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The map label for this gene is glcB [H]

Identifier: 167624175

GI number: 167624175

Start: 2728391

End: 2730565

Strand: Reverse

Name: glcB [H]

Synonym: Shal_2251

Alternate gene names: 167624175

Gene position: 2730565-2728391 (Counterclockwise)

Preceding gene: 167624176

Following gene: 167624173

Centisome position: 52.24

GC content: 44.92

Gene sequence:

>2175_bases
ATGACTACAAGGATTCGAGTAGGTGGTTTACAAATAGAAAAATCACTTTGGGAGTTGGTAGACAGTGAGATTTGTCCAGG
TACAGGCATAAGCTCGCAGATCTTCTGGACAAAGTTTGAAGGGATAGTCGATGAACTCGGTCCAGTCAATCGACAGCTTT
TGCAAAAACGTGAGCAACTGCAACAACAGATAGATGAGTGGCATAAAGGAAATGCGCAGCACGCTTTTGACTTGAGTGAA
TATAAACAATTCCTAACGGATATAGGTTATCTTGTTGAAGAGGGTAAACCTTTTACTATCAGCACTGAAAATATTGATAG
CGAGATCAGCATTCAAGCAGGTCCACAGCTCGTCGTGCCCGTTAAAAATGCGCGCTTTGCGTTAAATGCAGCCAACGCCC
GTTGGGGCAGCCTATACGATGCTCTTTATGGTACGGATGCTATCCCACAGAGCGAAGGGGCTGAGCTAACAAAGGGTTAT
AATCCTGTGCGCGGTGCAAAGGTCATAGCCTTTGCTAAGTCACACCTTGATAACGCAGCTCCTTTAGCATTAGGTTCTCA
CAGTCTTGTTACTCAGTATTTTATTGAAAATGGTTGCCTTCAGGCCAAACTCAAAAATGGCTCGCAAACGCAGCTTATTC
ACCCAGAACGCTTTGCCGGTTTTCAAGGGAGTGAACAAAACCCAACGGCTGTTCTCATTGTTAATAACGGGCTGCATATT
GAGATCCAAATTGACTCTAGTCACCAGGTGGGTAAGACAGATTTAGCTGGAGTAAAAGATCTATTAGTAGAGGCGGCCGT
CACGACTATTATGGATTGTGAAGACTCAGTTGCAGCGGTAGATGCCGAAGATAAGGTAGAAATATACCGTAACTGGCTTG
GATTAATGCAAGGAAATTTGACTACAACGCTTAATAAAAATGGTAAAGCTATCGTACGTGAGCTAAATGATGACAGAGTT
TATACCTCCGCCAATGGCCAGAGCATTAAACTCCCTGGTCGTAGCCTGCTGTTTGTGCGCAATGTCGGTCATTTGATGAC
GATTGATGCTGTGCTGGATAAAAACGGTGATGAGGTGCCTGAAGGATTTTTAGATGGCATGGTGACAGTACTTGCAGCAA
AGCATGATCTTCAAGGTAATAACAGCCAGCGAAGTAATAGCCGTAAAGGTTCGGTGAATATCGTAAAACCGAAATTGCAT
GGTCCAGAAGAAGTCCAGTTTACATGTGATCTGTTCACGCGAATTGAGGATGCCCTTAAGCTATCTCGAAATACGATTAA
AGTCGGGATCATGGATGAAGAGCGACGCACAACTGTCAACCTTAAAGAGTGTATTCGCGCAGCGTCAGAGAGAGTCGTCT
TTATCAATACTGGCTTTTTAGATAGAACCGGTGATGAAATTCATACTTCGATGCTTGCTGGGCCATTTGTGGCTAAATCA
GTCATGAAGCAGCAAGCTTGGATTAAAGCCTATGAAGATTGGAATGTCGATATCGGACTCGAATGTGGCTTACAAGGTCG
CTCGCAGATAGGTAAAGGCATGTGGCCTATGCCTGATGAAATGGCGGCGATGCTTGAGCAGAAAATTAGCCACCCCAAAG
CTGGGGCTAACACCGCTTGGGTTCCATCCCCTAATGGAGCGGTATTGCACTCCACTCACTACCATCAGGTAAATGTTAGC
GACGTGCAAAATCAGCTTAAGTTGCGAAAGCGTGCAAGTTTAGATGATCTGCTTACAATTCCTTTGATGGCGCAGGGCAC
TGAACTGACCCAAGAGCAAAAGCAATTTGAGTTAGATAACAATGCTCAAGGCATTCTAGGCTATGTTGTACGCTGGGTTG
ATCAAGGCGTAGGCTGCTCTAAAGTACCGGATATCAATAACGTTGGCTTGATGGAGGATAGGGCCACCTTGCGTATTTCA
TCTCAATATTTGGCTAATTGGTTAGCGCATGGGGTGTGTAGCGAGCAGGACGTTATGGCATCGCTTAAGAAGATGGCACG
AGTTGTTGATAAGCAAAATGCTACCGATCCTGAGTATATCAATATGGCACCAAATTTTGACGGTATCGCCTTTAAAGCGG
CTTGTGATCTTATTTTCAAGGGAGAGTTGCAGCCATCGGGTTATACGGAGCCCTTACTGCATGCATATCGAAAACGAGCC
AAGCTTCAGTCTTAG

Upstream 100 bases:

>100_bases
CAAAAATGAGCAGCGCTTGGTATAGGCTAGTTTATATCAATAAGTCCCATTGTTGAAAATGGATAACTCAAAGCTAAAAC
GGATAGATAAAGGGCATATT

Downstream 100 bases:

>100_bases
TCGCTTTATGTGTTACGGGTGATAGTAATAGGCACAGCAAAAAGCCCTAACCGAAGGCTAGGGCTTTTTAATGACTAAAA
TGGTTTACTGATCGCGATAG

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MTTRIRVGGLQIEKSLWELVDSEICPGTGISSQIFWTKFEGIVDELGPVNRQLLQKREQLQQQIDEWHKGNAQHAFDLSE
YKQFLTDIGYLVEEGKPFTISTENIDSEISIQAGPQLVVPVKNARFALNAANARWGSLYDALYGTDAIPQSEGAELTKGY
NPVRGAKVIAFAKSHLDNAAPLALGSHSLVTQYFIENGCLQAKLKNGSQTQLIHPERFAGFQGSEQNPTAVLIVNNGLHI
EIQIDSSHQVGKTDLAGVKDLLVEAAVTTIMDCEDSVAAVDAEDKVEIYRNWLGLMQGNLTTTLNKNGKAIVRELNDDRV
YTSANGQSIKLPGRSLLFVRNVGHLMTIDAVLDKNGDEVPEGFLDGMVTVLAAKHDLQGNNSQRSNSRKGSVNIVKPKLH
GPEEVQFTCDLFTRIEDALKLSRNTIKVGIMDEERRTTVNLKECIRAASERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
VMKQQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKISHPKAGANTAWVPSPNGAVLHSTHYHQVNVS
DVQNQLKLRKRASLDDLLTIPLMAQGTELTQEQKQFELDNNAQGILGYVVRWVDQGVGCSKVPDINNVGLMEDRATLRIS
SQYLANWLAHGVCSEQDVMASLKKMARVVDKQNATDPEYINMAPNFDGIAFKAACDLIFKGELQPSGYTEPLLHAYRKRA
KLQS

Sequences:

>Translated_724_residues
MTTRIRVGGLQIEKSLWELVDSEICPGTGISSQIFWTKFEGIVDELGPVNRQLLQKREQLQQQIDEWHKGNAQHAFDLSE
YKQFLTDIGYLVEEGKPFTISTENIDSEISIQAGPQLVVPVKNARFALNAANARWGSLYDALYGTDAIPQSEGAELTKGY
NPVRGAKVIAFAKSHLDNAAPLALGSHSLVTQYFIENGCLQAKLKNGSQTQLIHPERFAGFQGSEQNPTAVLIVNNGLHI
EIQIDSSHQVGKTDLAGVKDLLVEAAVTTIMDCEDSVAAVDAEDKVEIYRNWLGLMQGNLTTTLNKNGKAIVRELNDDRV
YTSANGQSIKLPGRSLLFVRNVGHLMTIDAVLDKNGDEVPEGFLDGMVTVLAAKHDLQGNNSQRSNSRKGSVNIVKPKLH
GPEEVQFTCDLFTRIEDALKLSRNTIKVGIMDEERRTTVNLKECIRAASERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
VMKQQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKISHPKAGANTAWVPSPNGAVLHSTHYHQVNVS
DVQNQLKLRKRASLDDLLTIPLMAQGTELTQEQKQFELDNNAQGILGYVVRWVDQGVGCSKVPDINNVGLMEDRATLRIS
SQYLANWLAHGVCSEQDVMASLKKMARVVDKQNATDPEYINMAPNFDGIAFKAACDLIFKGELQPSGYTEPLLHAYRKRA
KLQS
>Mature_723_residues
TTRIRVGGLQIEKSLWELVDSEICPGTGISSQIFWTKFEGIVDELGPVNRQLLQKREQLQQQIDEWHKGNAQHAFDLSEY
KQFLTDIGYLVEEGKPFTISTENIDSEISIQAGPQLVVPVKNARFALNAANARWGSLYDALYGTDAIPQSEGAELTKGYN
PVRGAKVIAFAKSHLDNAAPLALGSHSLVTQYFIENGCLQAKLKNGSQTQLIHPERFAGFQGSEQNPTAVLIVNNGLHIE
IQIDSSHQVGKTDLAGVKDLLVEAAVTTIMDCEDSVAAVDAEDKVEIYRNWLGLMQGNLTTTLNKNGKAIVRELNDDRVY
TSANGQSIKLPGRSLLFVRNVGHLMTIDAVLDKNGDEVPEGFLDGMVTVLAAKHDLQGNNSQRSNSRKGSVNIVKPKLHG
PEEVQFTCDLFTRIEDALKLSRNTIKVGIMDEERRTTVNLKECIRAASERVVFINTGFLDRTGDEIHTSMLAGPFVAKSV
MKQQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKISHPKAGANTAWVPSPNGAVLHSTHYHQVNVSD
VQNQLKLRKRASLDDLLTIPLMAQGTELTQEQKQFELDNNAQGILGYVVRWVDQGVGCSKVPDINNVGLMEDRATLRISS
QYLANWLAHGVCSEQDVMASLKKMARVVDKQNATDPEYINMAPNFDGIAFKAACDLIFKGELQPSGYTEPLLHAYRKRAK
LQS

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=727, Percent_Identity=57.3590096286107, Blast_Score=837, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=264, Percent_Identity=28.4090909090909, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 80005; Mature: 79874

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRIRVGGLQIEKSLWELVDSEICPGTGISSQIFWTKFEGIVDELGPVNRQLLQKREQL
CCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
QQQIDEWHKGNAQHAFDLSEYKQFLTDIGYLVEEGKPFTISTENIDSEISIQAGPQLVVP
HHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCEEEEE
VKNARFALNAANARWGSLYDALYGTDAIPQSEGAELTKGYNPVRGAKVIAFAKSHLDNAA
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEHHHHCCCCC
PLALGSHSLVTQYFIENGCLQAKLKNGSQTQLIHPERFAGFQGSEQNPTAVLIVNNGLHI
CEEECCHHHHHHHHHHCCCEEEEECCCCCCEEECHHHHCCCCCCCCCCEEEEEEECCEEE
EIQIDSSHQVGKTDLAGVKDLLVEAAVTTIMDCEDSVAAVDAEDKVEIYRNWLGLMQGNL
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHCCCE
TTTLNKNGKAIVRELNDDRVYTSANGQSIKLPGRSLLFVRNVGHLMTIDAVLDKNGDEVP
EEEECCCCCEEEEECCCCEEEECCCCCEEECCCCEEEEEECCCCEEEEHHHHCCCCCCCC
EGFLDGMVTVLAAKHDLQGNNSQRSNSRKGSVNIVKPKLHGPEEVQFTCDLFTRIEDALK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHH
LSRNTIKVGIMDEERRTTVNLKECIRAASERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
HCCCEEEEEEECCCCCCEECHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VMKQQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKISHPKAGANTAW
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
VPSPNGAVLHSTHYHQVNVSDVQNQLKLRKRASLDDLLTIPLMAQGTELTQEQKQFELDN
CCCCCCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHEECCCEECCCHHHHHHHHHCCCC
NAQGILGYVVRWVDQGVGCSKVPDINNVGLMEDRATLRISSQYLANWLAHGVCSEQDVMA
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCHHHHH
SLKKMARVVDKQNATDPEYINMAPNFDGIAFKAACDLIFKGELQPSGYTEPLLHAYRKRA
HHHHHHHHHHCCCCCCCCEEEECCCCCCEEHHHHCCEEEECCCCCCCCCHHHHHHHHHHH
KLQS
CCCC
>Mature Secondary Structure 
TTRIRVGGLQIEKSLWELVDSEICPGTGISSQIFWTKFEGIVDELGPVNRQLLQKREQL
CCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
QQQIDEWHKGNAQHAFDLSEYKQFLTDIGYLVEEGKPFTISTENIDSEISIQAGPQLVVP
HHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCEEEEE
VKNARFALNAANARWGSLYDALYGTDAIPQSEGAELTKGYNPVRGAKVIAFAKSHLDNAA
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEHHHHCCCCC
PLALGSHSLVTQYFIENGCLQAKLKNGSQTQLIHPERFAGFQGSEQNPTAVLIVNNGLHI
CEEECCHHHHHHHHHHCCCEEEEECCCCCCEEECHHHHCCCCCCCCCCEEEEEEECCEEE
EIQIDSSHQVGKTDLAGVKDLLVEAAVTTIMDCEDSVAAVDAEDKVEIYRNWLGLMQGNL
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHCCCE
TTTLNKNGKAIVRELNDDRVYTSANGQSIKLPGRSLLFVRNVGHLMTIDAVLDKNGDEVP
EEEECCCCCEEEEECCCCEEEECCCCCEEECCCCEEEEEECCCCEEEEHHHHCCCCCCCC
EGFLDGMVTVLAAKHDLQGNNSQRSNSRKGSVNIVKPKLHGPEEVQFTCDLFTRIEDALK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHH
LSRNTIKVGIMDEERRTTVNLKECIRAASERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
HCCCEEEEEEECCCCCCEECHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VMKQQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKISHPKAGANTAW
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
VPSPNGAVLHSTHYHQVNVSDVQNQLKLRKRASLDDLLTIPLMAQGTELTQEQKQFELDN
CCCCCCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHEECCCEECCCHHHHHHHHHCCCC
NAQGILGYVVRWVDQGVGCSKVPDINNVGLMEDRATLRISSQYLANWLAHGVCSEQDVMA
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCHHHHH
SLKKMARVVDKQNATDPEYINMAPNFDGIAFKAACDLIFKGELQPSGYTEPLLHAYRKRA
HHHHHHHHHHCCCCCCCCEEEECCCCCCEEHHHHCCEEEECCCCCCCCCHHHHHHHHHHH
KLQS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA