Click here to switch to the map view.

The map label for this gene is nouL [H]

Identifier: 162148800

GI number: 162148800

Start: 3119937

End: 3121817

Strand: Reverse

Name: nouL [H]

Synonym: GDI_3029

Alternate gene names: 162148800

Gene position: 3121817-3119937 (Counterclockwise)

Preceding gene: 162148801

Following gene: 162148799

Centisome position: 79.15

GC content: 65.34

Gene sequence:

>1881_bases
GTGGCGGGCCTGTTCGGCCGGCTGCTGGGGGACGGCCTGGCCCAGGCGCTGACCACGGGCCTGATGATCATCGCCGCCCT
GTGCGGAGCCGGCGCGCTGTTCCTGGCGATGCATGCCGGCGGCATGCCCGTCGTGGTGCAACTGGCGGACTGGATCCGTG
CCGGCAGCTTCCACGCCGCCTGGACCCTGCGGCTGGATACGCTGTCGCTGTCGATGGTCGCGATGGTGACCTGTGTCTCG
GCGCTCGTTCACCTCTACAGCGTCGGCTATATGGGGCACGAGACGACGCCGACCTACCGGTTCTTCTCATACCTCTCGCT
CTTCACCTTCGCGATGCTGATGCTGGTCACGTCCAACGACCTGGTCCAGCTCTTCTTCGGGTGGGAAGGCGTGGGCCTGT
GCAGCTACCTGCTGATCGGAACCTGGTACGACCGCCCCAGCGCGAACAGCGCCGCGATCAAGGCGTTCGTGGTCAATCGC
GTGGCCGATCTGTTCTTCATGGTGGGCATCGCCCTGCTGTTCGTGGAATTCGGCTCGGTCACCTACGACAATATCTTCGC
GCTCGTCCCGGCGCATGGCGACGACACGTTCACGCTGTTCGGCACCCATCATATCTATGAAGTCATCTGCATGCTGCTGT
TCATCGGTGCGATGGGCAAGTCGGCGCAGCTGTTCCTGCACACCTGGCTGCCCGACGCGATGGAAGGCCCGACGCCGGTC
TCGGCCCTGATCCATGCCGCGACCATGGTCACGGCGGGCGTGTTCCTGATGGCGCGCATGTCGCCGCTGGTGGAATTCGC
CCCGGGCACCAAGGCCTTCGTCGTGTTCATCGGCGCGACGACGTGCTTCTTCGCCGCCACGGTCGGCCTGGTCCAGCCGG
ACATCAAGCGTACGATCGCCTATTCCACCTGCTCGCAGCTCGGCTACATGTTCGCGGCGGTCGGGGTCGGCGCCTATCAG
GCCTCGGTGTTCCACCTGACGACGCATGCCTTCTTCAAGGCGCTGCTGTTCCTGGGCGCCGGCTCGGTCATCCATGCCGT
GCATGACGAACAGGACATGTTCCGCATGGGCGGCCTGTGGAAGAAGATTCCGCTGACCTACGGCGCGATGTGGGTGGGCA
GCCTGGCGCTGGCGGGCATCTTCCCCTTCGCCGGATACTGGTCGAAGGATGCGATCCTGGAAGCGGCCTGGATGGCGCAT
AGCGGACTGGGCTTCTATGCCTGGAGCCTGGGCTGCATCACGGCATTCATCACCGCGCTGTATAGCTGGCGGCTGATCTT
CCTGGTCTTCCACGGCACGCCGCGCGACGCGCACCTGCATGAAGGCGCGCATGAAAGCCCCGCCTGGATGACCATCCCGC
TGGTGCTGCTGGGCTTGGGGGCGGTCCTCGCCGGCCTGCTGCTGGCGCCGTATTTCGTGGGCTCGGGCCAGGCGGCATTC
TGGAACGGTGCGATCGTGAACGCGCCGGGCAACACCATCATCGCGACGCTGGAACAGACGCCGGAACTGATCGCCCTGGT
GCCGACCTTCGCCGGGATCGCCGGCATCGTGGTGGCCTACCTGTGCTACATGGCCAACCCGGCGATACCGTCCGTCCTGG
CGAACAGCCTGCGGCCGCTTTACCTGTTCCTGCTGAACAAATGGTATTTCGACGAACTGTACGAACACATCTTCGTCCGG
CCGTACCGTGCCCTGGCGCGCCTGCTCTGGAAGGGCGCGGACGAAGGCGTGATCGAAGCCATCCCCCAGGGGCTGGCCCG
CATTACGGCGGGGACCGCCACCCAGGCGGTGCGGACCCAGACCGGGTCGATCGCGGTCTATGCCTTCACGATGCTGATCG
GCCTGGTGGTGCTCGTCTCCACCATGCTGGTCTTCCACTGA

Upstream 100 bases:

>100_bases
GAGGTCGAAGACATCACCATGATGAAGGGTTGAGCGGGTCATGGAAACGGCATCCTACCTTTTCGAGATCGCGGTCCTCG
GCCCCCTGTTCGCTGCCCTC

Downstream 100 bases:

>100_bases
TCTTTCCGGGAAACGGGTCTGAACCGATGAACTGGACACTTGCACTGCCGGAAATCGTCCTGGCGCTCTGTGGCCTCGCT
ATCCTCGTCTTCGGCGTGGT

Product: NADH-quinone oxidoreductase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MAGLFGRLLGDGLAQALTTGLMIIAALCGAGALFLAMHAGGMPVVVQLADWIRAGSFHAAWTLRLDTLSLSMVAMVTCVS
ALVHLYSVGYMGHETTPTYRFFSYLSLFTFAMLMLVTSNDLVQLFFGWEGVGLCSYLLIGTWYDRPSANSAAIKAFVVNR
VADLFFMVGIALLFVEFGSVTYDNIFALVPAHGDDTFTLFGTHHIYEVICMLLFIGAMGKSAQLFLHTWLPDAMEGPTPV
SALIHAATMVTAGVFLMARMSPLVEFAPGTKAFVVFIGATTCFFAATVGLVQPDIKRTIAYSTCSQLGYMFAAVGVGAYQ
ASVFHLTTHAFFKALLFLGAGSVIHAVHDEQDMFRMGGLWKKIPLTYGAMWVGSLALAGIFPFAGYWSKDAILEAAWMAH
SGLGFYAWSLGCITAFITALYSWRLIFLVFHGTPRDAHLHEGAHESPAWMTIPLVLLGLGAVLAGLLLAPYFVGSGQAAF
WNGAIVNAPGNTIIATLEQTPELIALVPTFAGIAGIVVAYLCYMANPAIPSVLANSLRPLYLFLLNKWYFDELYEHIFVR
PYRALARLLWKGADEGVIEAIPQGLARITAGTATQAVRTQTGSIAVYAFTMLIGLVVLVSTMLVFH

Sequences:

>Translated_626_residues
MAGLFGRLLGDGLAQALTTGLMIIAALCGAGALFLAMHAGGMPVVVQLADWIRAGSFHAAWTLRLDTLSLSMVAMVTCVS
ALVHLYSVGYMGHETTPTYRFFSYLSLFTFAMLMLVTSNDLVQLFFGWEGVGLCSYLLIGTWYDRPSANSAAIKAFVVNR
VADLFFMVGIALLFVEFGSVTYDNIFALVPAHGDDTFTLFGTHHIYEVICMLLFIGAMGKSAQLFLHTWLPDAMEGPTPV
SALIHAATMVTAGVFLMARMSPLVEFAPGTKAFVVFIGATTCFFAATVGLVQPDIKRTIAYSTCSQLGYMFAAVGVGAYQ
ASVFHLTTHAFFKALLFLGAGSVIHAVHDEQDMFRMGGLWKKIPLTYGAMWVGSLALAGIFPFAGYWSKDAILEAAWMAH
SGLGFYAWSLGCITAFITALYSWRLIFLVFHGTPRDAHLHEGAHESPAWMTIPLVLLGLGAVLAGLLLAPYFVGSGQAAF
WNGAIVNAPGNTIIATLEQTPELIALVPTFAGIAGIVVAYLCYMANPAIPSVLANSLRPLYLFLLNKWYFDELYEHIFVR
PYRALARLLWKGADEGVIEAIPQGLARITAGTATQAVRTQTGSIAVYAFTMLIGLVVLVSTMLVFH
>Mature_625_residues
AGLFGRLLGDGLAQALTTGLMIIAALCGAGALFLAMHAGGMPVVVQLADWIRAGSFHAAWTLRLDTLSLSMVAMVTCVSA
LVHLYSVGYMGHETTPTYRFFSYLSLFTFAMLMLVTSNDLVQLFFGWEGVGLCSYLLIGTWYDRPSANSAAIKAFVVNRV
ADLFFMVGIALLFVEFGSVTYDNIFALVPAHGDDTFTLFGTHHIYEVICMLLFIGAMGKSAQLFLHTWLPDAMEGPTPVS
ALIHAATMVTAGVFLMARMSPLVEFAPGTKAFVVFIGATTCFFAATVGLVQPDIKRTIAYSTCSQLGYMFAAVGVGAYQA
SVFHLTTHAFFKALLFLGAGSVIHAVHDEQDMFRMGGLWKKIPLTYGAMWVGSLALAGIFPFAGYWSKDAILEAAWMAHS
GLGFYAWSLGCITAFITALYSWRLIFLVFHGTPRDAHLHEGAHESPAWMTIPLVLLGLGAVLAGLLLAPYFVGSGQAAFW
NGAIVNAPGNTIIATLEQTPELIALVPTFAGIAGIVVAYLCYMANPAIPSVLANSLRPLYLFLLNKWYFDELYEHIFVRP
YRALARLLWKGADEGVIEAIPQGLARITAGTATQAVRTQTGSIAVYAFTMLIGLVVLVSTMLVFH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=426, Percent_Identity=39.906103286385, Blast_Score=293, Evalue=3e-79,
Organism=Escherichia coli, GI1788614, Length=573, Percent_Identity=42.5828970331588, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1788829, Length=339, Percent_Identity=32.7433628318584, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1788827, Length=470, Percent_Identity=27.4468085106383, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788831, Length=374, Percent_Identity=30.2139037433155, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788613, Length=322, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI145693160, Length=362, Percent_Identity=23.4806629834254, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI2367154, Length=253, Percent_Identity=27.6679841897233, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 67639; Mature: 67508

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLFGRLLGDGLAQALTTGLMIIAALCGAGALFLAMHAGGMPVVVQLADWIRAGSFHAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEE
WTLRLDTLSLSMVAMVTCVSALVHLYSVGYMGHETTPTYRFFSYLSLFTFAMLMLVTSND
EEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LVQLFFGWEGVGLCSYLLIGTWYDRPSANSAAIKAFVVNRVADLFFMVGIALLFVEFGSV
CEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TYDNIFALVPAHGDDTFTLFGTHHIYEVICMLLFIGAMGKSAQLFLHTWLPDAMEGPTPV
CCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHH
SALIHAATMVTAGVFLMARMSPLVEFAPGTKAFVVFIGATTCFFAATVGLVQPDIKRTIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHH
YSTCSQLGYMFAAVGVGAYQASVFHLTTHAFFKALLFLGAGSVIHAVHDEQDMFRMGGLW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHCCCH
KKIPLTYGAMWVGSLALAGIFPFAGYWSKDAILEAAWMAHSGLGFYAWSLGCITAFITAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YSWRLIFLVFHGTPRDAHLHEGAHESPAWMTIPLVLLGLGAVLAGLLLAPYFVGSGQAAF
HHHHHEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WNGAIVNAPGNTIIATLEQTPELIALVPTFAGIAGIVVAYLCYMANPAIPSVLANSLRPL
ECCEEEECCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YLFLLNKWYFDELYEHIFVRPYRALARLLWKGADEGVIEAIPQGLARITAGTATQAVRTQ
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHC
TGSIAVYAFTMLIGLVVLVSTMLVFH
CCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGLFGRLLGDGLAQALTTGLMIIAALCGAGALFLAMHAGGMPVVVQLADWIRAGSFHAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEE
WTLRLDTLSLSMVAMVTCVSALVHLYSVGYMGHETTPTYRFFSYLSLFTFAMLMLVTSND
EEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LVQLFFGWEGVGLCSYLLIGTWYDRPSANSAAIKAFVVNRVADLFFMVGIALLFVEFGSV
CEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TYDNIFALVPAHGDDTFTLFGTHHIYEVICMLLFIGAMGKSAQLFLHTWLPDAMEGPTPV
CCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHH
SALIHAATMVTAGVFLMARMSPLVEFAPGTKAFVVFIGATTCFFAATVGLVQPDIKRTIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHH
YSTCSQLGYMFAAVGVGAYQASVFHLTTHAFFKALLFLGAGSVIHAVHDEQDMFRMGGLW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHCCCH
KKIPLTYGAMWVGSLALAGIFPFAGYWSKDAILEAAWMAHSGLGFYAWSLGCITAFITAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YSWRLIFLVFHGTPRDAHLHEGAHESPAWMTIPLVLLGLGAVLAGLLLAPYFVGSGQAAF
HHHHHEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WNGAIVNAPGNTIIATLEQTPELIALVPTFAGIAGIVVAYLCYMANPAIPSVLANSLRPL
ECCEEEECCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YLFLLNKWYFDELYEHIFVRPYRALARLLWKGADEGVIEAIPQGLARITAGTATQAVRTQ
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHC
TGSIAVYAFTMLIGLVVLVSTMLVFH
CCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]