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The map label for this gene is ruvA

Identifier: 167623851

GI number: 167623851

Start: 2308127

End: 2308744

Strand: Direct

Name: ruvA

Synonym: Shal_1921

Alternate gene names: 167623851

Gene position: 2308127-2308744 (Clockwise)

Preceding gene: 167623850

Following gene: 167623852

Centisome position: 44.16

GC content: 44.01

Gene sequence:

>618_bases
ATGATAGGTCGTATTCGCGGATTATTAATAGAGAAGCAAGCACCTGAGGTGTTAGTTGACGTCTCTGGAGTGGGTTATGA
AATTCAAATGCCACTCACTAGCTTTTATGAGCTACCGGAATTAGGTCAAGAAGCGGTTATCTATACACACTTTGTGGTGA
GAGAAGATGCTCAATTGTTATATGGCTTTATTTCTAAACAGGAAAGAAGCTTATTTAGACTACTGATTAAAGCGAATGGC
GTTGGACCAAAGCTGGGTTTGACAATTTTGTCGGGCATGACAGCCAGAGAGTTTGTCGCCTGTGTCGAGCGAGATGATAT
TGCAACCCTTGTAAAACTGCCAGGTGTGGGTAAGAAGACCGCAGAGCGTTTATTGGTTGAGATGCGTGATAAATTAAAGA
GCCTGATGGAAGCATCAGTTGGCTCTGAGCGTGAGTTTATGCTGCAATCAAATTACACCGCGCCAGAAGCTGTCAACACG
GCCGAAGAAGATGCGATTGCCGCGCTGTTATCATTAGGCTATAAGCCAGCTCAAGCGAGCAAAGCGGTTTCATCTGTTTA
TACCGATGGTATGAGCTCTGAAACCCTCATTAAATCCGCACTAAAATCGATGCTTTAA

Upstream 100 bases:

>100_bases
CTGCCGATGCGCTAGGGGTGGCTGTGTGTCATTATCATACTTGTCAAAGTTTGGCAGCCCTTGGCGGCAGAGCCAATGTA
AGAACATATGGACGATATAA

Downstream 100 bases:

>100_bases
GGAAAATAGATGATTGAAGCTGACCGACTCATACATCCTCAGATCATAGACCGCGAAGAAGCAGAAGCTGTTGATCGCGC
TATGCGTCCCAAGATGTTGG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGRIRGLLIEKQAPEVLVDVSGVGYEIQMPLTSFYELPELGQEAVIYTHFVVREDAQLLYGFISKQERSLFRLLIKANG
VGPKLGLTILSGMTAREFVACVERDDIATLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFMLQSNYTAPEAVNT
AEEDAIAALLSLGYKPAQASKAVSSVYTDGMSSETLIKSALKSML

Sequences:

>Translated_205_residues
MIGRIRGLLIEKQAPEVLVDVSGVGYEIQMPLTSFYELPELGQEAVIYTHFVVREDAQLLYGFISKQERSLFRLLIKANG
VGPKLGLTILSGMTAREFVACVERDDIATLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFMLQSNYTAPEAVNT
AEEDAIAALLSLGYKPAQASKAVSSVYTDGMSSETLIKSALKSML
>Mature_205_residues
MIGRIRGLLIEKQAPEVLVDVSGVGYEIQMPLTSFYELPELGQEAVIYTHFVVREDAQLLYGFISKQERSLFRLLIKANG
VGPKLGLTILSGMTAREFVACVERDDIATLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFMLQSNYTAPEAVNT
AEEDAIAALLSLGYKPAQASKAVSSVYTDGMSSETLIKSALKSML

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=60, Blast_Score=253, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_SHEHH (B0TSA6)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674145.1
- ProteinModelPortal:   B0TSA6
- SMR:   B0TSA6
- GeneID:   5905379
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1921
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   SHAL458817:SHAL_1921-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22422; Mature: 22422

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIRGLLIEKQAPEVLVDVSGVGYEIQMPLTSFYELPELGQEAVIYTHFVVREDAQLL
CCCCHHHHEECCCCCCEEEEECCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YGFISKQERSLFRLLIKANGVGPKLGLTILSGMTAREFVACVERDDIATLVKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCCHHH
AERLLVEMRDKLKSLMEASVGSEREFMLQSNYTAPEAVNTAEEDAIAALLSLGYKPAQAS
HHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCHHCCCHHHHHHHHHHHCCCCCHHHH
KAVSSVYTDGMSSETLIKSALKSML
HHHHHHHHCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MIGRIRGLLIEKQAPEVLVDVSGVGYEIQMPLTSFYELPELGQEAVIYTHFVVREDAQLL
CCCCHHHHEECCCCCCEEEEECCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YGFISKQERSLFRLLIKANGVGPKLGLTILSGMTAREFVACVERDDIATLVKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCCHHH
AERLLVEMRDKLKSLMEASVGSEREFMLQSNYTAPEAVNTAEEDAIAALLSLGYKPAQAS
HHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCHHCCCHHHHHHHHHHHCCCCCHHHH
KAVSSVYTDGMSSETLIKSALKSML
HHHHHHHHCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA