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The map label for this gene is mnmG

Identifier: 167041018

GI number: 167041018

Start: 2451570

End: 2453471

Strand: Reverse

Name: mnmG

Synonym: Teth514_2408

Alternate gene names: 167041018

Gene position: 2453471-2451570 (Counterclockwise)

Preceding gene: 167041019

Following gene: 167041017

Centisome position: 99.85

GC content: 35.38

Gene sequence:

>1902_bases
ATGAATTTTATTGCTGGTGAATACGATGTTGCAGTTGTTGGGTTGGGACATGCGGGCAGTGAGGCTGCTCTCGCTTGTGC
AAGGTTGGGACTTAAAACAGTGGGTTTTGCTGTCAACTTAGATTCTATTGCTTTGATGGCTTGCAATCCTTCTATTGGAG
GCCCTGCCAAGGCTCAGTTGGTGAGAGAGATTGACGCTTTAGGTGGGGAAATGGCTATAAATACAGACAAATCTTTATTA
CAAATTCGTACTTTGAATACCAGTAAAGGCCCTGCTGTAAGGTCTTTGAGAGCACAAGTTGACAAAAAACTTTACCAGAT
GAACATGAAGTACACTTTAGAAAGACAAGAAAACCTTGATATAAAACAGGCGGAAATTGTAGACATTTTGGTAGAAGACA
ACAAAGTTACAGGGGTTGTAACAAAATTAGGTGCGATATATAAATGTAAAGCTTGTATTATTACTACAGGTACCTTCTTA
AAAGGAAGAGTTATAATTGGTGATGTAAGTTTTGACAGTGGACCTAGCGGACTTTTTCCAGCTAATCAGCTTTCTGAGAC
TTTGAAAAGATTAGGTTTTAAATTGATGAGATTTAAAACAGGTACTCCTGCGAGAGTTGATAAAAGAAGTATTGATTTTT
CCAAAATGGAAATACAGCCGGGGGATGAAGTCATTACTCCTTTTTCCTATATGCATGATAAAATCGAAATAGAACAGTTG
CCCTGTTGGCTCACTTATACGAATAAAAGAACTCATGAAATAATAATGGCAAATATTCACCGTTCTCCTCTTTTTAGTGG
TGAAATAACAGGGGTAGGAGTAAGATACTGTCCTTCTATTGAAGATAAAGTTGTAAAGTTTCCTCACAAAGAAAGACATC
AAATTTTTATTGAACCAGAAGGATTAAATACTTATGAAATGTATGTACAAGGTATGTCTTCTAGTTTGCCTGAAGATGTG
CAACTGGAATTTTTGAGGACTGTTCCTGGCCTTGAAAATGTAAGAGTGATGAGGCCAGCTTATGCTATTGAATATGACTG
TATAGACCCAACGCAATTAAAAGCTACTTTAGAATCTAAAAAAATTGAAGGGTTGTACTTTGCAGGACAAGTCAATGGTA
CATCTGGATATGAAGAAGCGGCTGCTCAAGGTTTGATGGCGGGAATAAATGCTGCTATGAAGCTTTTAAACAAACCTTCT
GTGATTTTGGATAGGTCTCAAGCTTATATAGGAGTGTTGATTGATGATTTAGTTACAAAAGGTACAAATGAGCCTTATAG
GATGCTTACTTCGAGAGCTGAATATAGACTTTTATTAAGACAAGATAATGCAGATTTTAGATTGACAGAACTAGGGTATA
AAATCGGCCTTGTAACAGAAGAAAGATATCAAAAATTTTTAAAGAAGAAGATCCAGTTAGAAAAAGAAATGCGAAGACTT
CTTGGCGTTATGATAAAACCTTCTGAGGAAGTCAACAATTTTCTCATATCTAAAGGAAGTACTCCTTTAGTTACAGGAGT
TGACCTTTATACTTTGCTAAAGCGACCTGAAATTGATTATAAGTCTACTAAATTTTTGGATAAAAACAGGCCCGATGATA
TTTTAGACAGTGTTGCTGAACAAATAGACATAAATATTAAATATGAAGGATATATAATGAAACAACTAAGGCAAGTTGAA
CACTTTAAAGCATTAGAAAACAAAAAGATTCCAGAAGATATTGATTATTATCAAATTCATGGTTTAAGCAATGAAGCAAA
AGAAAAATTGACAAAAATAAGACCTACTTCAATTGGACAGGCTTCTCGTATTTCAGGAGTTTCGCCTGCTGATATTTCTG
TGCTTTTAATTTACATGCAGCAGTTAAGGAGAAATAAAGAAGATGAAGAACAAATCGGTTGA

Upstream 100 bases:

>100_bases
CGGCTCTTGACCAATTAGGTAAAATTACTGGAGAGACGGCAACTGAGGATTTAATAAATGAAATTTTTGAGAGATTTTGT
GTGGGAAAGTAGGTGAAAGT

Downstream 100 bases:

