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The map label for this gene is yicO [C]

Identifier: 162448207

GI number: 162448207

Start: 1432752

End: 1434119

Strand: Direct

Name: yicO [C]

Synonym: ACL_1371

Alternate gene names: 162448207

Gene position: 1432752-1434119 (Clockwise)

Preceding gene: 162448206

Following gene: 162448214

Centisome position: 95.71

GC content: 35.45

Gene sequence:

>1368_bases
ATGAATCAAATTAAAAAGTTCTTCAAGTTTGAAGAACGCGGCGCGTCTTTCCGTGCAGAAATTATTGGTGGCATTGTCAC
ATTCTTAGCGATGAGCTATATTTTAGTCGTAAATCCTGGTATTGCATCTGGATTATGGTCTGGAGAGGCTGGTATTCCTT
ATGGTGGTGTATTCTTTGCAACTGTAGTTGGTGCATTTATCGCAACCATGGTGATGGCTTTACTAGCAAACCTACCCATT
GGTTTAGCACCTGGTATGGGTGTGAATGCATTCTTTGTAGGTGTCATTATTGGCCAATATGGCTACACATGGCAAGAAGC
ACTTGCATTGAGTTTTATTGGTGGACTTTTATTCTTACTTATCTCATTAACACCATTAAGACGTACCCTTATACAAGCAA
TCCCACAAGATCTTAAAGCTGCAATTGGTGTGGGTATTGGTTTCTTTATTGCTTTTGTAGGTTTACGTTTATCCGGTGTT
TTTGTTTGGAATGGTCAATTACAGTTAGGTGATCTTACAAGCCCTTCTGTCTTACTTGGACTATTTAGTGTTGTTTTAAT
CTTCATTGTACACTCTTTAAAACACGGTATTTCTAAATTCTCATTTATTATATCTATCGTTGTTACAGCACTTGTTGGGT
TACTCTTAGGTCAACTTGGTGTTCAAAATATGCCATCCTTTGGTGAATTCAATTATGATGCATTTGCAGATATTCCCAAT
GTTGCTTTTGTTGGTGTATTTGAAGGCTTTAAAACTGTATTTACACAACCAGTATTTACTACACTATTCTTAGTATTTGC
TCTCTTATTTGTGGATATTTTCGATACTGCTGGTACTTTAGTAGCTGTTGGTAAATCTGCTGGTTTAGAAGATAGTGAAG
GTAATATTCCTAATTTAGATAAAGCACTACTTGCTGACTCTATTGGTACACTTGTTTCTTCTACACTAGGTACACCTGAA
ATTACTTCTTATGTAGAATCTACAACAGGGGTTGAAGCTGGTGCTAAAACAGGATTCTCATCTGTTGTGGTTGCACTATT
ATTCTTATTATCTTTAGCATTATTTCCAATCTTTAATATCTTTACACACTCTTCTGTAACACTAGGTGCACTTGTTTTAG
TTGGTGTGTTAATGTCTCAACAATTAAAAGAAATTGATTGGTCAAACATGACTTCTGCTATTACAGCATTTGTTGTGATT
GTTGGTATGATTTTTACATCAAGTATTGCTGATGGTATCGCATTTGGATTTATCGTCTATACTTTAATTAAACTTGTTCG
TGGTGAGTATAAAGATGTTCACCCAATTATCTATGGATCAAGCGTATTATTTGTTGTATACTTCATCTTAACTGCAAACC
TCATTTAA

Upstream 100 bases:

>100_bases
TTGTCATGTAGATAGAAACCCTTTGTACCTTCAGCAAGTTCAAATGGTTTTTTTTGTTTTTGACATCCTTTCAAACAAAA
AAGAAAAAGGAGAATCATAA

Downstream 100 bases:

>100_bases
TACATAAATTATTTAATTAATTAAACAAAAGAGTTCACTTAGCTGGAAGTGAACTCTTTTTGTATGTTAGTAAGATGTTT
GAATCATCTAAGAATATGAA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNQIKKFFKFEERGASFRAEIIGGIVTFLAMSYILVVNPGIASGLWSGEAGIPYGGVFFATVVGAFIATMVMALLANLPI
GLAPGMGVNAFFVGVIIGQYGYTWQEALALSFIGGLLFLLISLTPLRRTLIQAIPQDLKAAIGVGIGFFIAFVGLRLSGV
FVWNGQLQLGDLTSPSVLLGLFSVVLIFIVHSLKHGISKFSFIISIVVTALVGLLLGQLGVQNMPSFGEFNYDAFADIPN
VAFVGVFEGFKTVFTQPVFTTLFLVFALLFVDIFDTAGTLVAVGKSAGLEDSEGNIPNLDKALLADSIGTLVSSTLGTPE
ITSYVESTTGVEAGAKTGFSSVVVALLFLLSLALFPIFNIFTHSSVTLGALVLVGVLMSQQLKEIDWSNMTSAITAFVVI
VGMIFTSSIADGIAFGFIVYTLIKLVRGEYKDVHPIIYGSSVLFVVYFILTANLI

Sequences:

>Translated_455_residues
MNQIKKFFKFEERGASFRAEIIGGIVTFLAMSYILVVNPGIASGLWSGEAGIPYGGVFFATVVGAFIATMVMALLANLPI
GLAPGMGVNAFFVGVIIGQYGYTWQEALALSFIGGLLFLLISLTPLRRTLIQAIPQDLKAAIGVGIGFFIAFVGLRLSGV
FVWNGQLQLGDLTSPSVLLGLFSVVLIFIVHSLKHGISKFSFIISIVVTALVGLLLGQLGVQNMPSFGEFNYDAFADIPN
VAFVGVFEGFKTVFTQPVFTTLFLVFALLFVDIFDTAGTLVAVGKSAGLEDSEGNIPNLDKALLADSIGTLVSSTLGTPE
ITSYVESTTGVEAGAKTGFSSVVVALLFLLSLALFPIFNIFTHSSVTLGALVLVGVLMSQQLKEIDWSNMTSAITAFVVI
VGMIFTSSIADGIAFGFIVYTLIKLVRGEYKDVHPIIYGSSVLFVVYFILTANLI
>Mature_455_residues
MNQIKKFFKFEERGASFRAEIIGGIVTFLAMSYILVVNPGIASGLWSGEAGIPYGGVFFATVVGAFIATMVMALLANLPI
GLAPGMGVNAFFVGVIIGQYGYTWQEALALSFIGGLLFLLISLTPLRRTLIQAIPQDLKAAIGVGIGFFIAFVGLRLSGV
FVWNGQLQLGDLTSPSVLLGLFSVVLIFIVHSLKHGISKFSFIISIVVTALVGLLLGQLGVQNMPSFGEFNYDAFADIPN
VAFVGVFEGFKTVFTQPVFTTLFLVFALLFVDIFDTAGTLVAVGKSAGLEDSEGNIPNLDKALLADSIGTLVSSTLGTPE
ITSYVESTTGVEAGAKTGFSSVVVALLFLLSLALFPIFNIFTHSSVTLGALVLVGVLMSQQLKEIDWSNMTSAITAFVVI
VGMIFTSSIADGIAFGFIVYTLIKLVRGEYKDVHPIIYGSSVLFVVYFILTANLI

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=453, Percent_Identity=36.2030905077263, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1790150, Length=458, Percent_Identity=36.2445414847162, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1790499, Length=441, Percent_Identity=31.0657596371882, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI48994909, Length=438, Percent_Identity=30.1369863013699, Blast_Score=155, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48413; Mature: 48413

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]