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The map label for this gene is hflX [H]

Identifier: 162448206

GI number: 162448206

Start: 1431225

End: 1432475

Strand: Direct

Name: hflX [H]

Synonym: ACL_1370

Alternate gene names: 162448206

Gene position: 1431225-1432475 (Clockwise)

Preceding gene: 162448205

Following gene: 162448207

Centisome position: 95.61

GC content: 31.1

Gene sequence:

>1251_bases
ATGCAAAAGCTTGATAGAGCTATTTTAGTTGCACTTAATTATCAAGGTAATTATGAATCATGTAAGCTGTCACTTGATGA
ATTAGAAGAGTTAGCAAAAGCTGTTCAAATTAAGACTGTAGATAAAGTTATTCAATCCAATGATAAAATTGAACCTAAAT
TTTTTATTGGTAGTGGAAAAGTTTTAGAAATCAAACAAATGATAGATATCTTAAATGTTGATATGGTTATTTTTGATGAT
ACCTTATCCCCTGCCCAAATCAGAAACTTAGAAGAGGCTTTAGATGTTCAAATATTTGACCGTGCCTTTTTAATTTTACA
GATTTTTGCATTAAGAGCTCAAACCAAGCAGGCTATGCTTGAAGTTGCACTTGCTCAAAAACTTTATATGCTACCACGTT
TAGCTGGTATGGGTAAATCTCTATCTAGACAAGGTGGTGGTTCATTTAACGCTAAAGGGCCTGGTGAAACCAAATTGGAA
ACAGATAGACGTCGATTAAATATGGAAATCACACGTTTAAGAGTATCGCTTGAAGGTATTAAAAAAGAGCGTGGTGAATC
TCGAAAACGTCGCTTTAAAAATAGTATTCCAGTTGTAGCACTTGTTGGTTATACCAATGCCGGTAAGTCTTCTTTAATGA
ATCATTTATCTAATCTATATGGTACAAATAAAACTGAAGTATTTGAAAAGGATATGTTATTTGCTACACTAGACACGAAA
TCTAAACGTATTCAAAAAGACAATCAACCACCTTTTATCTTAATTGATACCGTAGGTTTTATATCTAAACTACCACCAGA
GTTAATTAAATCTTTTGAATCTACTCTAGCAGATATTGCTTCAGCTGATCTTATCTTACATATTGTTGATGGTAAAAACT
ATAGTCCGCTACAAATAAACTTCACTAAACAAGTCATTAAAGATCTTGGTTTAGAAGAAACACCTAGATTACTTGTAGTG
ACTAAGAAAGATTTATTAGTACATCAACCAAATATATTAGAAGATTATTTATTAATCTCTAATAAAACTGGTGAAGGCAT
GAATGACTTATATCAAGCAATTAGTGCACATATCTATAAAGACTCAAGAATATTTAAACTACTACTTCCTTTTGATAAGG
GTTCTATTTATGAACGTCTAAAATCAGATACAACCATTATTGAAACAAACTACACTGCTGATGGTATGTTTGTTAAGGTT
GTACTCACACCTTATCTTTATAATTTATATAAACCTTATATCATGAATTAA

Upstream 100 bases:

>100_bases
GTTTACCCAGTTGTACCACCCAAAGTAGAATATGAATTAACTGAATTAGGTTATAGTTTAAAACTTGTGATAGACGCACT
TAGAAAATGGGGAGAATTAT

Downstream 100 bases:

>100_bases
TTTTTACAAAATTTACACATTCTATACAATTGATTTATTGCAAATTTGATCTTCACATGATATACTTTTTCCATGTTTGA
TAGTTTTGTCGTATAATTGG

Product: HflX subfamily GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MQKLDRAILVALNYQGNYESCKLSLDELEELAKAVQIKTVDKVIQSNDKIEPKFFIGSGKVLEIKQMIDILNVDMVIFDD
TLSPAQIRNLEEALDVQIFDRAFLILQIFALRAQTKQAMLEVALAQKLYMLPRLAGMGKSLSRQGGGSFNAKGPGETKLE
TDRRRLNMEITRLRVSLEGIKKERGESRKRRFKNSIPVVALVGYTNAGKSSLMNHLSNLYGTNKTEVFEKDMLFATLDTK
SKRIQKDNQPPFILIDTVGFISKLPPELIKSFESTLADIASADLILHIVDGKNYSPLQINFTKQVIKDLGLEETPRLLVV
TKKDLLVHQPNILEDYLLISNKTGEGMNDLYQAISAHIYKDSRIFKLLLPFDKGSIYERLKSDTTIIETNYTADGMFVKV
VLTPYLYNLYKPYIMN

Sequences:

>Translated_416_residues
MQKLDRAILVALNYQGNYESCKLSLDELEELAKAVQIKTVDKVIQSNDKIEPKFFIGSGKVLEIKQMIDILNVDMVIFDD
TLSPAQIRNLEEALDVQIFDRAFLILQIFALRAQTKQAMLEVALAQKLYMLPRLAGMGKSLSRQGGGSFNAKGPGETKLE
TDRRRLNMEITRLRVSLEGIKKERGESRKRRFKNSIPVVALVGYTNAGKSSLMNHLSNLYGTNKTEVFEKDMLFATLDTK
SKRIQKDNQPPFILIDTVGFISKLPPELIKSFESTLADIASADLILHIVDGKNYSPLQINFTKQVIKDLGLEETPRLLVV
TKKDLLVHQPNILEDYLLISNKTGEGMNDLYQAISAHIYKDSRIFKLLLPFDKGSIYERLKSDTTIIETNYTADGMFVKV
VLTPYLYNLYKPYIMN
>Mature_416_residues
MQKLDRAILVALNYQGNYESCKLSLDELEELAKAVQIKTVDKVIQSNDKIEPKFFIGSGKVLEIKQMIDILNVDMVIFDD
TLSPAQIRNLEEALDVQIFDRAFLILQIFALRAQTKQAMLEVALAQKLYMLPRLAGMGKSLSRQGGGSFNAKGPGETKLE
TDRRRLNMEITRLRVSLEGIKKERGESRKRRFKNSIPVVALVGYTNAGKSSLMNHLSNLYGTNKTEVFEKDMLFATLDTK
SKRIQKDNQPPFILIDTVGFISKLPPELIKSFESTLADIASADLILHIVDGKNYSPLQINFTKQVIKDLGLEETPRLLVV
TKKDLLVHQPNILEDYLLISNKTGEGMNDLYQAISAHIYKDSRIFKLLLPFDKGSIYERLKSDTTIIETNYTADGMFVKV
VLTPYLYNLYKPYIMN

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=138, Percent_Identity=36.9565217391304, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI310124267, Length=138, Percent_Identity=36.9565217391304, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI310124171, Length=138, Percent_Identity=36.9565217391304, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI310124169, Length=138, Percent_Identity=36.9565217391304, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI310133116, Length=147, Percent_Identity=36.0544217687075, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI310133118, Length=147, Percent_Identity=36.0544217687075, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1790615, Length=364, Percent_Identity=37.0879120879121, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17561038, Length=344, Percent_Identity=29.6511627906977, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24650079, Length=253, Percent_Identity=32.8063241106719, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47168; Mature: 47168

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLDRAILVALNYQGNYESCKLSLDELEELAKAVQIKTVDKVIQSNDKIEPKFFIGSGK
CCCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
VLEIKQMIDILNVDMVIFDDTLSPAQIRNLEEALDVQIFDRAFLILQIFALRAQTKQAML
EEEHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVALAQKLYMLPRLAGMGKSLSRQGGGSFNAKGPGETKLETDRRRLNMEITRLRVSLEGI
HHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHH
KKERGESRKRRFKNSIPVVALVGYTNAGKSSLMNHLSNLYGTNKTEVFEKDMLFATLDTK
HHHCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHEEEEECCC
SKRIQKDNQPPFILIDTVGFISKLPPELIKSFESTLADIASADLILHIVDGKNYSPLQIN
HHHHCCCCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEE
FTKQVIKDLGLEETPRLLVVTKKDLLVHQPNILEDYLLISNKTGEGMNDLYQAISAHIYK
HHHHHHHHCCCCCCCCEEEEEECCCEEECCCHHHHHHEEECCCCCCHHHHHHHHHHHHCC
DSRIFKLLLPFDKGSIYERLKSDTTIIETNYTADGMFVKVVLTPYLYNLYKPYIMN
CCCEEEEEEECCCCHHHHHHCCCCEEEEECCCCCCEEEEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKLDRAILVALNYQGNYESCKLSLDELEELAKAVQIKTVDKVIQSNDKIEPKFFIGSGK
CCCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
VLEIKQMIDILNVDMVIFDDTLSPAQIRNLEEALDVQIFDRAFLILQIFALRAQTKQAML
EEEHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVALAQKLYMLPRLAGMGKSLSRQGGGSFNAKGPGETKLETDRRRLNMEITRLRVSLEGI
HHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHH
KKERGESRKRRFKNSIPVVALVGYTNAGKSSLMNHLSNLYGTNKTEVFEKDMLFATLDTK
HHHCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHEEEEECCC
SKRIQKDNQPPFILIDTVGFISKLPPELIKSFESTLADIASADLILHIVDGKNYSPLQIN
HHHHCCCCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEE
FTKQVIKDLGLEETPRLLVVTKKDLLVHQPNILEDYLLISNKTGEGMNDLYQAISAHIYK
HHHHHHHHCCCCCCCCEEEEEECCCEEECCCHHHHHHEEECCCCCCHHHHHHHHHHHHCC
DSRIFKLLLPFDKGSIYERLKSDTTIIETNYTADGMFVKVVLTPYLYNLYKPYIMN
CCCEEEEEEECCCCHHHHHHCCCCEEEEECCCCCCEEEEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]