Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 162148723

GI number: 162148723

Start: 3039486

End: 3040700

Strand: Direct

Name: sucC [H]

Synonym: GDI_2951

Alternate gene names: 162148723

Gene position: 3039486-3040700 (Clockwise)

Preceding gene: 162148711

Following gene: 162148724

Centisome position: 77.06

GC content: 69.96

Gene sequence:

>1215_bases
ATGAACATACATGAATATCAGGCAAAGGCCCTGTTGAAGGGCTTCGGCATGCCGGTTCCCGATGGGCGCGTCGTCCGTTC
CCCGGACGAAGCCCTGCTGGCCGCCCGCGCGATGGGCGCCCCGCTGGTGGTGGTCAAGGCGCAGATCCATGCCGGCGGCC
GCGGCGCGGGTCATTTCGCCCATGATCCCGGCGGCAAGGGCGGCGTACGCCTGGCCCGCACGCCCGAGGATGCCGAGCAG
GCCGCCATCGCGATGCTGGACCAGACCCTGGTCACGCGCCAGACCGGCTCTGCCGGCCGCGTGGTCCGCCGCCTGTATAT
CGAGGCCGGATGCGATATCGGGCGCGAGCTGTACCTGTCGCTGCTGGTGGATCGCGGCACTGGGCGCATCGTCATCGTGG
CGTCGCAGGACGGCGGCATGGCGATCGAGGACGTCGCCGCCGCCACGCCCGAGCGTATCCTGAAGGAACCGATCGACCCG
GCCACCGGCCTGTCCGACTACCAGGCGCGCACGCTGGCGGCGCGGCTGGACCTGCATGGACGGTCGATCCGCGCCTTCAC
CACCGTGCTGCGCGCGGCCTATGACGCGTTCGTGGCGCTGGACGCCGCGATCGTCGAGATCAATCCGCTGGTCGTCACCC
GGTCGGGCGACCTTCTGGCGCTGGACGCCAAGATGAGCTTCGACGACAACGCGCTGTTCCGCCATCCGGAACTGGAAGAA
CTGCGCGACGAGAACGAGGAAGACCCCCGCGAGCGCGAGGCCGCGCGCCACGGCCTGGCCTATGTCGGGCTGGACGGGAC
CATCGGCTGCATGGTCAACGGCGCCGGGCTGGCGATGGCGACCATGGACATCATCAAGATGGAGGGCGAGGAACCGGCCA
ACTTCCTGGACGTGGGCGGCGGCGCCACGCGCGAACGGGTGGCGGCGGCGTTCCGCATCCTGCTGTCCGACCGCAAGGTG
CGCGGCATCCTGGTGAACATCTTCGGCGGCATCATGCGCTGCGACATCATCGCGGACGCCATCGTCGCCGCGTCGCGCGA
AACGGGGCTGCACGTGCCGCTGGTGGTGCGGCTGGCCGGCACCAACGTCGAACAGGGGCACCAGATCCTGTCGGCATCGG
GGCTGAGGATCATCCCGGCCGACGACCTGGCCGACGCGGCCACCAAGATCGTCGCCGCCGTGCGCGAAACCGCTTTCGCC
GGGGGGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCAGAGCTGATCGGGACCATGCCCACCCCAGCATGCCACCCGGTTCGCCCCACCCCGGCTTACCCGGGCGCGCAACGATA
ACAAACGCGGATCAAACCGT

Downstream 100 bases:

>100_bases
TGTCCATCCTGGTCCATCGCGGCACCCGCGTCATCACCCAGGGCTTCACCGGCGCCCAGGGCACCTTCCATTCCGAACAG
GCGCTGGCCTACGGCACCCG

Product: succinyl-CoA synthetase beta chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNIHEYQAKALLKGFGMPVPDGRVVRSPDEALLAARAMGAPLVVVKAQIHAGGRGAGHFAHDPGGKGGVRLARTPEDAEQ
AAIAMLDQTLVTRQTGSAGRVVRRLYIEAGCDIGRELYLSLLVDRGTGRIVIVASQDGGMAIEDVAAATPERILKEPIDP
ATGLSDYQARTLAARLDLHGRSIRAFTTVLRAAYDAFVALDAAIVEINPLVVTRSGDLLALDAKMSFDDNALFRHPELEE
LRDENEEDPREREAARHGLAYVGLDGTIGCMVNGAGLAMATMDIIKMEGEEPANFLDVGGGATRERVAAAFRILLSDRKV
RGILVNIFGGIMRCDIIADAIVAASRETGLHVPLVVRLAGTNVEQGHQILSASGLRIIPADDLADAATKIVAAVRETAFA
GGAA

Sequences:

>Translated_404_residues
MNIHEYQAKALLKGFGMPVPDGRVVRSPDEALLAARAMGAPLVVVKAQIHAGGRGAGHFAHDPGGKGGVRLARTPEDAEQ
AAIAMLDQTLVTRQTGSAGRVVRRLYIEAGCDIGRELYLSLLVDRGTGRIVIVASQDGGMAIEDVAAATPERILKEPIDP
ATGLSDYQARTLAARLDLHGRSIRAFTTVLRAAYDAFVALDAAIVEINPLVVTRSGDLLALDAKMSFDDNALFRHPELEE
LRDENEEDPREREAARHGLAYVGLDGTIGCMVNGAGLAMATMDIIKMEGEEPANFLDVGGGATRERVAAAFRILLSDRKV
RGILVNIFGGIMRCDIIADAIVAASRETGLHVPLVVRLAGTNVEQGHQILSASGLRIIPADDLADAATKIVAAVRETAFA
GGAA
>Mature_404_residues
MNIHEYQAKALLKGFGMPVPDGRVVRSPDEALLAARAMGAPLVVVKAQIHAGGRGAGHFAHDPGGKGGVRLARTPEDAEQ
AAIAMLDQTLVTRQTGSAGRVVRRLYIEAGCDIGRELYLSLLVDRGTGRIVIVASQDGGMAIEDVAAATPERILKEPIDP
ATGLSDYQARTLAARLDLHGRSIRAFTTVLRAAYDAFVALDAAIVEINPLVVTRSGDLLALDAKMSFDDNALFRHPELEE
LRDENEEDPREREAARHGLAYVGLDGTIGCMVNGAGLAMATMDIIKMEGEEPANFLDVGGGATRERVAAAFRILLSDRKV
RGILVNIFGGIMRCDIIADAIVAASRETGLHVPLVVRLAGTNVEQGHQILSASGLRIIPADDLADAATKIVAAVRETAFA
GGAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=45.2685421994885, Blast_Score=354, Evalue=8e-98,
Organism=Homo sapiens, GI157779135, Length=385, Percent_Identity=46.7532467532467, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=46.3013698630137, Blast_Score=312, Evalue=4e-85,
Organism=Escherichia coli, GI1786948, Length=395, Percent_Identity=52.6582278481013, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=46.7005076142132, Blast_Score=347, Evalue=5e-96,
Organism=Caenorhabditis elegans, GI17567829, Length=396, Percent_Identity=44.1919191919192, Blast_Score=329, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=44.9238578680203, Blast_Score=338, Evalue=1e-93,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=49.4845360824742, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=49.4845360824742, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI161078106, Length=387, Percent_Identity=49.0956072351421, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24645208, Length=387, Percent_Identity=49.0956072351421, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=46.4646464646465, Blast_Score=341, Evalue=4e-94,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42729; Mature: 42729

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLKGFGMPVPDGRVVRSPDEALLAARAMGAPLVVVKAQIHAGGRGAGHFA
CCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC
HDPGGKGGVRLARTPEDAEQAAIAMLDQTLVTRQTGSAGRVVRRLYIEAGCDIGRELYLS
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LLVDRGTGRIVIVASQDGGMAIEDVAAATPERILKEPIDPATGLSDYQARTLAARLDLHG
HHEECCCCEEEEEEECCCCCCHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
RSIRAFTTVLRAAYDAFVALDAAIVEINPLVVTRSGDLLALDAKMSFDDNALFRHPELEE
CHHHHHHHHHHHHHHHHHHHHEEEEEECEEEEECCCCEEEEEEECCCCCCCEECCCCHHH
LRDENEEDPREREAARHGLAYVGLDGTIGCMVNGAGLAMATMDIIKMEGEEPANFLDVGG
HHCCCCCCHHHHHHHHCCCEEEECCCEEEEEEECCCHHHHHHHHHEECCCCCCCEEECCC
GATRERVAAAFRILLSDRKVRGILVNIFGGIMRCDIIADAIVAASRETGLHVPLVVRLAG
CCHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
TNVEQGHQILSASGLRIIPADDLADAATKIVAAVRETAFAGGAA
CCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNIHEYQAKALLKGFGMPVPDGRVVRSPDEALLAARAMGAPLVVVKAQIHAGGRGAGHFA
CCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC
HDPGGKGGVRLARTPEDAEQAAIAMLDQTLVTRQTGSAGRVVRRLYIEAGCDIGRELYLS
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LLVDRGTGRIVIVASQDGGMAIEDVAAATPERILKEPIDPATGLSDYQARTLAARLDLHG
HHEECCCCEEEEEEECCCCCCHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
RSIRAFTTVLRAAYDAFVALDAAIVEINPLVVTRSGDLLALDAKMSFDDNALFRHPELEE
CHHHHHHHHHHHHHHHHHHHHEEEEEECEEEEECCCCEEEEEEECCCCCCCEECCCCHHH
LRDENEEDPREREAARHGLAYVGLDGTIGCMVNGAGLAMATMDIIKMEGEEPANFLDVGG
HHCCCCCCHHHHHHHHCCCEEEECCCEEEEEEECCCHHHHHHHHHEECCCCCCCEEECCC
GATRERVAAAFRILLSDRKVRGILVNIFGGIMRCDIIADAIVAASRETGLHVPLVVRLAG
CCHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
TNVEQGHQILSASGLRIIPADDLADAATKIVAAVRETAFAGGAA
CCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA