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The map label for this gene is ruvB

Identifier: 167623852

GI number: 167623852

Start: 2308754

End: 2309767

Strand: Direct

Name: ruvB

Synonym: Shal_1922

Alternate gene names: 167623852

Gene position: 2308754-2309767 (Clockwise)

Preceding gene: 167623851

Following gene: 167623853

Centisome position: 44.17

GC content: 46.55

Gene sequence:

>1014_bases
ATGATTGAAGCTGACCGACTCATACATCCTCAGATCATAGACCGCGAAGAAGCAGAAGCTGTTGATCGCGCTATGCGTCC
CAAGATGTTGGATGAGTATACTGGCCAAGATGATACTCGTGCACAATTAAAAATCTTTATCGAAGCGGCTCAAAAGCGCG
GCGAAGCGTTAGATCATATGTTGATTTACGGTCCACCAGGTTTAGGTAAAACCACATTGGCGATGATTGTGGCCAATGAA
ATGGGTGTCAATATCAAGTCTACCTCTGGACCCGTGCTTGAAAAAGCAGGCGACTTAGCAGCATTGCTAACAAACCTTGA
GCCAAATGATGTGTTATTTATTGATGAAATCCACCGTCTAAGCCCTGTAGTTGAAGAAATTCTATATCCTGCAATGGAAG
ACTATCAGCTGGATATCATGATTGGCGAAGGCCCTGCAGCGCGCTCAATTAAATTAGACTTACCGCCTTTTACTTTAGTT
GGCGCAACGACACGAGCTGGGGCCTTAACCTCGCCGTTAAGAGCTCGATTTGGCATTCCGCTCAGGCTTGAATTTTATAA
CGTCAAAGATCTGTCCAGTATCGTGGCACGCTCAGCAAAAGTTATGGCGCTTGAAATCGATGACGAAGGCGCTGTCGAAA
TTGCGCGTCGATCTCGTGGTACGCCGCGGATCGCCAATCGCCTGCTTAGACGAGTTCGAGATTTTGCCGAGGTTAAGCAC
AGCGGTGATGTCACTAAAGTAATCGCAGAAGCGGCGCTGGATATGTTAGATGTCGATGCTGAAGGTTTTGACTATATGGA
TAGAAAGCTATTGCTAGCGATTATCGATAAATTTATGGGCGGTCCCGTTGGCTTAGACAACTTGGCTGCAGCCATTGGTG
AAGAGCGAGAAACCATCGAAGATGTACTCGAGCCGTTTTTGATCCAGCAAGGCTTTATACAGAGAACCCCAAGAGGGCGT
ATCGCGACACCAAGAGCTTATAACCACTTTAATATCATTAAGCCAGATGCCTAA

Upstream 100 bases:

>100_bases
AGCTCAAGCGAGCAAAGCGGTTTCATCTGTTTATACCGATGGTATGAGCTCTGAAACCCTCATTAAATCCGCACTAAAAT
CGATGCTTTAAGGAAAATAG

Downstream 100 bases:

>100_bases
AGTTAGTTACAGTCTCTAACGGTATTTGGCTCAAACAATAGGCTTGCTCTGTTGTTAAATGTCTCAAGCCTAAACTGTAG
CTTCTCGCTGTCATCTCTCT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIEADRLIHPQIIDREEAEAVDRAMRPKMLDEYTGQDDTRAQLKIFIEAAQKRGEALDHMLIYGPPGLGKTTLAMIVANE
MGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLV
GATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVARSAKVMALEIDDEGAVEIARRSRGTPRIANRLLRRVRDFAEVKH
SGDVTKVIAEAALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGR
IATPRAYNHFNIIKPDA

Sequences:

>Translated_337_residues
MIEADRLIHPQIIDREEAEAVDRAMRPKMLDEYTGQDDTRAQLKIFIEAAQKRGEALDHMLIYGPPGLGKTTLAMIVANE
MGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLV
GATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVARSAKVMALEIDDEGAVEIARRSRGTPRIANRLLRRVRDFAEVKH
SGDVTKVIAEAALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGR
IATPRAYNHFNIIKPDA
>Mature_337_residues
MIEADRLIHPQIIDREEAEAVDRAMRPKMLDEYTGQDDTRAQLKIFIEAAQKRGEALDHMLIYGPPGLGKTTLAMIVANE
MGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLV
GATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVARSAKVMALEIDDEGAVEIARRSRGTPRIANRLLRRVRDFAEVKH
SGDVTKVIAEAALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGR
IATPRAYNHFNIIKPDA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=336, Percent_Identity=77.6785714285714, Blast_Score=530, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_SHEHH (B0TSA7)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674146.1
- ProteinModelPortal:   B0TSA7
- SMR:   B0TSA7
- GeneID:   5905380
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1922
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   SHAL458817:SHAL_1922-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37295; Mature: 37295

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLIHPQIIDREEAEAVDRAMRPKMLDEYTGQDDTRAQLKIFIEAAQKRGEALDHM
CCCCCCCCCCHHCCHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCE
LIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHCHHHHHHHCCCCCCEEEHHHHHHH
SPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIP
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCC
LRLEFYNVKDLSSIVARSAKVMALEIDDEGAVEIARRSRGTPRIANRLLRRVRDFAEVKH
EEEEEECHHHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SGDVTKVIAEAALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIE
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
DVLEPFLIQQGFIQRTPRGRIATPRAYNHFNIIKPDA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MIEADRLIHPQIIDREEAEAVDRAMRPKMLDEYTGQDDTRAQLKIFIEAAQKRGEALDHM
CCCCCCCCCCHHCCHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCE
LIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHCHHHHHHHCCCCCCEEEHHHHHHH
SPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIP
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCC
LRLEFYNVKDLSSIVARSAKVMALEIDDEGAVEIARRSRGTPRIANRLLRRVRDFAEVKH
EEEEEECHHHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SGDVTKVIAEAALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIE
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
DVLEPFLIQQGFIQRTPRGRIATPRAYNHFNIIKPDA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA