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The map label for this gene is fabF [H]

Identifier: 167622306

GI number: 167622306

Start: 431309

End: 432556

Strand: Reverse

Name: fabF [H]

Synonym: Shal_0366

Alternate gene names: 167622306

Gene position: 432556-431309 (Counterclockwise)

Preceding gene: 167622307

Following gene: 167622305

Centisome position: 8.28

GC content: 54.17

Gene sequence:

>1248_bases
ATGAGCCAAGCAACTTTTCCTCGCCGCGTCGTGATCACTGGCGTTGGCGGTATTTCAGCCCTCGGCCATGATTGGCCAAC
GATTGCTGACAGCTTGAAAGCGCAGAAAAACTGCGTGGTGCGTATGGACGAATGGGACAGGTTTGCCGATCTGCATACCC
GTTTAGCCGCCCCTATTACTGACTTTGAAGTGCCAAGCCACTACAAACGTAAAAAGATCCGCTCCATGGGGCGGGTGTCG
ATTATGGCGACCCGTGCCAGCGAGCTTGCACTGATTGATGCTAACTTGCTTGATGATCCTGTGGTGACATCGGGTGCCAT
GGGTATCGCTTACGGTTCATCCACGGGCAGTACCGATCCTATCGTCGCATTCGGTGACATGCTTAAAGATGGCGATATGT
CGGGTGTTACCGCCACCAGCTATATCCGCATGATGGCACACACCACGGCGGTTAACGTTGGGGTTTTCTTTGGCCTCAAA
GGCCGAGTGCATACCACCAGCAGCGCCTGTACCTCAGGCAGCCAAGGCATAGGTTATGCCTATGAAGCCATTAAGTATGG
CCAGCAAGACTTAATGCTGGCCGGCGGCGGCGAAGAGCTGTGCCCAACCGAAGCCGTGGTCTTCGATACCTTATTTGCCA
CCAGCACCAAAAATGACACGCCAACCGAGACGCCGCGTCCCTTTGATAAGAGCCGTGATGGCCTAGTGATTGGCGAAGGC
GCCTGCACGCTAGTGCTAGAAGAGCTGGAACATGCCAAGGCTCGCGGCGCCAAGATCTATGCCGAAATAGTTGGCTTTGG
TACCAATGCCGACGGCCTGCATGTGACGCAACCCAATAGTGAAACCATGGAAACTGCGATTCGCTTAGCCCTGAAAGATG
CCGCCATCGACGCCGATAAGATTGGTTATGTGAATGCCCACGGCACCGCGACCGATCGCGGCGATATCGCCGAGACACAG
GCCACGCATGCGGTGTTTGGTGCTAAGCAGCCAATCTCATCACTCAAGAGCTACACCGGCCACACACTGGGGGCTTGCGG
GGCATTAGAGGCTTGGGTGAGCATAGAGATGATGAACGAGGGCTGGTTTGCCCCGACACTGAATCTGACAGAGGTTGATC
CTGAGTGCGGCGAGCTGGATTACATCAAAGATAAGATCCGTCAGCTTGAAACCGATTATGTGATGAGTAATAACTTTGCC
TTCGGCGGAATTAACACCTCGCTGATCTTTAAGCGGTTTAAGAGCTAG

Upstream 100 bases:

>100_bases
TGGGTAAACCCTCAGAGATTGCAGGCCTAGCAAACTACTTGATGTCAGATGACGCCGCCTATATCACCCGCCAAGTGATC
TCGGTGAATGGAGGCATGAT

Downstream 100 bases:

>100_bases
GTTCTAGGTTCTAGGAAAAGCAGGTCCTAGGAAAAGCAAAGACGAACGGCCTACGGCCTTACGGACGTGACTACGTCACT
TACGGAACGCTGCGCTTACG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSQATFPRRVVITGVGGISALGHDWPTIADSLKAQKNCVVRMDEWDRFADLHTRLAAPITDFEVPSHYKRKKIRSMGRVS
IMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDPIVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLK
GRVHTTSSACTSGSQGIGYAYEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPTETPRPFDKSRDGLVIGEG
ACTLVLEELEHAKARGAKIYAEIVGFGTNADGLHVTQPNSETMETAIRLALKDAAIDADKIGYVNAHGTATDRGDIAETQ
ATHAVFGAKQPISSLKSYTGHTLGACGALEAWVSIEMMNEGWFAPTLNLTEVDPECGELDYIKDKIRQLETDYVMSNNFA
FGGINTSLIFKRFKS

Sequences:

>Translated_415_residues
MSQATFPRRVVITGVGGISALGHDWPTIADSLKAQKNCVVRMDEWDRFADLHTRLAAPITDFEVPSHYKRKKIRSMGRVS
IMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDPIVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLK
GRVHTTSSACTSGSQGIGYAYEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPTETPRPFDKSRDGLVIGEG
ACTLVLEELEHAKARGAKIYAEIVGFGTNADGLHVTQPNSETMETAIRLALKDAAIDADKIGYVNAHGTATDRGDIAETQ
ATHAVFGAKQPISSLKSYTGHTLGACGALEAWVSIEMMNEGWFAPTLNLTEVDPECGELDYIKDKIRQLETDYVMSNNFA
FGGINTSLIFKRFKS
>Mature_414_residues
SQATFPRRVVITGVGGISALGHDWPTIADSLKAQKNCVVRMDEWDRFADLHTRLAAPITDFEVPSHYKRKKIRSMGRVSI
MATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDPIVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLKG
RVHTTSSACTSGSQGIGYAYEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPTETPRPFDKSRDGLVIGEGA
CTLVLEELEHAKARGAKIYAEIVGFGTNADGLHVTQPNSETMETAIRLALKDAAIDADKIGYVNAHGTATDRGDIAETQA
THAVFGAKQPISSLKSYTGHTLGACGALEAWVSIEMMNEGWFAPTLNLTEVDPECGELDYIKDKIRQLETDYVMSNNFAF
GGINTSLIFKRFKS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=34.052757793765, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI41872631, Length=281, Percent_Identity=29.8932384341637, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223972627, Length=162, Percent_Identity=37.037037037037, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1787337, Length=420, Percent_Identity=38.0952380952381, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788663, Length=413, Percent_Identity=36.5617433414044, Blast_Score=237, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=31.4009661835749, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=36.7424242424242, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI212642053, Length=348, Percent_Identity=28.448275862069, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=262, Percent_Identity=27.4809160305344, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=444, Percent_Identity=31.981981981982, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24644341, Length=421, Percent_Identity=34.2042755344418, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI221330659, Length=357, Percent_Identity=26.6106442577031, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19920632, Length=357, Percent_Identity=26.6106442577031, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24581345, Length=336, Percent_Identity=26.4880952380952, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44551; Mature: 44420

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQATFPRRVVITGVGGISALGHDWPTIADSLKAQKNCVVRMDEWDRFADLHTRLAAPIT
CCCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCC
DFEVPSHYKRKKIRSMGRVSIMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDP
CCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCC
IVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLKGRVHTTSSACTSGSQGIGYA
EEEEHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCEEECCHHHCCCCCCCHHH
YEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPTETPRPFDKSRDGLVIGEG
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECC
ACTLVLEELEHAKARGAKIYAEIVGFGTNADGLHVTQPNSETMETAIRLALKDAAIDADK
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHH
IGYVNAHGTATDRGDIAETQATHAVFGAKQPISSLKSYTGHTLGACGALEAWVSIEMMNE
CEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECC
GWFAPTLNLTEVDPECGELDYIKDKIRQLETDYVMSNNFAFGGINTSLIFKRFKS
CCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCEEEECCEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
SQATFPRRVVITGVGGISALGHDWPTIADSLKAQKNCVVRMDEWDRFADLHTRLAAPIT
CCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCC
DFEVPSHYKRKKIRSMGRVSIMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDP
CCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCC
IVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLKGRVHTTSSACTSGSQGIGYA
EEEEHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCEEECCHHHCCCCCCCHHH
YEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPTETPRPFDKSRDGLVIGEG
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECC
ACTLVLEELEHAKARGAKIYAEIVGFGTNADGLHVTQPNSETMETAIRLALKDAAIDADK
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHH
IGYVNAHGTATDRGDIAETQATHAVFGAKQPISSLKSYTGHTLGACGALEAWVSIEMMNE
CEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECC
GWFAPTLNLTEVDPECGELDYIKDKIRQLETDYVMSNNFAFGGINTSLIFKRFKS
CCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCEEEECCEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]