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The map label for this gene is ycgM [C]

Identifier: 162148447

GI number: 162148447

Start: 2759013

End: 2759858

Strand: Reverse

Name: ycgM [C]

Synonym: GDI_2666

Alternate gene names: 162148447

Gene position: 2759858-2759013 (Counterclockwise)

Preceding gene: 162148448

Following gene: 162148446

Centisome position: 69.97

GC content: 65.37

Gene sequence:

>846_bases
ATGAAGCTTTTGAGATTTGGCGAGAAGGGGGCGGAGCGTCCCGGCCTGCTTGACGAAGACGGGCGGGTGCGTGATCTGTC
GGCGCACGTGCCCGACATCGCCGGGCCGGCGCTGTTGCCGGATACCCTGGCGCGTCTGGCCCGGCTCGTGCCCGGCCACC
TGCCGCTGGCGCCCGTGGATGCGCGTATCGGTCCGTGTGTCGGATCGGTCGGAAAATTCATCTGCATCGGCCTGAACTAT
AGGGATCACGCGGCCGAAACCGACAGCCCCATTCCGGAAGAGCCCGTTATCTTCAATAAATGGACCAGCGCCATCGCCGG
GCCGTACGACGATCTTTGCATTCCCCCCGGCTCGACCAAAACAGACTGGGAGGTCGAGCTGGGGGTCGTGATCGGCAAGG
GCGGACGCGCCATCGCGGAGCGTGAGGCCCGCGCGCATATCGCCGGCTATTGCGTGGTCAACGATCTCTCGGAACGCGAA
TGGCAGCTCGAACGGGGCGGAACGTGGGACAAGGGCAAGGGCTATGACGGTTTCGGGCCGATCGGCCCCTGGCTGGTCAC
GACGGACGACATCGAAGACCCGCAAACCCTGCCGATGTGGCTGGAGGTCGATGGCCACCGCTACCAGAACGGCAACACGC
GGACCATGATCTTCGGCGTGGACACGATCGTGTCCTATTGCAGCCGGTTCATGAGCCTGCAGCCCGGCGACATCATCTCG
ACAGGAACACCCCCGGGCGTCGGGCTCGGCCAGCGGCCGCCGGTCTATCTCCGGCCGGGACAGACCGTGCGCCTGGGCAT
CGAGGGACTTGGGATCCAGCAGCAATATGTCAGGGGGGCGGCATGA

Upstream 100 bases:

>100_bases
CGCCGCCGCGTTCGTGACCGGCAGCACGCTGGTCATCGATGGCGGATTCATCAACTGACACCCGGAAGACGCAAGAACAA
CAACAAGGCAGGCGTCCATC

Downstream 100 bases:

>100_bases
CCCGGATCACCGGCCTGCGCGTGTTCGATATCCGCTTTCCGACATCCGCCCGGCTCGACGGGTCGGACGCCATGAATCCG
GACCCGGACTATTCCGCCGC

Product: fumarylacetoacetate (FAA) hydrolase family protein

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKLLRFGEKGAERPGLLDEDGRVRDLSAHVPDIAGPALLPDTLARLARLVPGHLPLAPVDARIGPCVGSVGKFICIGLNY
RDHAAETDSPIPEEPVIFNKWTSAIAGPYDDLCIPPGSTKTDWEVELGVVIGKGGRAIAEREARAHIAGYCVVNDLSERE
WQLERGGTWDKGKGYDGFGPIGPWLVTTDDIEDPQTLPMWLEVDGHRYQNGNTRTMIFGVDTIVSYCSRFMSLQPGDIIS
TGTPPGVGLGQRPPVYLRPGQTVRLGIEGLGIQQQYVRGAA

Sequences:

>Translated_281_residues
MKLLRFGEKGAERPGLLDEDGRVRDLSAHVPDIAGPALLPDTLARLARLVPGHLPLAPVDARIGPCVGSVGKFICIGLNY
RDHAAETDSPIPEEPVIFNKWTSAIAGPYDDLCIPPGSTKTDWEVELGVVIGKGGRAIAEREARAHIAGYCVVNDLSERE
WQLERGGTWDKGKGYDGFGPIGPWLVTTDDIEDPQTLPMWLEVDGHRYQNGNTRTMIFGVDTIVSYCSRFMSLQPGDIIS
TGTPPGVGLGQRPPVYLRPGQTVRLGIEGLGIQQQYVRGAA
>Mature_281_residues
MKLLRFGEKGAERPGLLDEDGRVRDLSAHVPDIAGPALLPDTLARLARLVPGHLPLAPVDARIGPCVGSVGKFICIGLNY
RDHAAETDSPIPEEPVIFNKWTSAIAGPYDDLCIPPGSTKTDWEVELGVVIGKGGRAIAEREARAHIAGYCVVNDLSERE
WQLERGGTWDKGKGYDGFGPIGPWLVTTDDIEDPQTLPMWLEVDGHRYQNGNTRTMIFGVDTIVSYCSRFMSLQPGDIIS
TGTPPGVGLGQRPPVYLRPGQTVRLGIEGLGIQQQYVRGAA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=233, Percent_Identity=44.6351931330472, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI40786394, Length=233, Percent_Identity=43.7768240343348, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI66348062, Length=202, Percent_Identity=37.1287128712871, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI215422413, Length=202, Percent_Identity=37.1287128712871, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=37.3134328358209, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=37.9120879120879, Blast_Score=127, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=36.8715083798883, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=228, Percent_Identity=29.8245614035088, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28572127, Length=285, Percent_Identity=39.2982456140351, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24663695, Length=275, Percent_Identity=32, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571789, Length=179, Percent_Identity=38.5474860335196, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30432; Mature: 30432

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRFGEKGAERPGLLDEDGRVRDLSAHVPDIAGPALLPDTLARLARLVPGHLPLAPVD
CCCCCCCCCCCCCCCCCCCCCCEEEHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
ARIGPCVGSVGKFICIGLNYRDHAAETDSPIPEEPVIFNKWTSAIAGPYDDLCIPPGSTK
CCHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCCEEEECHHHHHCCCCCCEEECCCCCC
TDWEVELGVVIGKGGRAIAEREARAHIAGYCVVNDLSEREWQLERGGTWDKGKGYDGFGP
CCEEEEEEEEECCCCCHHHHHHHHHEEEEEEEECCCCCHHEEHHCCCCCCCCCCCCCCCC
IGPWLVTTDDIEDPQTLPMWLEVDGHRYQNGNTRTMIFGVDTIVSYCSRFMSLQPGDIIS
CCCEEEEECCCCCCCCCEEEEEECCEEECCCCEEEEEEEHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGLGQRPPVYLRPGQTVRLGIEGLGIQQQYVRGAA
CCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHCCCC
>Mature Secondary Structure
MKLLRFGEKGAERPGLLDEDGRVRDLSAHVPDIAGPALLPDTLARLARLVPGHLPLAPVD
CCCCCCCCCCCCCCCCCCCCCCEEEHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
ARIGPCVGSVGKFICIGLNYRDHAAETDSPIPEEPVIFNKWTSAIAGPYDDLCIPPGSTK
CCHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCCEEEECHHHHHCCCCCCEEECCCCCC
TDWEVELGVVIGKGGRAIAEREARAHIAGYCVVNDLSEREWQLERGGTWDKGKGYDGFGP
CCEEEEEEEEECCCCCHHHHHHHHHEEEEEEEECCCCCHHEEHHCCCCCCCCCCCCCCCC
IGPWLVTTDDIEDPQTLPMWLEVDGHRYQNGNTRTMIFGVDTIVSYCSRFMSLQPGDIIS
CCCEEEEECCCCCCCCCEEEEEECCEEECCCCEEEEEEEHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGLGQRPPVYLRPGQTVRLGIEGLGIQQQYVRGAA
CCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA