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The map label for this gene is ymxG [H]

Identifier: 167040274

GI number: 167040274

Start: 1653806

End: 1655062

Strand: Reverse

Name: ymxG [H]

Synonym: Teth514_1637

Alternate gene names: 167040274

Gene position: 1655062-1653806 (Counterclockwise)

Preceding gene: 167040275

Following gene: 167040273

Centisome position: 67.35

GC content: 30.71

Gene sequence:

>1257_bases
ATGTACGAACAAAAGATTATTGAAGGAGTAAAAGTTGTAACTTGTAAAATTCCTCACGCATATTCTGTATACATAGGGAT
ATGGATTAAAGCAGGCTCTATGTACGAACATAAAACTATAAATGGAATATCTCATTTTATAGAACACATGGTTTTTAAAG
GTTCTAAGTTAAGAAGCGCAAAGCAAATTGCGGAAGAAACGGATAGTATTGGTGGGCAGTTAAACGGCTTTACTGAAAAA
GAAAGTACCTGTTTTTATATAAAAGTCTTAAATACTCACGTAAAACAAGGTCTTGATATACTTTTTGATATGGTATTTAA
CCCTGCTTTTAAAGAAGAAGACATAGAGAAGGAAAAGCAAGTCATCTTTGAAGAAATATTGACAGAATTAGATTCTCCTG
AAGACGTAGCTTACAACCTTTTAGCAAAAACAATATGGAACGGACATCCCTTGTCTTTTCCTGTACTTGGTACTTTTTCT
ACTGTTAAGAAGCTAAACAAAGGACAGATTGTAGATTATTATAATTCCCATTATAACAAAGATAACATAGTCATCTCGAT
AGCTGGAAATTTTGGCGATGATATCTATGAAATACTGCAAAAATATTTATCAAAAATTCAAAAAACTAATGTTATTTCTC
AATTAACTTCTCCAATTTGGCATAAAAACAAAGCTTTTTATGAAAAAGATTTTGAACAGGTAAATTTATGTATTGGTTTG
CCTGGGATAACTTACGACTTAAGGAAAGTATATGCTTTAGCTATCATTAATAATGCTTTTGGTGGAGGAATGAGTTCAAG
ACTATTTCAAAAAATAAGAGAAGATAAGGGATTGGTTTACTCGATTTATTCTTATCCTTCTACCTATCACCATGCTGGGG
TTTTTTCTATTTTTGCTAGTATGAACGCTAATAATTTTAGAAAGGTATATAACTTAATTTTAAAAGAAATGGAAGAAGTG
CATTCAAAAGGCTTAGCAAAAGAAGAGATTGATAAATTTAAAGAACAACTTCGCATAAACGTATTAATGGATTTAGACAG
TATAAGCAGTAGAATGAGCACAATAGGAAAATCCATGCTTTTATTTAACAAAGTGTATACTGTAGAGGAAATACTTCAGA
CAATAGATAACTTGACTTACGACGAAATAAATGATTTAGCTAAAAAAATTATAAATCCTGCTGACATGAGCATAGCCGTG
GTTGGAAAATTAAACAAAAGAGATAAAGGGTGGTTAGAAAATGTCAATAATACTTAA

Upstream 100 bases:

>100_bases
CTTAAAGAAAAAGGTTATAAAATAACTAAAGTATCGGAAGTAATTGTAGATAACAATTAAATTTGCTATAATAATAATTA
AATTTGCAAAGGAGGATAAA

Downstream 100 bases:

>100_bases
GATTAAAAAAACTGATGATGCTAAAGACTTACCTTTGCCTGCTTATATGAGTGAAGGAGCCGCTGGGATGGATTTATATG
CTAATGTTAAAGAGGAAGTC

Product: processing peptidase

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MYEQKIIEGVKVVTCKIPHAYSVYIGIWIKAGSMYEHKTINGISHFIEHMVFKGSKLRSAKQIAEETDSIGGQLNGFTEK
ESTCFYIKVLNTHVKQGLDILFDMVFNPAFKEEDIEKEKQVIFEEILTELDSPEDVAYNLLAKTIWNGHPLSFPVLGTFS
TVKKLNKGQIVDYYNSHYNKDNIVISIAGNFGDDIYEILQKYLSKIQKTNVISQLTSPIWHKNKAFYEKDFEQVNLCIGL
PGITYDLRKVYALAIINNAFGGGMSSRLFQKIREDKGLVYSIYSYPSTYHHAGVFSIFASMNANNFRKVYNLILKEMEEV
HSKGLAKEEIDKFKEQLRINVLMDLDSISSRMSTIGKSMLLFNKVYTVEEILQTIDNLTYDEINDLAKKIINPADMSIAV
VGKLNKRDKGWLENVNNT

Sequences:

>Translated_418_residues
MYEQKIIEGVKVVTCKIPHAYSVYIGIWIKAGSMYEHKTINGISHFIEHMVFKGSKLRSAKQIAEETDSIGGQLNGFTEK
ESTCFYIKVLNTHVKQGLDILFDMVFNPAFKEEDIEKEKQVIFEEILTELDSPEDVAYNLLAKTIWNGHPLSFPVLGTFS
TVKKLNKGQIVDYYNSHYNKDNIVISIAGNFGDDIYEILQKYLSKIQKTNVISQLTSPIWHKNKAFYEKDFEQVNLCIGL
PGITYDLRKVYALAIINNAFGGGMSSRLFQKIREDKGLVYSIYSYPSTYHHAGVFSIFASMNANNFRKVYNLILKEMEEV
HSKGLAKEEIDKFKEQLRINVLMDLDSISSRMSTIGKSMLLFNKVYTVEEILQTIDNLTYDEINDLAKKIINPADMSIAV
VGKLNKRDKGWLENVNNT
>Mature_418_residues
MYEQKIIEGVKVVTCKIPHAYSVYIGIWIKAGSMYEHKTINGISHFIEHMVFKGSKLRSAKQIAEETDSIGGQLNGFTEK
ESTCFYIKVLNTHVKQGLDILFDMVFNPAFKEEDIEKEKQVIFEEILTELDSPEDVAYNLLAKTIWNGHPLSFPVLGTFS
TVKKLNKGQIVDYYNSHYNKDNIVISIAGNFGDDIYEILQKYLSKIQKTNVISQLTSPIWHKNKAFYEKDFEQVNLCIGL
PGITYDLRKVYALAIINNAFGGGMSSRLFQKIREDKGLVYSIYSYPSTYHHAGVFSIFASMNANNFRKVYNLILKEMEEV
HSKGLAKEEIDKFKEQLRINVLMDLDSISSRMSTIGKSMLLFNKVYTVEEILQTIDNLTYDEINDLAKKIINPADMSIAV
VGKLNKRDKGWLENVNNT

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=398, Percent_Identity=26.3819095477387, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI46593007, Length=398, Percent_Identity=26.6331658291457, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI24308013, Length=416, Percent_Identity=22.1153846153846, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1787770, Length=365, Percent_Identity=20.2739726027397, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=393, Percent_Identity=25.4452926208651, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17553678, Length=409, Percent_Identity=22.9828850855746, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323192, Length=398, Percent_Identity=27.8894472361809, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321813, Length=443, Percent_Identity=23.4762979683973, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21357875, Length=411, Percent_Identity=26.0340632603406, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24646943, Length=411, Percent_Identity=26.0340632603406, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI19921772, Length=414, Percent_Identity=19.3236714975845, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24667786, Length=180, Percent_Identity=27.2222222222222, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641429, Length=220, Percent_Identity=24.5454545454545, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47765; Mature: 47765

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEQKIIEGVKVVTCKIPHAYSVYIGIWIKAGSMYEHKTINGISHFIEHMVFKGSKLRSA
CCHHHHHCCCEEEEEECCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
KQIAEETDSIGGQLNGFTEKESTCFYIKVLNTHVKQGLDILFDMVFNPAFKEEDIEKEKQ
HHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VIFEEILTELDSPEDVAYNLLAKTIWNGHPLSFPVLGTFSTVKKLNKGQIVDYYNSHYNK
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCC
DNIVISIAGNFGDDIYEILQKYLSKIQKTNVISQLTSPIWHKNKAFYEKDFEQVNLCIGL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEC
PGITYDLRKVYALAIINNAFGGGMSSRLFQKIREDKGLVYSIYSYPSTYHHAGVFSIFAS
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
MNANNFRKVYNLILKEMEEVHSKGLAKEEIDKFKEQLRINVLMDLDSISSRMSTIGKSML
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHH
LFNKVYTVEEILQTIDNLTYDEINDLAKKIINPADMSIAVVGKLNKRDKGWLENVNNT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHCCCCCC
>Mature Secondary Structure
MYEQKIIEGVKVVTCKIPHAYSVYIGIWIKAGSMYEHKTINGISHFIEHMVFKGSKLRSA
CCHHHHHCCCEEEEEECCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
KQIAEETDSIGGQLNGFTEKESTCFYIKVLNTHVKQGLDILFDMVFNPAFKEEDIEKEKQ
HHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VIFEEILTELDSPEDVAYNLLAKTIWNGHPLSFPVLGTFSTVKKLNKGQIVDYYNSHYNK
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCC
DNIVISIAGNFGDDIYEILQKYLSKIQKTNVISQLTSPIWHKNKAFYEKDFEQVNLCIGL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEC
PGITYDLRKVYALAIINNAFGGGMSSRLFQKIREDKGLVYSIYSYPSTYHHAGVFSIFAS
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
MNANNFRKVYNLILKEMEEVHSKGLAKEEIDKFKEQLRINVLMDLDSISSRMSTIGKSML
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHH
LFNKVYTVEEILQTIDNLTYDEINDLAKKIINPADMSIAVVGKLNKRDKGWLENVNNT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]