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The map label for this gene is moaC [H]

Identifier: 162147722

GI number: 162147722

Start: 1972914

End: 1973429

Strand: Direct

Name: moaC [H]

Synonym: GDI_1938

Alternate gene names: 162147722

Gene position: 1972914-1973429 (Clockwise)

Preceding gene: 162147721

Following gene: 162147723

Centisome position: 50.02

GC content: 67.83

Gene sequence:

>516_bases
ATGGCGACTGCCGGCGGATTGTCTCACCTGGACGCCAACGGCCATGCCGTCATGGTCGATGTGTCCACCAAGCCGGCCAC
GGCGCGGCAGGCCGTCGCCCGCGGGCGGGTGTCGATGCGCGAGGAGACGTTGGACCTGATCCTGTCGGGCACCATCAAGA
AGGGTGACGTGCTGGCGGTATCGCGGATCGCGGGAATCATGGCGGCCAAGAAGACCGCCGACCTGATCCCGCTCTGCCAC
CCGCTTCCATTGTCCTCGGTCCGGGTGGAACTGACGGCGTCCCATGACCGGACCGGGGTGGAGATCGAGGCCTGCGTCGG
CACCACCGGTCAGACCGGGGTGGAGATGGAGGCCCTGACGGCGGTCAGCGTGGCGGCGCTGACGCTGTACGATATGTGCA
AGGCGGTCGATCGCGGCATGACGATCGAGGCGGTGTACCTGGCGCGCAAGACGGGCGGGCAATCCGGCTCGTACGAACGC
CCCGAAGCGGGAGCGGCACCGACACCCATGGCATAA

Upstream 100 bases:

>100_bases
TGAGCGAGATCGGCGCCAGCGGCTTCCTGGTCGGCGAGAGCCTGCTGCGCCACGATGTCCCCGGCGACGCGGCCCGCGTG
CTGCTGGGCACGGTCTGAAC

Downstream 100 bases:

>100_bases
CCATCCGAACGGCAGGCGCACGGCCTGGCCATGACAAGGGCGATCAGACGTCCCGGGTGGGATCTGGCTTGCGATCAAAG
ATGTTATAACAAGAACAAGG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MATAGGLSHLDANGHAVMVDVSTKPATARQAVARGRVSMREETLDLILSGTIKKGDVLAVSRIAGIMAAKKTADLIPLCH
PLPLSSVRVELTASHDRTGVEIEACVGTTGQTGVEMEALTAVSVAALTLYDMCKAVDRGMTIEAVYLARKTGGQSGSYER
PEAGAAPTPMA

Sequences:

>Translated_171_residues
MATAGGLSHLDANGHAVMVDVSTKPATARQAVARGRVSMREETLDLILSGTIKKGDVLAVSRIAGIMAAKKTADLIPLCH
PLPLSSVRVELTASHDRTGVEIEACVGTTGQTGVEMEALTAVSVAALTLYDMCKAVDRGMTIEAVYLARKTGGQSGSYER
PEAGAAPTPMA
>Mature_170_residues
ATAGGLSHLDANGHAVMVDVSTKPATARQAVARGRVSMREETLDLILSGTIKKGDVLAVSRIAGIMAAKKTADLIPLCHP
LPLSSVRVELTASHDRTGVEIEACVGTTGQTGVEMEALTAVSVAALTLYDMCKAVDRGMTIEAVYLARKTGGQSGSYERP
EAGAAPTPMA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=58.1699346405229, Blast_Score=168, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=152, Percent_Identity=48.0263157894737, Blast_Score=139, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28574490, Length=159, Percent_Identity=53.4591194968553, Blast_Score=153, Evalue=6e-38,
Organism=Drosophila melanogaster, GI28574492, Length=148, Percent_Identity=54.0540540540541, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17677; Mature: 17545

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAGGLSHLDANGHAVMVDVSTKPATARQAVARGRVSMREETLDLILSGTIKKGDVLAV
CCCCCCCCEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHH
SRIAGIMAAKKTADLIPLCHPLPLSSVRVELTASHDRTGVEIEACVGTTGQTGVEMEALT
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHH
AVSVAALTLYDMCKAVDRGMTIEAVYLARKTGGQSGSYERPEAGAAPTPMA
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATAGGLSHLDANGHAVMVDVSTKPATARQAVARGRVSMREETLDLILSGTIKKGDVLAV
CCCCCCCEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHH
SRIAGIMAAKKTADLIPLCHPLPLSSVRVELTASHDRTGVEIEACVGTTGQTGVEMEALT
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHH
AVSVAALTLYDMCKAVDRGMTIEAVYLARKTGGQSGSYERPEAGAAPTPMA
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA