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The map label for this gene is ubiE [H]

Identifier: 163845177

GI number: 163845177

Start: 1040028

End: 1040837

Strand: Reverse

Name: ubiE [H]

Synonym: BSUIS_B1061

Alternate gene names: 163845177

Gene position: 1040837-1040028 (Counterclockwise)

Preceding gene: 163845180

Following gene: 163845176

Centisome position: 74.3

GC content: 56.79

Gene sequence:

>810_bases
ATGAGCCAGCAAAACGGCAATGTGAACCGCGTGGGCGCACAAGATCGTGTTGGTGCATCGGGCGGCATGGAGCATTCATT
CGGCTTCAAGGCGGTGGACGAAAACGAAAAGCAGGGGCTGGTCAACGACGTTTTCCATAAGGTTGCCAAGCGTTACGACA
TCATGAACGATCTGATGTCTGCCGGTATGCACCGCGTCTGGAAAGATGCGATGGTGGCCTGGCTTGCGCCCTCGAAGCGC
CCCGGCTGGACCTCGCTTGATGTTGCAGGCGGCACGGGCGACATTGCCTTTCGCATCGTGGAAGCTTCGGGCCGCCAGGC
ACATGTCACCATTCTCGATATCAACGGGTCGATGCTCGGCGTCGGGCGTGAACGCGCCATCAAGAAGGGCCTCATCGACA
ATCTTGAATTCGTCGAGGCCAATGCGGAGGAATTGCCGTTCGAGGACAATAGTTTCGATGCCTATACGATCGCCTTCGGC
ATTCGCAATGTGCCGCATATCGACAAGGCGCTGAGCGAGGCTTATTGCGTGCTCAAGCCGGGCGGGCGTTTCCTGTGCCT
TGAATTTTCGGAAGTTGAATTGCCGGTTCTCGACAAGGTTTATGACGAATGGTCGTTCCGGGCCATTCCGCGCATCGGCA
AGATGATTACAGGTGACGCGGACTCCTATAGCTATCTGGTCGAATCGATCCGCAAATTCCCCAAGCAGCAGGATTTTGCC
GCGATGATCGAGAAGGCCGGTTTCGAGCGCGTCAGCTATCGCAATTTCACCGGCGGCATTGCCGCGCTCCATTCCGGCTG
GAAGCTTTGA

Upstream 100 bases:

>100_bases
CTGATCCAAAAGTCACCATGCCGGGGCTATACGTGGCTTGCCGCTTTTTGATTCAGGCAGCAGTATCGTTTTCGTAATAA
ACCAAGAAGCAGGATGAGCT

Downstream 100 bases:

>100_bases
TCGTGCCTGTGATGAGTTCGGGTCGCAACCAGCGTGAGGCATCGGCGCATGAGTAACCTTTCCGCCGTTTTCCGGCTGAT
GCGGGCCGGATGGATATTGA

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMSAGMHRVWKDAMVAWLAPSKR
PGWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFG
IRNVPHIDKALSEAYCVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFA
AMIEKAGFERVSYRNFTGGIAALHSGWKL

Sequences:

>Translated_269_residues
MSQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMSAGMHRVWKDAMVAWLAPSKR
PGWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFG
IRNVPHIDKALSEAYCVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFA
AMIEKAGFERVSYRNFTGGIAALHSGWKL
>Mature_268_residues
SQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMSAGMHRVWKDAMVAWLAPSKRP
GWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFGI
RNVPHIDKALSEAYCVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFAA
MIEKAGFERVSYRNFTGGIAALHSGWKL

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=293, Percent_Identity=48.8054607508532, Blast_Score=272, Evalue=2e-73,
Organism=Escherichia coli, GI48994983, Length=243, Percent_Identity=51.440329218107, Blast_Score=254, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17557039, Length=264, Percent_Identity=49.2424242424242, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI25143945, Length=101, Percent_Identity=30.6930693069307, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323526, Length=256, Percent_Identity=46.875, Blast_Score=225, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24641702, Length=279, Percent_Identity=50.5376344086022, Blast_Score=272, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 29845; Mature: 29714

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS01183 UBIE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMS
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AGMHRVWKDAMVAWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLG
HHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEEECCCCEEEEEEEEECCCEEC
VGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVPHIDKALSEAYCVLKP
CCHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCEEEECC
GGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFA
CCCEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHH
AMIEKAGFERVSYRNFTGGIAALHSGWKL
HHHHHHCCHHHCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
SQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMS
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AGMHRVWKDAMVAWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLG
HHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEEECCCCEEEEEEEEECCCEEC
VGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVPHIDKALSEAYCVLKP
CCHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCEEEECC
GGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFA
CCCEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHH
AMIEKAGFERVSYRNFTGGIAALHSGWKL
HHHHHHCCHHHCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA