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The map label for this gene is nahR [H]

Identifier: 167624176

GI number: 167624176

Start: 2730808

End: 2731752

Strand: Reverse

Name: nahR [H]

Synonym: Shal_2252

Alternate gene names: 167624176

Gene position: 2731752-2730808 (Counterclockwise)

Preceding gene: 167624179

Following gene: 167624175

Centisome position: 52.26

GC content: 45.29

Gene sequence:

>945_bases
ATGAATATATCTCGTATCGACTTGAATTTATTGGTTTATCTTGATGTGCTGTTACGTGAGCAGAATGTTACAAAGGCTGC
GGTTCAGCTTGGGATCAGCCAACCTGCAATGAGTAATGGCTTGAAACGTTTGAGGACACTATTTGACGATCCGCTGTTGA
TAAGAACGAGTCAGGGGATGACGCCGACCGAACGAGCACGGGAGTTACAGCCTACAATTAGCGAGTTAATTATTGGCTTA
GAAAAAGCGGTTCAACCACGAGCCAAGTTTAATGCCGGTGAGAGTGAGCAAGTATTTCGAGTGATGGCCAGTGATTACGC
CGAAGCCACCCTTATCCCGCCACTCATCGCTAGGCTTAGAACCGAAGCGCCAAATGTTATCTTAGATATTATGACTCCAA
GTGACGTGAGTTTCACCGATGTTGAACAGGGGCGAGTCGATATGGTTATTAATCGGTTTGACAGTATTCCTCAGTCATTT
CATCAAAAAGTACTTTGGAGTGATGACTTTAGTTGTTTGATTAGCAAGACTAACTCCGTTCTTGAAAAGTTTTCACTAGA
TAGTTACTTAAGGGCTAACCATGTCTGGGTCAGTAAAACGGGTATGGGAGTTGGGGTCGGAATGGATCCGGGCGATGTAC
AGAGACTTGGTTGGGTTGATGAAGCTTTAACACGAATAGGTGTGCAAAGACGGATCACTGTATTTACTCGGCACTACCAA
GCAGCCTGTTTGTTGGCGGAGCAACAAGATTTGATCGCAACAATACCAAGCAAGATGGCAAGGCAGCATGAAAACAATGA
ACGTGTTTGCATCGTGCCGCCGCCGTTTATTATCCAACCTATTGCGCTTACGATGGCCTGGAGTCCACTTCTACAGCACA
ATCCAGCCCATAAGTGGATGCGTCAGCTTATCACTCAAACAGCTGATAGTTTCGGACGTAATTAA

Upstream 100 bases:

>100_bases
CTTTAACAATATGATTAGCGGCGATTGATTACGTTGAAAATATTAGTAGGATTTGTTTAAATAAGTCTAATTGATAGTTT
CTATATCCGGTATTTACCTT

Downstream 100 bases:

>100_bases
AGTGGTTATACCAATCACTTTAAATATTTGATCGCTCTTAGTGAGCTGTATTAGTGTCTTTATTTCAATTTTGATGATTT
TTACACCAAAATGGTCGAGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNISRIDLNLLVYLDVLLREQNVTKAAVQLGISQPAMSNGLKRLRTLFDDPLLIRTSQGMTPTERARELQPTISELIIGL
EKAVQPRAKFNAGESEQVFRVMASDYAEATLIPPLIARLRTEAPNVILDIMTPSDVSFTDVEQGRVDMVINRFDSIPQSF
HQKVLWSDDFSCLISKTNSVLEKFSLDSYLRANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
AACLLAEQQDLIATIPSKMARQHENNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWMRQLITQTADSFGRN

Sequences:

>Translated_314_residues
MNISRIDLNLLVYLDVLLREQNVTKAAVQLGISQPAMSNGLKRLRTLFDDPLLIRTSQGMTPTERARELQPTISELIIGL
EKAVQPRAKFNAGESEQVFRVMASDYAEATLIPPLIARLRTEAPNVILDIMTPSDVSFTDVEQGRVDMVINRFDSIPQSF
HQKVLWSDDFSCLISKTNSVLEKFSLDSYLRANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
AACLLAEQQDLIATIPSKMARQHENNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWMRQLITQTADSFGRN
>Mature_314_residues
MNISRIDLNLLVYLDVLLREQNVTKAAVQLGISQPAMSNGLKRLRTLFDDPLLIRTSQGMTPTERARELQPTISELIIGL
EKAVQPRAKFNAGESEQVFRVMASDYAEATLIPPLIARLRTEAPNVILDIMTPSDVSFTDVEQGRVDMVINRFDSIPQSF
HQKVLWSDDFSCLISKTNSVLEKFSLDSYLRANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
AACLLAEQQDLIATIPSKMARQHENNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWMRQLITQTADSFGRN

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=305, Percent_Identity=23.9344262295082, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081766, Length=258, Percent_Identity=22.8682170542636, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790147, Length=317, Percent_Identity=23.9747634069401, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786820, Length=160, Percent_Identity=28.125, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35372; Mature: 35372

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISRIDLNLLVYLDVLLREQNVTKAAVQLGISQPAMSNGLKRLRTLFDDPLLIRTSQGM
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCC
TPTERARELQPTISELIIGLEKAVQPRAKFNAGESEQVFRVMASDYAEATLIPPLIARLR
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEAPNVILDIMTPSDVSFTDVEQGRVDMVINRFDSIPQSFHQKVLWSDDFSCLISKTNSV
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LEKFSLDSYLRANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
HHHHHHHHHHHHCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AACLLAEQQDLIATIPSKMARQHENNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWM
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHH
RQLITQTADSFGRN
HHHHHHHHHHHCCC
>Mature Secondary Structure
MNISRIDLNLLVYLDVLLREQNVTKAAVQLGISQPAMSNGLKRLRTLFDDPLLIRTSQGM
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCC
TPTERARELQPTISELIIGLEKAVQPRAKFNAGESEQVFRVMASDYAEATLIPPLIARLR
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEAPNVILDIMTPSDVSFTDVEQGRVDMVINRFDSIPQSFHQKVLWSDDFSCLISKTNSV
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LEKFSLDSYLRANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
HHHHHHHHHHHHCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AACLLAEQQDLIATIPSKMARQHENNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWM
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHH
RQLITQTADSFGRN
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]