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The map label for this gene is plsC [H]

Identifier: 167040242

GI number: 167040242

Start: 1621423

End: 1622001

Strand: Direct

Name: plsC [H]

Synonym: Teth514_1605

Alternate gene names: 167040242

Gene position: 1621423-1622001 (Clockwise)

Preceding gene: 167040241

Following gene: 167040243

Centisome position: 65.99

GC content: 33.68

Gene sequence:

>579_bases
ATGTTTTATTATATTGCTAAAGTTATTGTACGGACAATCATAAAAGTGATATTTAGAATAGAAATACGAGGACTTGAAAA
TATCCCTAAAAAAGGTCCGGTAATCATATGTTCTAACCATATAAGTCTTTTAGATCCTCCTGTCATAGGAGCCCTTTTAA
ATAGGCGAATATACTTTATGGCAAAAGAAGAGCTTTTTAAAAATCCTTTTTTAAGGCTTCTTTTAGGGACAGGCTTAGGG
GCTTTTCCCGTTAAAAGAGGTACTGCTGATTTATCAGCTATTAAAACTGCTTTAACTTACTTAAAAAAAGGAAGAGCAAT
TGGAATTTTTCCTGAAGGTACAAGAAGTAAAACTGGTCAGCTTCAAAAGGCTGAGCCAGGAGTTGCTATGTTGGCAATTA
AGGGGAATGCCCCAGTAGTGCCTATAGGAATTAAAGGGAGATATCGTCTTTTTTCTAAGATTATTATAAATATCGGTAAA
CCAATAAGTTTTGTAAAATATGCAAATTCTAAACTTTCCTCTAAGCAACTTTCTGTTATTGGGGAAGAAATAATGCAGGA
AATTGCAAAATTGCTGTAG

Upstream 100 bases:

>100_bases
AAGATTCTATTGTCATTGATACTACGTATCTTTCAGAAGAAGAAGTTGTAGAAAAACTGTACAATATCATAAAGGAAGGA
TTAAAAGGGGAAATTTAAGT

Downstream 100 bases:

>100_bases
GAGGTAAAGAATGAAAATATTGATTGCTGAGTATGCAGGTTTCTGCTTTGGAGTAAAAAGAGCTATTGAAACTGCATATC
AGGAAATTGAAAAAGGTGAT

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MFYYIAKVIVRTIIKVIFRIEIRGLENIPKKGPVIICSNHISLLDPPVIGALLNRRIYFMAKEELFKNPFLRLLLGTGLG
AFPVKRGTADLSAIKTALTYLKKGRAIGIFPEGTRSKTGQLQKAEPGVAMLAIKGNAPVVPIGIKGRYRLFSKIIINIGK
PISFVKYANSKLSSKQLSVIGEEIMQEIAKLL

Sequences:

>Translated_192_residues
MFYYIAKVIVRTIIKVIFRIEIRGLENIPKKGPVIICSNHISLLDPPVIGALLNRRIYFMAKEELFKNPFLRLLLGTGLG
AFPVKRGTADLSAIKTALTYLKKGRAIGIFPEGTRSKTGQLQKAEPGVAMLAIKGNAPVVPIGIKGRYRLFSKIIINIGK
PISFVKYANSKLSSKQLSVIGEEIMQEIAKLL
>Mature_192_residues
MFYYIAKVIVRTIIKVIFRIEIRGLENIPKKGPVIICSNHISLLDPPVIGALLNRRIYFMAKEELFKNPFLRLLLGTGLG
AFPVKRGTADLSAIKTALTYLKKGRAIGIFPEGTRSKTGQLQKAEPGVAMLAIKGNAPVVPIGIKGRYRLFSKIIINIGK
PISFVKYANSKLSSKQLSVIGEEIMQEIAKLL

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789201, Length=189, Percent_Identity=26.4550264550265, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=212, Percent_Identity=29.7169811320755, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 21206; Mature: 21206

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYYIAKVIVRTIIKVIFRIEIRGLENIPKKGPVIICSNHISLLDPPVIGALLNRRIYFM
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCEEEE
AKEELFKNPFLRLLLGTGLGAFPVKRGTADLSAIKTALTYLKKGRAIGIFPEGTRSKTGQ
EHHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
LQKAEPGVAMLAIKGNAPVVPIGIKGRYRLFSKIIINIGKPISFVKYANSKLSSKQLSVI
CCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHH
GEEIMQEIAKLL
HHHHHHHHHHHC
>Mature Secondary Structure
MFYYIAKVIVRTIIKVIFRIEIRGLENIPKKGPVIICSNHISLLDPPVIGALLNRRIYFM
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCEEEE
AKEELFKNPFLRLLLGTGLGAFPVKRGTADLSAIKTALTYLKKGRAIGIFPEGTRSKTGQ
EHHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
LQKAEPGVAMLAIKGNAPVVPIGIKGRYRLFSKIIINIGKPISFVKYANSKLSSKQLSVI
CCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHH
GEEIMQEIAKLL
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]