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The map label for this gene is trpB [H]

Identifier: 167040495

GI number: 167040495

Start: 1879406

End: 1880581

Strand: Reverse

Name: trpB [H]

Synonym: Teth514_1864

Alternate gene names: 167040495

Gene position: 1880581-1879406 (Counterclockwise)

Preceding gene: 167040496

Following gene: 167040494

Centisome position: 76.53

GC content: 39.46

Gene sequence:

>1176_bases
ATGAGTGGAAGATTTGGACGTTTTGGAGGTCAGTATGTGCCAGAGACTGTGATGAATGCGCTTATAGAATTAGAGAGGGA
ATTTGAAAAAGCTAAACAGGATAAAGATTTCATGGAAGAATATAGGTATTACTTGAGGGAATATTCAGGAAGGCCTACAC
CTTTGTATTATGCTGAGAATCTTACTAAAAAGCTGGGTGGGGCAAAGATTTATCTAAAGAGGGAAGACCTAAACCACACA
GGAGCCCATAAAATAAACAACGTATTGGGACAGATTTTATTGGCAAAACGGATGAATAAAAAGAGAGTTATAGCTGAGAC
AGGGGCAGGACAGCATGGAGTGGCAACTGCTACAGCTGCTGCAATGTTTGGAATGGAATGCGAAATATTCATGGGAGAAG
AAGATATAAAAAGGCAATCTTTAAATGTCTTTAGAATGAAACTTTTAGGTGCAAAAGTAACACCAGTAAAATCAGGGACG
GGAACCTTAAAAGATGCAGTAAATGAAGCAATAAGGGATTGGGTGACGAATATAAACGATACTTTTTATGTGATAGGTTC
TGTTGTTGGTCCTCATCCTTATCCTACAATGGTGAGAGATTTTCAAAGAGTGATAGGGGATGAAGCAAAAGAACAAATAC
TTCAAAAAGAAGGAAGACTTCCTGATTATGTGATTGCTTGTGTTGGTGGAGGCAGCAATGCAATGGGAATTTTCTATCCC
TTCATTGAAGATAAAGAGGTAAAATTGATAGGAGTAGAAGCAGCCGGAGAAGGGATTGAGACAGGGAAACATGCAGCTGC
AATGGCGAAAGGCTCTGTAGGAGTATTGCACGGCATGATGACTTATCTTTTACAGGATGAAGAGGGGAGAATAATGCCAG
TATACTCTATATCTGCAGGACTGGATTACCCAGGTGTAGGTCCAGAACATGCCTTTTTAAAAGAAAGTAATAGAGCTCAA
TATGTATATGCGACAGACGAAGAAGCATTGGCGGCTTTTATGGATTTATCTCAAACAGAAGGGATAATACCAGCTTTGGA
AAGTGCTCACGCTTTGGCATATGCTATGAAACTGGCTCCAAATTTAACGAAAGACAATATTATCATTGTAAATTTGTCAG
GCAGAGGAGATAAAGACGTAAATACAGTTGCAAAAGTATTGGGGGTGGAGTTATGA

Upstream 100 bases:

>100_bases
TAAATCCCTATGCTGTTGACGTCTCCAGTGGCGTTGAGACAGAAGGTTATAAAGATTTTAAAAAAATGAAATCATTTATT
GAAAAAGTGAGGGGTATTCG

Downstream 100 bases:

>100_bases
ATAGGATTGACAAAAAGTTTGAAGTTTTAAAAGGAGAAGGGCGCAAAGCCTTAATAACCTTTATAACAGCGGGAGACCCG
GATATTGAGACGACTTATGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSGRFGRFGGQYVPETVMNALIELEREFEKAKQDKDFMEEYRYYLREYSGRPTPLYYAENLTKKLGGAKIYLKREDLNHT
GAHKINNVLGQILLAKRMNKKRVIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQSLNVFRMKLLGAKVTPVKSGT
GTLKDAVNEAIRDWVTNINDTFYVIGSVVGPHPYPTMVRDFQRVIGDEAKEQILQKEGRLPDYVIACVGGGSNAMGIFYP
FIEDKEVKLIGVEAAGEGIETGKHAAAMAKGSVGVLHGMMTYLLQDEEGRIMPVYSISAGLDYPGVGPEHAFLKESNRAQ
YVYATDEEALAAFMDLSQTEGIIPALESAHALAYAMKLAPNLTKDNIIIVNLSGRGDKDVNTVAKVLGVEL

Sequences:

>Translated_391_residues
MSGRFGRFGGQYVPETVMNALIELEREFEKAKQDKDFMEEYRYYLREYSGRPTPLYYAENLTKKLGGAKIYLKREDLNHT
GAHKINNVLGQILLAKRMNKKRVIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQSLNVFRMKLLGAKVTPVKSGT
GTLKDAVNEAIRDWVTNINDTFYVIGSVVGPHPYPTMVRDFQRVIGDEAKEQILQKEGRLPDYVIACVGGGSNAMGIFYP
FIEDKEVKLIGVEAAGEGIETGKHAAAMAKGSVGVLHGMMTYLLQDEEGRIMPVYSISAGLDYPGVGPEHAFLKESNRAQ
YVYATDEEALAAFMDLSQTEGIIPALESAHALAYAMKLAPNLTKDNIIIVNLSGRGDKDVNTVAKVLGVEL
>Mature_390_residues
SGRFGRFGGQYVPETVMNALIELEREFEKAKQDKDFMEEYRYYLREYSGRPTPLYYAENLTKKLGGAKIYLKREDLNHTG
AHKINNVLGQILLAKRMNKKRVIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQSLNVFRMKLLGAKVTPVKSGTG
TLKDAVNEAIRDWVTNINDTFYVIGSVVGPHPYPTMVRDFQRVIGDEAKEQILQKEGRLPDYVIACVGGGSNAMGIFYPF
IEDKEVKLIGVEAAGEGIETGKHAAAMAKGSVGVLHGMMTYLLQDEEGRIMPVYSISAGLDYPGVGPEHAFLKESNRAQY
VYATDEEALAAFMDLSQTEGIIPALESAHALAYAMKLAPNLTKDNIIIVNLSGRGDKDVNTVAKVLGVEL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=57.2916666666667, Blast_Score=457, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=59.4805194805195, Blast_Score=482, Evalue=1e-137,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42976; Mature: 42845

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRFGRFGGQYVPETVMNALIELEREFEKAKQDKDFMEEYRYYLREYSGRPTPLYYAEN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEHHHH
LTKKLGGAKIYLKREDLNHTGAHKINNVLGQILLAKRMNKKRVIAETGAGQHGVATATAA
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AMFGMECEIFMGEEDIKRQSLNVFRMKLLGAKVTPVKSGTGTLKDAVNEAIRDWVTNIND
HHHCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TFYVIGSVVGPHPYPTMVRDFQRVIGDEAKEQILQKEGRLPDYVIACVGGGSNAMGIFYP
EEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEE
FIEDKEVKLIGVEAAGEGIETGKHAAAMAKGSVGVLHGMMTYLLQDEEGRIMPVYSISAG
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECC
LDYPGVGPEHAFLKESNRAQYVYATDEEALAAFMDLSQTEGIIPALESAHALAYAMKLAP
CCCCCCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
NLTKDNIIIVNLSGRGDKDVNTVAKVLGVEL
CCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SGRFGRFGGQYVPETVMNALIELEREFEKAKQDKDFMEEYRYYLREYSGRPTPLYYAEN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEHHHH
LTKKLGGAKIYLKREDLNHTGAHKINNVLGQILLAKRMNKKRVIAETGAGQHGVATATAA
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AMFGMECEIFMGEEDIKRQSLNVFRMKLLGAKVTPVKSGTGTLKDAVNEAIRDWVTNIND
HHHCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TFYVIGSVVGPHPYPTMVRDFQRVIGDEAKEQILQKEGRLPDYVIACVGGGSNAMGIFYP
EEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEE
FIEDKEVKLIGVEAAGEGIETGKHAAAMAKGSVGVLHGMMTYLLQDEEGRIMPVYSISAG
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECC
LDYPGVGPEHAFLKESNRAQYVYATDEEALAAFMDLSQTEGIIPALESAHALAYAMKLAP
CCCCCCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
NLTKDNIIIVNLSGRGDKDVNTVAKVLGVEL
CCCCCCEEEEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA