Length=183, Percent_Identity=34.9726775956284, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081845, Length=247, Percent_Identity=27.1255060728745, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786507, Length=239, Percent_Identity=29.7071129707113, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081980, Length=239, Percent_Identity=28.8702928870293, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788502, Length=236, Percent_Identity=27.9661016949153, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=28.8135593220339, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=36.3095238095238, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787802, Length=190, Percent_Identity=30, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788085, Length=191, Percent_Identity=30.3664921465969, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=180, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081974, Length=182, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787056, Length=161, Percent_Identity=33.5403726708075, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787055, Length=212, Percent_Identity=26.8867924528302, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788956, Length=93, Percent_Identity=40.8602150537634, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081977, Length=176, Percent_Identity=28.9772727272727, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 63900; Mature: 63900

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHSTQQTVALRQYLTGIIGNAPFGILTISEEMEISIINADAIKLLGLPLSDLADMVDIP
CCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHEECCCHHHHHHHHCCC
YSEAFVNIPELQENFETSIIGKQSRQCDLSRIKANAYILNIKCRSMLHGTLVIIENVTKQ
CHHHHEECHHHHHHHHHHHCCCCCCCCHHHHEECCEEEEEEEEHHHHCCCEEEEEHHHHH
AELEDKLLYQATHDNLTKLANRKQFEERLKRFIAKSKLHTLSGAVIFIDIDRFKPVNDTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
GHAAGDELLKRVTAIMKTNIRERDTLARLGGDEFSILLEMCSLNKAVQIAEKIRKEIESF
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
VFTYGKKSFKVGISAGISLVNVPYDTVSAIINAADNACQIAKNNGRNRVHVINLENGELE
HHHHCCCCEEEEHHHCCEEEECCHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHH
EHIREVEWLGKLNWALASNQFVIYAQKICAIGGGEESSHFEVLIRLKDEDGMIISPGVFI
HHHHHHHHHHHHHHEEECCCEEEEEEHHHHCCCCCCCCEEEEEEEEECCCCEEECCCEEC
PPAERYDLMPDIDRWVLKATFSKITPSCNYSINLSGQTLSDDSLINYIENLLDTYNVNPK
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHH
QICFEITETAAIQELDKTVALISCLKQKGFCFSLDDFGSGLSSFSYLKKLPVNYLKIDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCHHHHHHHHHHCCCCEEEECCH
FVKDIATDSVSYAMVKSINEVGHTMGLKTIAEFVESEAILAKLTEIGVDYVQGYYIHEPQ
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEECCCC
PFEKLCNTVNCNRADCNTTNCNAANLSSMTHAPC
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNHSTQQTVALRQYLTGIIGNAPFGILTISEEMEISIINADAIKLLGLPLSDLADMVDIP
CCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHEECCCHHHHHHHHCCC
YSEAFVNIPELQENFETSIIGKQSRQCDLSRIKANAYILNIKCRSMLHGTLVIIENVTKQ
CHHHHEECHHHHHHHHHHHCCCCCCCCHHHHEECCEEEEEEEEHHHHCCCEEEEEHHHHH
AELEDKLLYQATHDNLTKLANRKQFEERLKRFIAKSKLHTLSGAVIFIDIDRFKPVNDTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
GHAAGDELLKRVTAIMKTNIRERDTLARLGGDEFSILLEMCSLNKAVQIAEKIRKEIESF
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
VFTYGKKSFKVGISAGISLVNVPYDTVSAIINAADNACQIAKNNGRNRVHVINLENGELE
HHHHCCCCEEEEHHHCCEEEECCHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHH
EHIREVEWLGKLNWALASNQFVIYAQKICAIGGGEESSHFEVLIRLKDEDGMIISPGVFI
HHHHHHHHHHHHHHEEECCCEEEEEEHHHHCCCCCCCCEEEEEEEEECCCCEEECCCEEC
PPAERYDLMPDIDRWVLKATFSKITPSCNYSINLSGQTLSDDSLINYIENLLDTYNVNPK
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHH
QICFEITETAAIQELDKTVALISCLKQKGFCFSLDDFGSGLSSFSYLKKLPVNYLKIDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCHHHHHHHHHHCCCCEEEECCH
FVKDIATDSVSYAMVKSINEVGHTMGLKTIAEFVESEAILAKLTEIGVDYVQGYYIHEPQ
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEECCCC
PFEKLCNTVNCNRADCNTTNCNAANLSSMTHAPC
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]