>100_bases
AATGCTAATTGAGGGCGCTAAAGAGTGGGGTATATTTTTGGAAATGTTCCATGTGGAACATTTCCAAAAATATTATGCTC
TTTTATTGGAATGGAATCAG

Product: tRNA uridine 5-carboxymethylaminomethyl modification protein GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MNFIAGEYDVAVVGLGHAGSEAALACARLGLKTVGFAVNLDSIALMACNPSIGGPAKAQLVREIDALGGEMAINTDKSLL
QIRTLNTSKGPAVRSLRAQVDKKLYQMNMKYTLERQENLDIKQAEIVDILVEDNKVTGVVTKLGAIYKCKACIITTGTFL
KGRVIIGDVSFDSGPSGLFPANQLSETLKRLGFKLMRFKTGTPARVDKRSIDFSKMEIQPGDEVITPFSYMHDKIEIEQL
PCWLTYTNKRTHEIIMANIHRSPLFSGEITGVGVRYCPSIEDKVVKFPHKERHQIFIEPEGLNTYEMYVQGMSSSLPEDV
QLEFLRTVPGLENVRVMRPAYAIEYDCIDPTQLKATLESKKIEGLYFAGQVNGTSGYEEAAAQGLMAGINAAMKLLNKPS
VILDRSQAYIGVLIDDLVTKGTNEPYRMLTSRAEYRLLLRQDNADFRLTELGYKIGLVTEERYQKFLKKKIQLEKEMRRL
LGVMIKPSEEVNNFLISKGSTPLVTGVDLYTLLKRPEIDYKSTKFLDKNRPDDILDSVAEQIDINIKYEGYIMKQLRQVE
HFKALENKKIPEDIDYYQIHGLSNEAKEKLTKIRPTSIGQASRISGVSPADISVLLIYMQQLRRNKEDEEQIG

Sequences:

>Translated_633_residues
MNFIAGEYDVAVVGLGHAGSEAALACARLGLKTVGFAVNLDSIALMACNPSIGGPAKAQLVREIDALGGEMAINTDKSLL
QIRTLNTSKGPAVRSLRAQVDKKLYQMNMKYTLERQENLDIKQAEIVDILVEDNKVTGVVTKLGAIYKCKACIITTGTFL
KGRVIIGDVSFDSGPSGLFPANQLSETLKRLGFKLMRFKTGTPARVDKRSIDFSKMEIQPGDEVITPFSYMHDKIEIEQL
PCWLTYTNKRTHEIIMANIHRSPLFSGEITGVGVRYCPSIEDKVVKFPHKERHQIFIEPEGLNTYEMYVQGMSSSLPEDV
QLEFLRTVPGLENVRVMRPAYAIEYDCIDPTQLKATLESKKIEGLYFAGQVNGTSGYEEAAAQGLMAGINAAMKLLNKPS
VILDRSQAYIGVLIDDLVTKGTNEPYRMLTSRAEYRLLLRQDNADFRLTELGYKIGLVTEERYQKFLKKKIQLEKEMRRL
LGVMIKPSEEVNNFLISKGSTPLVTGVDLYTLLKRPEIDYKSTKFLDKNRPDDILDSVAEQIDINIKYEGYIMKQLRQVE
HFKALENKKIPEDIDYYQIHGLSNEAKEKLTKIRPTSIGQASRISGVSPADISVLLIYMQQLRRNKEDEEQIG
>Mature_633_residues
MNFIAGEYDVAVVGLGHAGSEAALACARLGLKTVGFAVNLDSIALMACNPSIGGPAKAQLVREIDALGGEMAINTDKSLL
QIRTLNTSKGPAVRSLRAQVDKKLYQMNMKYTLERQENLDIKQAEIVDILVEDNKVTGVVTKLGAIYKCKACIITTGTFL
KGRVIIGDVSFDSGPSGLFPANQLSETLKRLGFKLMRFKTGTPARVDKRSIDFSKMEIQPGDEVITPFSYMHDKIEIEQL
PCWLTYTNKRTHEIIMANIHRSPLFSGEITGVGVRYCPSIEDKVVKFPHKERHQIFIEPEGLNTYEMYVQGMSSSLPEDV
QLEFLRTVPGLENVRVMRPAYAIEYDCIDPTQLKATLESKKIEGLYFAGQVNGTSGYEEAAAQGLMAGINAAMKLLNKPS
VILDRSQAYIGVLIDDLVTKGTNEPYRMLTSRAEYRLLLRQDNADFRLTELGYKIGLVTEERYQKFLKKKIQLEKEMRRL
LGVMIKPSEEVNNFLISKGSTPLVTGVDLYTLLKRPEIDYKSTKFLDKNRPDDILDSVAEQIDINIKYEGYIMKQLRQVE
HFKALENKKIPEDIDYYQIHGLSNEAKEKLTKIRPTSIGQASRISGVSPADISVLLIYMQQLRRNKEDEEQIG

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=639, Percent_Identity=41.0015649452269, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI19882217, Length=664, Percent_Identity=39.4578313253012, Blast_Score=445, Evalue=1e-125,
Organism=Homo sapiens, GI183227703, Length=679, Percent_Identity=38.5861561119293, Blast_Score=440, Evalue=1e-123,
Organism=Escherichia coli, GI2367273, Length=627, Percent_Identity=49.1228070175439, Blast_Score=619, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI17534255, Length=632, Percent_Identity=40.5063291139241, Blast_Score=459, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6321202, Length=617, Percent_Identity=42.4635332252836, Blast_Score=486, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24658174, Length=634, Percent_Identity=42.1135646687697, Blast_Score=464, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_THEP3 (B0K8H8)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001666246.1
- ProteinModelPortal:   B0K8H8
- SMR:   B0K8H8
- GeneID:   5873535
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_2289
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- BioCyc:   TPSE340099:TETH39_2289-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 71061; Mature: 71061

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIAGEYDVAVVGLGHAGSEAALACARLGLKTVGFAVNLDSIALMACNPSIGGPAKAQL
CCCCCCCCCEEEEEECCCCCHHHHHHHHHCHHHHEEEEECCCEEEEEECCCCCCHHHHHH
VREIDALGGEMAINTDKSLLQIRTLNTSKGPAVRSLRAQVDKKLYQMNMKYTLERQENLD
HHHHHHCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
IKQAEIVDILVEDNKVTGVVTKLGAIYKCKACIITTGTFLKGRVIIGDVSFDSGPSGLFP
CCCEEEEEEEEECCCEEHHHHHHCHHHEEEEEEEECCCEEECEEEEEEECCCCCCCCCCC
ANQLSETLKRLGFKLMRFKTGTPARVDKRSIDFSKMEIQPGDEVITPFSYMHDKIEIEQL
HHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEECCHHHHHCEEEHHHC
PCWLTYTNKRTHEIIMANIHRSPLFSGEITGVGVRYCPSIEDKVVKFPHKERHQIFIEPE
CEEEEECCCCCEEEEEEECCCCCCCCCCCCEECEEECCCCCHHHHCCCCCCCCEEEEECC
GLNTYEMYVQGMSSSLPEDVQLEFLRTVPGLENVRVMRPAYAIEYDCIDPTQLKATLESK
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHC
KIEGLYFAGQVNGTSGYEEAAAQGLMAGINAAMKLLNKPSVILDRSQAYIGVLIDDLVTK
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHC
GTNEPYRMLTSRAEYRLLLRQDNADFRLTELGYKIGLVTEERYQKFLKKKIQLEKEMRRL
CCCCHHHHHHCCCCEEEEEEECCCCEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
LGVMIKPSEEVNNFLISKGSTPLVTGVDLYTLLKRPEIDYKSTKFLDKNRPDDILDSVAE
HCEEECCHHHHHHHEECCCCCCEEECHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
QIDINIKYEGYIMKQLRQVEHFKALENKKIPEDIDYYQIHGLSNEAKEKLTKIRPTSIGQ
HEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCC
ASRISGVSPADISVLLIYMQQLRRNKEDEEQIG
HHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MNFIAGEYDVAVVGLGHAGSEAALACARLGLKTVGFAVNLDSIALMACNPSIGGPAKAQL
CCCCCCCCCEEEEEECCCCCHHHHHHHHHCHHHHEEEEECCCEEEEEECCCCCCHHHHHH
VREIDALGGEMAINTDKSLLQIRTLNTSKGPAVRSLRAQVDKKLYQMNMKYTLERQENLD
HHHHHHCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
IKQAEIVDILVEDNKVTGVVTKLGAIYKCKACIITTGTFLKGRVIIGDVSFDSGPSGLFP
CCCEEEEEEEEECCCEEHHHHHHCHHHEEEEEEEECCCEEECEEEEEEECCCCCCCCCCC
ANQLSETLKRLGFKLMRFKTGTPARVDKRSIDFSKMEIQPGDEVITPFSYMHDKIEIEQL
HHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEECCHHHHHCEEEHHHC
PCWLTYTNKRTHEIIMANIHRSPLFSGEITGVGVRYCPSIEDKVVKFPHKERHQIFIEPE
CEEEEECCCCCEEEEEEECCCCCCCCCCCCEECEEECCCCCHHHHCCCCCCCCEEEEECC
GLNTYEMYVQGMSSSLPEDVQLEFLRTVPGLENVRVMRPAYAIEYDCIDPTQLKATLESK
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHC
KIEGLYFAGQVNGTSGYEEAAAQGLMAGINAAMKLLNKPSVILDRSQAYIGVLIDDLVTK
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHC
GTNEPYRMLTSRAEYRLLLRQDNADFRLTELGYKIGLVTEERYQKFLKKKIQLEKEMRRL
CCCCHHHHHHCCCCEEEEEEECCCCEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
LGVMIKPSEEVNNFLISKGSTPLVTGVDLYTLLKRPEIDYKSTKFLDKNRPDDILDSVAE
HCEEECCHHHHHHHEECCCCCCEEECHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
QIDINIKYEGYIMKQLRQVEHFKALENKKIPEDIDYYQIHGLSNEAKEKLTKIRPTSIGQ
HEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCC
ASRISGVSPADISVLLIYMQQLRRNKEDEEQIG
HHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA