Click here to switch to the map view.

The map label for this gene is sucD [H]

Identifier: 162148724

GI number: 162148724

Start: 3040700

End: 3041581

Strand: Direct

Name: sucD [H]

Synonym: GDI_2952

Alternate gene names: 162148724

Gene position: 3040700-3041581 (Clockwise)

Preceding gene: 162148723

Following gene: 162148725

Centisome position: 77.09

GC content: 71.43

Gene sequence:

>882_bases
ATGTCCATCCTGGTCCATCGCGGCACCCGCGTCATCACCCAGGGCTTCACCGGCGCCCAGGGCACCTTCCATTCCGAACA
GGCGCTGGCCTACGGCACCCGGCTGGTCGGCGGGGTGACCCCGGGCCGGGGCGGCGCGGTCCATCTGGGCCTGCCGGTCT
TCGACACCGTGTCGCAGGCCCGCGAGGCAACGGGCGCGGACGCCACCGTGCTGTACGTGCCGCCCGACGGCGCCGCCGAT
GCCATCCTGGAGGCCATCGCGGCGGGCATGCCCCTGATCGTGTGCATCACCGAAGGGATTCCGGTCCTGGACATGGTGCG
CGTCCACCAGGTGCTGGCCCGGTCGGACAGCGTACTGATCGGGCCGAACTGCCCGGGCGTCATCACCCCCGGCGAATGCA
AGATCGGCATCATGCCCGGGGCGATCCATCGGCCCGGGCGCGTGGGCATCGTCTCGCGCTCCGGCACGCTGACATACGAG
GCCGTGGCGCAGACGACGGCGGCGGGGCTGGGGCAGAGCACCTGTGTCGGCATCGGCGGCGACCCGGTCAAGGGGCTGGA
CTTCACCGACGTGCTGAAACGCTTCATCGCGGACCCGGACACGGATTCGATCATCATGATCGGCGAGATCGGCGGCACGT
CGGAGATCGAGGCGGCGGCGCTGATCCGCGACAGCGGCACGAAGAAGCCGGTGGTGGGCTTCATCGCCGGTGCCACCGCT
CCGCCGGGGCGCCGCATGGGCCATGCCGGCGCCGTCATCACCGGCGGGCACGAAACGGCGGGGGCCAAGATCGACGCCCT
GCGCGCGGCGGGAATCCATGTCTCGATCAGCCCGGCGCTGCTGGGCCATACGCTGCTGGAGGTCATGGCGGGCCGCGCCT
GA

Upstream 100 bases:

>100_bases
CATCGGGGCTGAGGATCATCCCGGCCGACGACCTGGCCGACGCGGCCACCAAGATCGTCGCCGCCGTGCGCGAAACCGCT
TTCGCCGGGGGGGCCGCCTG

Downstream 100 bases:

>100_bases
CCCGCCCGCCGCACAAGGCGTGCCCGTCCCGTTGCGCGGGCCGGGCACGCCTTGGGTGACACCGCCCCCCCTTCTGTGGC
AGAGCGTGTTCCTTATCGCC

Product: succinyl-CoA ligase [GDP-forming] alpha-chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILVHRGTRVITQGFTGAQGTFHSEQALAYGTRLVGGVTPGRGGAVHLGLPVFDTVSQAREATGADATVLYVPPDGAAD
AILEAIAAGMPLIVCITEGIPVLDMVRVHQVLARSDSVLIGPNCPGVITPGECKIGIMPGAIHRPGRVGIVSRSGTLTYE
AVAQTTAAGLGQSTCVGIGGDPVKGLDFTDVLKRFIADPDTDSIIMIGEIGGTSEIEAAALIRDSGTKKPVVGFIAGATA
PPGRRMGHAGAVITGGHETAGAKIDALRAAGIHVSISPALLGHTLLEVMAGRA

Sequences:

>Translated_293_residues
MSILVHRGTRVITQGFTGAQGTFHSEQALAYGTRLVGGVTPGRGGAVHLGLPVFDTVSQAREATGADATVLYVPPDGAAD
AILEAIAAGMPLIVCITEGIPVLDMVRVHQVLARSDSVLIGPNCPGVITPGECKIGIMPGAIHRPGRVGIVSRSGTLTYE
AVAQTTAAGLGQSTCVGIGGDPVKGLDFTDVLKRFIADPDTDSIIMIGEIGGTSEIEAAALIRDSGTKKPVVGFIAGATA
PPGRRMGHAGAVITGGHETAGAKIDALRAAGIHVSISPALLGHTLLEVMAGRA
>Mature_292_residues
SILVHRGTRVITQGFTGAQGTFHSEQALAYGTRLVGGVTPGRGGAVHLGLPVFDTVSQAREATGADATVLYVPPDGAADA
ILEAIAAGMPLIVCITEGIPVLDMVRVHQVLARSDSVLIGPNCPGVITPGECKIGIMPGAIHRPGRVGIVSRSGTLTYEA
VAQTTAAGLGQSTCVGIGGDPVKGLDFTDVLKRFIADPDTDSIIMIGEIGGTSEIEAAALIRDSGTKKPVVGFIAGATAP
PGRRMGHAGAVITGGHETAGAKIDALRAAGIHVSISPALLGHTLLEVMAGRA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=63.9455782312925, Blast_Score=325, Evalue=3e-89,
Organism=Homo sapiens, GI38569423, Length=254, Percent_Identity=32.2834645669291, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38569421, Length=254, Percent_Identity=32.2834645669291, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=64.7058823529412, Blast_Score=365, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17550194, Length=295, Percent_Identity=58.3050847457627, Blast_Score=332, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17553126, Length=294, Percent_Identity=60.2040816326531, Blast_Score=328, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17557344, Length=257, Percent_Identity=30.3501945525292, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551266, Length=257, Percent_Identity=29.5719844357977, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324716, Length=297, Percent_Identity=49.8316498316498, Blast_Score=275, Evalue=5e-75,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=56.8493150684932, Blast_Score=337, Evalue=5e-93,
Organism=Drosophila melanogaster, GI28574296, Length=285, Percent_Identity=62.8070175438596, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI281363477, Length=253, Percent_Identity=33.201581027668, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281363475, Length=253, Percent_Identity=33.201581027668, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281363473, Length=253, Percent_Identity=33.201581027668, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29612; Mature: 29480

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVHRGTRVITQGFTGAQGTFHSEQALAYGTRLVGGVTPGRGGAVHLGLPVFDTVSQA
CEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHH
REATGADATVLYVPPDGAADAILEAIAAGMPLIVCITEGIPVLDMVRVHQVLARSDSVLI
HHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEE
GPNCPGVITPGECKIGIMPGAIHRPGRVGIVSRSGTLTYEAVAQTTAAGLGQSTCVGIGG
CCCCCCEECCCCEEEEECCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVKGLDFTDVLKRFIADPDTDSIIMIGEIGGTSEIEAAALIRDSGTKKPVVGFIAGATA
CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHEEEEECCCCCCCEEEEEECCCC
PPGRRMGHAGAVITGGHETAGAKIDALRAAGIHVSISPALLGHTLLEVMAGRA
CCCCCCCCCCEEEECCCCCCCCEEEEEEECCEEEEECHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SILVHRGTRVITQGFTGAQGTFHSEQALAYGTRLVGGVTPGRGGAVHLGLPVFDTVSQA
EEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHH
REATGADATVLYVPPDGAADAILEAIAAGMPLIVCITEGIPVLDMVRVHQVLARSDSVLI
HHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEE
GPNCPGVITPGECKIGIMPGAIHRPGRVGIVSRSGTLTYEAVAQTTAAGLGQSTCVGIGG
CCCCCCEECCCCEEEEECCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVKGLDFTDVLKRFIADPDTDSIIMIGEIGGTSEIEAAALIRDSGTKKPVVGFIAGATA
CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHEEEEECCCCCCCEEEEEECCCC
PPGRRMGHAGAVITGGHETAGAKIDALRAAGIHVSISPALLGHTLLEVMAGRA
CCCCCCCCCCEEEECCCCCCCCEEEEEEECCEEEEECHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]