BacMap

Definition	Shewanella halifaxensis HAW-EB4 chromosome, complete genome.
Accession	NC_010334
Length	5,226,917

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The map label for this gene is fabG [H]

Identifier: 167622307

GI number: 167622307

Start: 432553

End: 433278

Strand: Reverse

Name: fabG [H]

Synonym: Shal_0367

Alternate gene names: 167622307

Gene position: 433278-432553 (Counterclockwise)

Preceding gene: 167622308

Following gene: 167622306

Centisome position: 8.29

GC content: 52.07

Gene sequence:

>726_bases
ATGACAAAAAGAGTATTAATTACCGGTTCAAGCCGCGGCATAGGCAAAGCTATCGCCCTAAAACTTGCCGCCTCAGGCCA
TGACATTGCGATGCATTTTCATAGCAATCAAACCGCCGCCGATGCCACCAAGGCGGAGCTTGAGCAGTTAGAGATTAAGG
TCAGCTGTCTGCAGTTTGATATCGCCGATAGAGCCGCAGTCAAGCAAGCGATTGAGCAAGATATCGAGCAACACGGCGCC
TATTACGGCGTGGTGCTCAATGCCGGGATCAATGCCGATACCGCGTTTCCGGCGATGACAGAATCTGAGTGGGATAGCGT
GGTGCACACCAACCTAGATGGTTTCTATAACGTTATCCACCCAACCGTTATGCCTATGGTACAGGGTCGTCAAGGCGGAC
GTATCATCACCCTTGCTTCGGTATCGGGCATCGCAGGCAATCGCGGTCAAGTTAACTACAGTGCCTCTAAGGCGGGAATT
ATTGGCGCAACTAAGGCGCTCTCCTTAGAGCTCGCTAAGCGTAAGATCACCGTAAACTGCATCGCCCCTGGGCTTATCGA
AACCGACATGGTCAGCGATATCCCCAAAGAGATGGTCAACAACCTAGTGCCGATGCGCCGCATGGGTAAACCCTCAGAGA
TTGCAGGCCTAGCAAACTACTTGATGTCAGATGACGCCGCCTATATCACCCGCCAAGTGATCTCGGTGAATGGAGGCATG
ATATGA

Upstream 100 bases:

>100_bases
AAAAATACCAAGGTGCTGCGTACCCACTCAGTCATAATTCGCCTCACAAAGGCAACCACAAACAACAGACTAACTAGGGC
GCTACGCAGGGAGTAACAGT

Downstream 100 bases:

>100_bases
GCCAAGCAACTTTTCCTCGCCGCGTCGTGATCACTGGCGTTGGCGGTATTTCAGCCCTCGGCCATGATTGGCCAACGATT
GCTGACAGCTTGAAAGCGCA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTKRVLITGSSRGIGKAIALKLAASGHDIAMHFHSNQTAADATKAELEQLEIKVSCLQFDIADRAAVKQAIEQDIEQHGA
YYGVVLNAGINADTAFPAMTESEWDSVVHTNLDGFYNVIHPTVMPMVQGRQGGRIITLASVSGIAGNRGQVNYSASKAGI
IGATKALSLELAKRKITVNCIAPGLIETDMVSDIPKEMVNNLVPMRRMGKPSEIAGLANYLMSDDAAYITRQVISVNGGM
I

Sequences:

>Translated_241_residues
MTKRVLITGSSRGIGKAIALKLAASGHDIAMHFHSNQTAADATKAELEQLEIKVSCLQFDIADRAAVKQAIEQDIEQHGA
YYGVVLNAGINADTAFPAMTESEWDSVVHTNLDGFYNVIHPTVMPMVQGRQGGRIITLASVSGIAGNRGQVNYSASKAGI
IGATKALSLELAKRKITVNCIAPGLIETDMVSDIPKEMVNNLVPMRRMGKPSEIAGLANYLMSDDAAYITRQVISVNGGM
I
>Mature_240_residues
TKRVLITGSSRGIGKAIALKLAASGHDIAMHFHSNQTAADATKAELEQLEIKVSCLQFDIADRAAVKQAIEQDIEQHGAY
YGVVLNAGINADTAFPAMTESEWDSVVHTNLDGFYNVIHPTVMPMVQGRQGGRIITLASVSGIAGNRGQVNYSASKAGII
GATKALSLELAKRKITVNCIAPGLIETDMVSDIPKEMVNNLVPMRRMGKPSEIAGLANYLMSDDAAYITRQVISVNGGMI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=35.2697095435685, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=32.7935222672065, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=30.4526748971193, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=28.9256198347107, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=28.3400809716599, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI19923817, Length=245, Percent_Identity=26.9387755102041, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4504505, Length=208, Percent_Identity=31.25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI66933014, Length=214, Percent_Identity=28.5046728971963, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4758504, Length=150, Percent_Identity=36, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503301, Length=210, Percent_Identity=27.1428571428571, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=190, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=40.2489626556017, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=35.1020408163265, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=35.9183673469388, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=32.1285140562249, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=29.0983606557377, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.5785123966942, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=26.6393442622951, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=29.6, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.9256198347107, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=24.8062015503876, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=35, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=32.9218106995885, Blast_Score=126, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=30.241935483871, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=30.5220883534137, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=29.0322580645161, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=234, Percent_Identity=31.1965811965812, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=28.8, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=24.2914979757085, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=26.5384615384615, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=24.901185770751, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=31.4516129032258, Blast_Score=95, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=28.494623655914, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=34.020618556701, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=202, Percent_Identity=26.7326732673267, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=210, Percent_Identity=29.5238095238095, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=31.9672131147541, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.9352226720648, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=31.0483870967742, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=26.7716535433071, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=30.0847457627119, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=28.4, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25712; Mature: 25581

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRVLITGSSRGIGKAIALKLAASGHDIAMHFHSNQTAADATKAELEQLEIKVSCLQFD
CCCEEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEEEEEC
IADRAAVKQAIEQDIEQHGAYYGVVLNAGINADTAFPAMTESEWDSVVHTNLDGFYNVIH
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
PTVMPMVQGRQGGRIITLASVSGIAGNRGQVNYSASKAGIIGATKALSLELAKRKITVNC
HHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCEEEHHHHHHHEEHHHEEEEEE
IAPGLIETDMVSDIPKEMVNNLVPMRRMGKPSEIAGLANYLMSDDAAYITRQVISVNGGM
ECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
I
C
>Mature Secondary Structure 
TKRVLITGSSRGIGKAIALKLAASGHDIAMHFHSNQTAADATKAELEQLEIKVSCLQFD
CCEEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEEEEEC
IADRAAVKQAIEQDIEQHGAYYGVVLNAGINADTAFPAMTESEWDSVVHTNLDGFYNVIH
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
PTVMPMVQGRQGGRIITLASVSGIAGNRGQVNYSASKAGIIGATKALSLELAKRKITVNC
HHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCEEEHHHHHHHEEHHHEEEEEE
IAPGLIETDMVSDIPKEMVNNLVPMRRMGKPSEIAGLANYLMSDDAAYITRQVISVNGGM
ECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]