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The map label for this gene is nouN

Identifier: 162148799

GI number: 162148799

Start: 3118483

End: 3119910

Strand: Reverse

Name: nouN

Synonym: GDI_3028

Alternate gene names: 162148799

Gene position: 3119910-3118483 (Counterclockwise)

Preceding gene: 162148800

Following gene: 162148798

Centisome position: 79.1

GC content: 64.43

Gene sequence:

>1428_bases
ATGAACTGGACACTTGCACTGCCGGAAATCGTCCTGGCGCTCTGTGGCCTCGCTATCCTCGTCTTCGGCGTGGTGCAGAA
GAAGGAGCAGCCGTTCCTGTCCTGCTCCATGCTGACGATCGGCGCGTTCGTGCTGACCGGTTTCCTGGTCGTGATGTCGC
CGGACGGGGTCGGATACAACCATATCTTCGTCAATGACGATTTCGCCCGCTTCATGAAGATCCTCAGCCTGGCGGGCGGG
GCATTCGCCACCATGCTGACGGTCGGCTACGCGCGGAACATGAAGGTGGAACGGTTCGAATTTCCCGTCCTGCTGCTGTT
CTCGACCCTGGGTGCGATGATGATGGCGTCGTCCGAGAACCTGATGACGCTGTTCATCGGCCTGGAACTGTCGTCGCTTG
CCATCTACATCCTCTGCGCCTTCGCACGGGACGAGGTCAGGGGCGGCGAGGCCGGGCTGAAATATTTCGTCCTGGGCTCG
CTGGCCTCCGGCCTGCTGCTCTACGGCTCGTCCCTGGTCTACGGCTATGCCGGCACGATGGAATATGGCGGCATCCAGAT
GGCGCTCAGCACCAGTTCCACCGCCGTGCCGATGGGCCTGATGTTCGGCATCGTGTTCATGCTGGCCGGGCTGACCTTCA
AGCTGTCGGCGGTGCCGTTCCATATGTGGACACCGGACGTCTACCAGGGCGCGCCGACCTCGGTGACCGCGTACATGGCC
GGCGCGCCGAAATTCGCGGCCTTCGCGCTGCTGCTGCGGGTCATGGCCGGTCCCTTCGGCCATGTCGCGCCGCAATGGCA
GATCCTGGTCGAAGGTGTCTCGATGCTCTCGATGCTGTTCGGTTCGCTGGCGGCCATTCCCCAGACCGACATCAAGCGGC
TGATGGCCTATTCCTCGATCGGCCATATGGGCTACGCCCTGATGGGCCTGTGCGCCGGCACGGCCGAGGGCATGCGCGGC
ACGCTGGTCTATCTGACCACGTACCTGCTGATGAATGTCGGCGCCTTCGCCGTCATCATCGCCATGCGCCGCAAGGGGCG
TGAAGTGACCGGGATCGCCGACCTGGCCGGGCTGGGCAAGACCGATCCGGGCCTGGCCACCGCCATGGCGATCTTCATGT
TCAGCATGGCGGGTGCGCCGCCGCTGGCCGGGTTTTTCGGCAAGATGATGGTGTTCTATGCCGCGATCAACGCCCACCTG
TTCGGCCTGGCGGCCATCGGCGTCGTCAGCAGCGTGATCGGCGGCTACTACTATGTCCGCATCGTCAAGGTGATGTTCTT
TGACGACGCCGCGGCCCCCCTCGATCGCCGGCCGCTGTCGCTGTCCTTCGTCTCGGTGGGCATGGGCATCGCCACCACCG
GCTTCCTGCTGGTGCTGGGACCGGTATCCAGCGCGGCGCAGGCGGCGGCCCAGGCCCTGTTCAGGTGA

Upstream 100 bases:

>100_bases
CGATCGCGGTCTATGCCTTCACGATGCTGATCGGCCTGGTGGTGCTCGTCTCCACCATGCTGGTCTTCCACTGATCTTTC
CGGGAAACGGGTCTGAACCG

Downstream 100 bases:

>100_bases
ACGGCGCGACGCCGGTCGCACCCGTACCGCCGCCGGGGCCGACACCCTGGCGGCTGGAGATTCATGACGAACTGGACTCG
ACGTCCGATACCTGCCTGGC

Product: NADH-quinone oxidoreductase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MNWTLALPEIVLALCGLAILVFGVVQKKEQPFLSCSMLTIGAFVLTGFLVVMSPDGVGYNHIFVNDDFARFMKILSLAGG
AFATMLTVGYARNMKVERFEFPVLLLFSTLGAMMMASSENLMTLFIGLELSSLAIYILCAFARDEVRGGEAGLKYFVLGS
LASGLLLYGSSLVYGYAGTMEYGGIQMALSTSSTAVPMGLMFGIVFMLAGLTFKLSAVPFHMWTPDVYQGAPTSVTAYMA
GAPKFAAFALLLRVMAGPFGHVAPQWQILVEGVSMLSMLFGSLAAIPQTDIKRLMAYSSIGHMGYALMGLCAGTAEGMRG
TLVYLTTYLLMNVGAFAVIIAMRRKGREVTGIADLAGLGKTDPGLATAMAIFMFSMAGAPPLAGFFGKMMVFYAAINAHL
FGLAAIGVVSSVIGGYYYVRIVKVMFFDDAAAPLDRRPLSLSFVSVGMGIATTGFLLVLGPVSSAAQAAAQALFR

Sequences:

>Translated_475_residues
MNWTLALPEIVLALCGLAILVFGVVQKKEQPFLSCSMLTIGAFVLTGFLVVMSPDGVGYNHIFVNDDFARFMKILSLAGG
AFATMLTVGYARNMKVERFEFPVLLLFSTLGAMMMASSENLMTLFIGLELSSLAIYILCAFARDEVRGGEAGLKYFVLGS
LASGLLLYGSSLVYGYAGTMEYGGIQMALSTSSTAVPMGLMFGIVFMLAGLTFKLSAVPFHMWTPDVYQGAPTSVTAYMA
GAPKFAAFALLLRVMAGPFGHVAPQWQILVEGVSMLSMLFGSLAAIPQTDIKRLMAYSSIGHMGYALMGLCAGTAEGMRG
TLVYLTTYLLMNVGAFAVIIAMRRKGREVTGIADLAGLGKTDPGLATAMAIFMFSMAGAPPLAGFFGKMMVFYAAINAHL
FGLAAIGVVSSVIGGYYYVRIVKVMFFDDAAAPLDRRPLSLSFVSVGMGIATTGFLLVLGPVSSAAQAAAQALFR
>Mature_475_residues
MNWTLALPEIVLALCGLAILVFGVVQKKEQPFLSCSMLTIGAFVLTGFLVVMSPDGVGYNHIFVNDDFARFMKILSLAGG
AFATMLTVGYARNMKVERFEFPVLLLFSTLGAMMMASSENLMTLFIGLELSSLAIYILCAFARDEVRGGEAGLKYFVLGS
LASGLLLYGSSLVYGYAGTMEYGGIQMALSTSSTAVPMGLMFGIVFMLAGLTFKLSAVPFHMWTPDVYQGAPTSVTAYMA
GAPKFAAFALLLRVMAGPFGHVAPQWQILVEGVSMLSMLFGSLAAIPQTDIKRLMAYSSIGHMGYALMGLCAGTAEGMRG
TLVYLTTYLLMNVGAFAVIIAMRRKGREVTGIADLAGLGKTDPGLATAMAIFMFSMAGAPPLAGFFGKMMVFYAAINAHL
FGLAAIGVVSSVIGGYYYVRIVKVMFFDDAAAPLDRRPLSLSFVSVGMGIATTGFLLVLGPVSSAAQAAAQALFR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831108, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI145693160, Length=391, Percent_Identity=37.3401534526854, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1788614, Length=321, Percent_Identity=26.791277258567, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788831, Length=313, Percent_Identity=26.1980830670927, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788613, Length=362, Percent_Identity=23.7569060773481, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788827, Length=316, Percent_Identity=27.2151898734177, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367154, Length=333, Percent_Identity=25.5255255255255, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_GLUDA (A9HRS3)

Other databases:

- EMBL:   CP001189
- EMBL:   AM889285
- RefSeq:   YP_001603260.1
- RefSeq:   YP_002277682.1
- GeneID:   5791853
- GeneID:   6976783
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_3340
- HOGENOM:   HBG747830
- OMA:   MDMNTLL
- ProtClustDB:   CLSK958097
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 50384; Mature: 50384

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14da9200)-; HASH(0x17c91388)-; HASH(0x172f2f7c)-; HASH(0x95b09c8)-; HASH(0x956d978)-; HASH(0x1778002c)-; HASH(0x14a0263c)-; HASH(0x13e05344)-; HASH(0x17be851c)-; HASH(0x17c4d984)-; HASH(0x13e04628)-; HASH(0x160207ac)-; HASH(0x1795edd8)-; HASH(0x159d5f40)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWTLALPEIVLALCGLAILVFGVVQKKEQPFLSCSMLTIGAFVLTGFLVVMSPDGVGYN
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCE
HIFVNDDFARFMKILSLAGGAFATMLTVGYARNMKVERFEFPVLLLFSTLGAMMMASSEN
EEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHHHCCCCC
LMTLFIGLELSSLAIYILCAFARDEVRGGEAGLKYFVLGSLASGLLLYGSSLVYGYAGTM
EEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEECCCE
EYGGIQMALSTSSTAVPMGLMFGIVFMLAGLTFKLSAVPFHMWTPDVYQGAPTSVTAYMA
ECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECEEECCCCHHHCCCCCCEEEEEC
GAPKFAAFALLLRVMAGPFGHVAPQWQILVEGVSMLSMLFGSLAAIPQTDIKRLMAYSSI
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GHMGYALMGLCAGTAEGMRGTLVYLTTYLLMNVGAFAVIIAMRRKGREVTGIADLAGLGK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
TDPGLATAMAIFMFSMAGAPPLAGFFGKMMVFYAAINAHLFGLAAIGVVSSVIGGYYYVR
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVKVMFFDDAAAPLDRRPLSLSFVSVGMGIATTGFLLVLGPVSSAAQAAAQALFR
HHHHHHCCCCCCCCCCCCCEEEHHHHCCCHHHHCCEEEECCCCHHHHHHHHHHCH
>Mature Secondary Structure
MNWTLALPEIVLALCGLAILVFGVVQKKEQPFLSCSMLTIGAFVLTGFLVVMSPDGVGYN
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCE
HIFVNDDFARFMKILSLAGGAFATMLTVGYARNMKVERFEFPVLLLFSTLGAMMMASSEN
EEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHHHCCCCC
LMTLFIGLELSSLAIYILCAFARDEVRGGEAGLKYFVLGSLASGLLLYGSSLVYGYAGTM
EEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEECCCE
EYGGIQMALSTSSTAVPMGLMFGIVFMLAGLTFKLSAVPFHMWTPDVYQGAPTSVTAYMA
ECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECEEECCCCHHHCCCCCCEEEEEC
GAPKFAAFALLLRVMAGPFGHVAPQWQILVEGVSMLSMLFGSLAAIPQTDIKRLMAYSSI
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GHMGYALMGLCAGTAEGMRGTLVYLTTYLLMNVGAFAVIIAMRRKGREVTGIADLAGLGK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
TDPGLATAMAIFMFSMAGAPPLAGFFGKMMVFYAAINAHLFGLAAIGVVSSVIGGYYYVR
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVKVMFFDDAAAPLDRRPLSLSFVSVGMGIATTGFLLVLGPVSSAAQAAAQALFR
HHHHHHCCCCCCCCCCCCCEEEHHHHCCCHHHHCCEEEECCCCHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA