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The map label for this gene is trpF [H]

Identifier: 167040496

GI number: 167040496

Start: 1880578

End: 1881189

Strand: Reverse

Name: trpF [H]

Synonym: Teth514_1865

Alternate gene names: 167040496

Gene position: 1881189-1880578 (Counterclockwise)

Preceding gene: 167040497

Following gene: 167040495

Centisome position: 76.56

GC content: 32.35

Gene sequence:

>612_bases
TTGGTAAAAGTAAAGATTTGCGGACTGAGAAGAAAAGAGGATATTGAATATGCCAATGAGCTAAAACCTGATTATGTAGG
ATTTGTCTTTGCAAAAAGCAAAAGACAAATAGAGGTAGAACAGGCTTTAGACCTCATAAGCCTTCTTGATAAAGAGATCA
AAACAGTGGGAGTTTTTGTAAATGAACCAGTGGAAAATGCATTAAAAATAGCTCAAACACTAAATCTCGATGTTTTACAG
TTTCACGGTGATGAAACACAGGATTATATAGATAATTTTAAAAATTTCACAGTGTGGAAGGCAATACGCATAAAAGACAA
AGAAGATTTGGAAAAAACAAAAGAATTTAAAGTAAATAGTTTTGTATTTGATACTTTGACAAAAAACGAATACGGTGGTA
CAGGAAAAACATTTAATTGGGAAGTTTTAAAAGGATTTGAATTGAATGTTCCAATAATTTTGGCAGGAGGGCTAAACGAA
AACAATGTAGAGGAAGCTATAAGAATAGTAAATCCCTATGCTGTTGACGTCTCCAGTGGCGTTGAGACAGAAGGTTATAA
AGATTTTAAAAAAATGAAATCATTTATTGAAAAAGTGAGGGGTATTCGATGA

Upstream 100 bases:

>100_bases
GGAGTAGATGCTGTATTAATTGGTGAGACTTTTATGAAAATCATAGATGATATTGATAAAATCAGCGATTTTGTAAAGGA
GGCCAAGGGAGGAGGATAAA

Downstream 100 bases:

>100_bases
GTGGAAGATTTGGACGTTTTGGAGGTCAGTATGTGCCAGAGACTGTGATGAATGCGCTTATAGAATTAGAGAGGGAATTT
GAAAAAGCTAAACAGGATAA

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MVKVKICGLRRKEDIEYANELKPDYVGFVFAKSKRQIEVEQALDLISLLDKEIKTVGVFVNEPVENALKIAQTLNLDVLQ
FHGDETQDYIDNFKNFTVWKAIRIKDKEDLEKTKEFKVNSFVFDTLTKNEYGGTGKTFNWEVLKGFELNVPIILAGGLNE
NNVEEAIRIVNPYAVDVSSGVETEGYKDFKKMKSFIEKVRGIR

Sequences:

>Translated_203_residues
MVKVKICGLRRKEDIEYANELKPDYVGFVFAKSKRQIEVEQALDLISLLDKEIKTVGVFVNEPVENALKIAQTLNLDVLQ
FHGDETQDYIDNFKNFTVWKAIRIKDKEDLEKTKEFKVNSFVFDTLTKNEYGGTGKTFNWEVLKGFELNVPIILAGGLNE
NNVEEAIRIVNPYAVDVSSGVETEGYKDFKKMKSFIEKVRGIR
>Mature_203_residues
MVKVKICGLRRKEDIEYANELKPDYVGFVFAKSKRQIEVEQALDLISLLDKEIKTVGVFVNEPVENALKIAQTLNLDVLQ
FHGDETQDYIDNFKNFTVWKAIRIKDKEDLEKTKEFKVNSFVFDTLTKNEYGGTGKTFNWEVLKGFELNVPIILAGGLNE
NNVEEAIRIVNPYAVDVSSGVETEGYKDFKKMKSFIEKVRGIR

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=205, Percent_Identity=32.6829268292683, Blast_Score=103, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320210, Length=212, Percent_Identity=32.0754716981132, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23294; Mature: 23294

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVKICGLRRKEDIEYANELKPDYVGFVFAKSKRQIEVEQALDLISLLDKEIKTVGVFV
CEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHEEEEE
NEPVENALKIAQTLNLDVLQFHGDETQDYIDNFKNFTVWKAIRIKDKEDLEKTKEFKVNS
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHH
FVFDTLTKNEYGGTGKTFNWEVLKGFELNVPIILAGGLNENNVEEAIRIVNPYAVDVSSG
EEEEHHCCCCCCCCCCEEEEEEEECEECCCCEEEECCCCCCCHHHHHHHHCCEEEECCCC
VETEGYKDFKKMKSFIEKVRGIR
CCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKVKICGLRRKEDIEYANELKPDYVGFVFAKSKRQIEVEQALDLISLLDKEIKTVGVFV
CEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHEEEEE
NEPVENALKIAQTLNLDVLQFHGDETQDYIDNFKNFTVWKAIRIKDKEDLEKTKEFKVNS
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHH
FVFDTLTKNEYGGTGKTFNWEVLKGFELNVPIILAGGLNENNVEEAIRIVNPYAVDVSSG
EEEEHHCCCCCCCCCCEEEEEEEECEECCCCEEEECCCCCCCHHHHHHHHCCEEEECCCC
VETEGYKDFKKMKSFIEKVRGIR
CCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA