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The map label for this gene is hprK

Identifier: 167039709

GI number: 167039709

Start: 1097027

End: 1097944

Strand: Direct

Name: hprK

Synonym: Teth514_1059

Alternate gene names: 167039709

Gene position: 1097027-1097944 (Clockwise)

Preceding gene: 167039707

Following gene: 167039710

Centisome position: 44.64

GC content: 35.08

Gene sequence:

>918_bases
GTGGATAAGATTCCTGTTGAAACTTTGATAAAGGATTTAAATTTGGAAGTTATTGTTGAGGCCAAAAATAATAAAATAGA
TATAACTACAAGTGATGTAAATAGGCCGGGCTTACAATTTTCCGGCTTTTATGAGCATTTTGCTTACGAAAGAGTGCAAA
TCATTGGAAAAGTTGAAACAACTTTTATAGAACAGTTGCCAGATGATGTATTAGCTGAAAGAGCAGACAGGTTTTTTAAT
TATCCCATTCCCTGTCTTATTGTAACGAGAGATTTAAATATTCGTCAAGAGATCATAGATGCTGCGCAAAAACACGATAG
ATACCTTTTAAGGACAAAAGAAGCTTCTACCAAGTTTATAAATAGATTAATTAATTACCTTGATGAAAAGTTAGCACCAC
AAATTACTATTCACGGAGACCTTGTAGATGTGTATGGTATAGGTGTTCTTTTATTAGGAGAAAGTGGCATAGGTAAAAGT
GAAACGGCATTAGAGCTAATCAAAAGGGGACACCGACTGGTTGCTGATGATGCGGTGGAAATCAGCAAGATAAGTGAGGA
CAAGCTTCAAGGGAGTTCACCTGAGATAATAAGGCATTTTATTGAAATAAGAGGTATTGGCATACTTGACATAAAGACAT
TGTATGGTGTGGGTTCTGTTAGAAATTCTATGAACATAGACTTAGTTATTCAATTGGAAGAATGGGACGAAGATAAGTAC
TACGACAGGTTAGGATTAGAAGACGATTATATCAAATTTTTAGATGTCAAAGTTCCAAAGCTTACTATACCTGTAAGACC
AGGAAGAAATCTCGCGATAATAGTAGAAGTAGCAGCGATGAACCACAGGCAAAAACAAATGGGATACAACGCTGCTCACG
AACTTAACAAAAAATTATTAAAACAAATAGGGAATTAA

Upstream 100 bases:

>100_bases
CATCTTCCAAGAAGAAAAGGTTTTGTCTATTTACTTATTTTACATTAAATAATATAATTGAATTAAATGCAGCGTTTTGT
TGCTGGCTGGAGGTGAAAAA

Downstream 100 bases:

>100_bases
AGGGAGAGGATAAAGTTGAAGTTAGTTTTGGATACTCACACTCACACAATTTCCAGCGGTCACGCTTACAGCACTATTAC
AGAAAACGCAAGGGAGGCTT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDKIPVETLIKDLNLEVIVEAKNNKIDITTSDVNRPGLQFSGFYEHFAYERVQIIGKVETTFIEQLPDDVLAERADRFFN
YPIPCLIVTRDLNIRQEIIDAAQKHDRYLLRTKEASTKFINRLINYLDEKLAPQITIHGDLVDVYGIGVLLLGESGIGKS
ETALELIKRGHRLVADDAVEISKISEDKLQGSSPEIIRHFIEIRGIGILDIKTLYGVGSVRNSMNIDLVIQLEEWDEDKY
YDRLGLEDDYIKFLDVKVPKLTIPVRPGRNLAIIVEVAAMNHRQKQMGYNAAHELNKKLLKQIGN

Sequences:

>Translated_305_residues
MDKIPVETLIKDLNLEVIVEAKNNKIDITTSDVNRPGLQFSGFYEHFAYERVQIIGKVETTFIEQLPDDVLAERADRFFN
YPIPCLIVTRDLNIRQEIIDAAQKHDRYLLRTKEASTKFINRLINYLDEKLAPQITIHGDLVDVYGIGVLLLGESGIGKS
ETALELIKRGHRLVADDAVEISKISEDKLQGSSPEIIRHFIEIRGIGILDIKTLYGVGSVRNSMNIDLVIQLEEWDEDKY
YDRLGLEDDYIKFLDVKVPKLTIPVRPGRNLAIIVEVAAMNHRQKQMGYNAAHELNKKLLKQIGN
>Mature_305_residues
MDKIPVETLIKDLNLEVIVEAKNNKIDITTSDVNRPGLQFSGFYEHFAYERVQIIGKVETTFIEQLPDDVLAERADRFFN
YPIPCLIVTRDLNIRQEIIDAAQKHDRYLLRTKEASTKFINRLINYLDEKLAPQITIHGDLVDVYGIGVLLLGESGIGKS
ETALELIKRGHRLVADDAVEISKISEDKLQGSSPEIIRHFIEIRGIGILDIKTLYGVGSVRNSMNIDLVIQLEEWDEDKY
YDRLGLEDDYIKFLDVKVPKLTIPVRPGRNLAIIVEVAAMNHRQKQMGYNAAHELNKKLLKQIGN

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_THEP3 (B0K793)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001664576.1
- ProteinModelPortal:   B0K793
- SMR:   B0K793
- GeneID:   5873964
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_0576
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   TPSE340099:TETH39_0576-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34779; Mature: 34779

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: ACT_SITE 138-138 ACT_SITE 159-159 ACT_SITE 177-177 ACT_SITE 243-243

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIPVETLIKDLNLEVIVEAKNNKIDITTSDVNRPGLQFSGFYEHFAYERVQIIGKVET
CCCCCHHHHHHHCCEEEEEEECCCEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHH
TFIEQLPDDVLAERADRFFNYPIPCLIVTRDLNIRQEIIDAAQKHDRYLLRTKEASTKFI
HHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECHHHHHHH
NRLINYLDEKLAPQITIHGDLVDVYGIGVLLLGESGIGKSETALELIKRGHRLVADDAVE
HHHHHHHHHHHCCEEEEECCEEHHHCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCHH
ISKISEDKLQGSSPEIIRHFIEIRGIGILDIKTLYGVGSVRNSMNIDLVIQLEEWDEDKY
HHHCCHHHCCCCCHHHHHHHHHHCCCCEEEHHHHHCCHHHCCCCCEEEEEEEECCCCCHH
YDRLGLEDDYIKFLDVKVPKLTIPVRPGRNLAIIVEVAAMNHRQKQMGYNAAHELNKKLL
HHHCCCCCHHEEEEEEECCEEEEECCCCCCEEEEEEEECCCCHHHHHCCHHHHHHHHHHH
KQIGN
HHHCC
>Mature Secondary Structure
MDKIPVETLIKDLNLEVIVEAKNNKIDITTSDVNRPGLQFSGFYEHFAYERVQIIGKVET
CCCCCHHHHHHHCCEEEEEEECCCEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHH
TFIEQLPDDVLAERADRFFNYPIPCLIVTRDLNIRQEIIDAAQKHDRYLLRTKEASTKFI
HHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECHHHHHHH
NRLINYLDEKLAPQITIHGDLVDVYGIGVLLLGESGIGKSETALELIKRGHRLVADDAVE
HHHHHHHHHHHCCEEEEECCEEHHHCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCHH
ISKISEDKLQGSSPEIIRHFIEIRGIGILDIKTLYGVGSVRNSMNIDLVIQLEEWDEDKY
HHHCCHHHCCCCCHHHHHHHHHHCCCCEEEHHHHHCCHHHCCCCCEEEEEEEECCCCCHH
YDRLGLEDDYIKFLDVKVPKLTIPVRPGRNLAIIVEVAAMNHRQKQMGYNAAHELNKKLL
HHHCCCCCHHEEEEEEECCEEEEECCCCCCEEEEEEEECCCCHHHHHCCHHHHHHHHHHH
KQIGN
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA