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The map label for this gene is ruvC [H]

Identifier: 167623850

GI number: 167623850

Start: 2307609

End: 2308130

Strand: Direct

Name: ruvC [H]

Synonym: Shal_1920

Alternate gene names: 167623850

Gene position: 2307609-2308130 (Clockwise)

Preceding gene: 167623849

Following gene: 167623851

Centisome position: 44.15

GC content: 48.66

Gene sequence:

>522_bases
ATGGCAATAATTTTAGGGGTCGATCCGGGATCCCGGATCACTGGTTACGGCGTAATTAACTGCGTCGGCCGTCAACAGAT
CTACGTTGGAAGTGGTTGTATTCGAACAAGTTCTGATGAACTTCCTATTCGTTTGAAACAAATATTTGATGGATTGTCAG
AGATTATTAGACAATACCAGCCAGACGAGTTTGCCATTGAGCGCGTGTTTATGGCAAAAAATGCCGATTCAGCGCTTAAA
CTCGGACAAGCTCGCGGCGCAGCTATCGTTGCAGCAACCGCAGCGAATTTACCGGTTGCAGAATACAGCGCGACTCAGAT
TAAAAGCGCGGTAGTCGGTACCGGCCGCGCGCAAAAAGCGCAAGTACAACACATGATTCAACAACTGCTTAAACTCCCCA
GTGCGCCGCAAGCCGATGCTGCCGATGCGCTAGGGGTGGCTGTGTGTCATTATCATACTTGTCAAAGTTTGGCAGCCCTT
GGCGGCAGAGCCAATGTAAGAACATATGGACGATATAAATGA

Upstream 100 bases:

>100_bases
CGCTTAATCGACAACTTAGAAGATCATGATGACGTACAAGAAGTTTATCATAACGCAGAAATTTCTGACGAAGTGATGGA
AGGTCTGGAATAAACCTTAT

Downstream 100 bases:

>100_bases
TAGGTCGTATTCGCGGATTATTAATAGAGAAGCAAGCACCTGAGGTGTTAGTTGACGTCTCTGGAGTGGGTTATGAAATT
CAAATGCCACTCACTAGCTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAIILGVDPGSRITGYGVINCVGRQQIYVGSGCIRTSSDELPIRLKQIFDGLSEIIRQYQPDEFAIERVFMAKNADSALK
LGQARGAAIVAATAANLPVAEYSATQIKSAVVGTGRAQKAQVQHMIQQLLKLPSAPQADAADALGVAVCHYHTCQSLAAL
GGRANVRTYGRYK

Sequences:

>Translated_173_residues
MAIILGVDPGSRITGYGVINCVGRQQIYVGSGCIRTSSDELPIRLKQIFDGLSEIIRQYQPDEFAIERVFMAKNADSALK
LGQARGAAIVAATAANLPVAEYSATQIKSAVVGTGRAQKAQVQHMIQQLLKLPSAPQADAADALGVAVCHYHTCQSLAAL
GGRANVRTYGRYK
>Mature_172_residues
AIILGVDPGSRITGYGVINCVGRQQIYVGSGCIRTSSDELPIRLKQIFDGLSEIIRQYQPDEFAIERVFMAKNADSALKL
GQARGAAIVAATAANLPVAEYSATQIKSAVVGTGRAQKAQVQHMIQQLLKLPSAPQADAADALGVAVCHYHTCQSLAALG
GRANVRTYGRYK

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=156, Percent_Identity=69.2307692307692, Blast_Score=204, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18402; Mature: 18271

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIILGVDPGSRITGYGVINCVGRQQIYVGSGCIRTSSDELPIRLKQIFDGLSEIIRQYQ
CEEEEECCCCCCEECCEEEEECCCCEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHCC
PDEFAIERVFMAKNADSALKLGQARGAAIVAATAANLPVAEYSATQIKSAVVGTGRAQKA
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
QVQHMIQQLLKLPSAPQADAADALGVAVCHYHTCQSLAALGGRANVRTYGRYK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIILGVDPGSRITGYGVINCVGRQQIYVGSGCIRTSSDELPIRLKQIFDGLSEIIRQYQ
EEEEECCCCCCEECCEEEEECCCCEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHCC
PDEFAIERVFMAKNADSALKLGQARGAAIVAATAANLPVAEYSATQIKSAVVGTGRAQKA
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
QVQHMIQQLLKLPSAPQADAADALGVAVCHYHTCQSLAALGGRANVRTYGRYK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA