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The map label for this gene is kdsA [H]

Identifier: 162147713

GI number: 162147713

Start: 1962730

End: 1963566

Strand: Reverse

Name: kdsA [H]

Synonym: GDI_1929

Alternate gene names: 162147713

Gene position: 1963566-1962730 (Counterclockwise)

Preceding gene: 162147714

Following gene: 162147711

Centisome position: 49.78

GC content: 68.82

Gene sequence:

>837_bases
ATGACCCATCCGAAATCCGTCTCGCTCGGCAGCCTGACCGTCGGCAACGATCGTCCCTTCGTCCTGATCGCCGGGCCGTG
CCAGATCGAATCCGAAGCCCATGCGATGGAAACGGCCGACGCGCTGCACGGCATCGCACGGGAAACCGGGGTCGGCCTGA
TCTATAAAAGCTCGTTCGACAAGGCGAACCGCACCAGCCTGGGCGCCGCGCGTGGCGTGGGCATGGCGGCGGGGCTGGAA
ATCCTGGCACGGGTGCGCGAGCGATTCGGCGTGCCGGTGCTGACGGACGTGCATGCGGCGGACCAGTGCGCCCCCACCGC
CGCCGCCGTGGACGTGCTGCAGATCCCGGCCTTCCTGTGCCGCCAGACCGACCTGCTGCTGGCGGCCGGGGAAACCGGGG
CCGCGATCAACGTCAAGAAGGGGCAGTTCCTGGCGCCGTGGGACATGACGAATGTCGCGGCCAAGATCGCCTCGACCGGC
AACGAGCGCATCATGCTGTGCGAGCGCGGGACCAGCTTCGGCTACAACACGCTGGTCAATGACATGCGCGGCCTGCCGAT
CATGGCGGCGACCGGCTATCCGGTCGTGTACGACGCCACCCATTCGGTCCAGCAGCCGGGCGGCCTGGGCGGATCGTCGG
GCGGCCAGCGGGAATTCGCCCCCATCCTGGCACGGGGGGCGCTGGCGATCGGCGTCGCGGCGGTCTTCATCGAAACGCAC
CAGGACCCGGACAGCGCGCCCAGCGACGGACCGAACATGATCCCGATCCGGGACATGAAGGCCCTGGTCCAGCGCCTGGC
CCAATATGACCGGCTGACCAAGGCCGGCACCCCGTAG

Upstream 100 bases:

>100_bases
TCGCGGTGCAGTACCATCCCGAACTGCTGTCCAAGCCGTTCGATCCGCATCCGCTTTTCTCGGGCTTCGTCGGCGCGGCC
GTGAAGAAGATGCGGCTGGT

Downstream 100 bases:

>100_bases
GCCCCCCCCTGGCCCGCGTCATATCGCGCGGGCCAGCAGCGCCACCGCCAGACAGGTCATGATGACGGCGGTCATGCACA
GCCGCAGCGCCAGATAGCCG

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTHPKSVSLGSLTVGNDRPFVLIAGPCQIESEAHAMETADALHGIARETGVGLIYKSSFDKANRTSLGAARGVGMAAGLE
ILARVRERFGVPVLTDVHAADQCAPTAAAVDVLQIPAFLCRQTDLLLAAGETGAAINVKKGQFLAPWDMTNVAAKIASTG
NERIMLCERGTSFGYNTLVNDMRGLPIMAATGYPVVYDATHSVQQPGGLGGSSGGQREFAPILARGALAIGVAAVFIETH
QDPDSAPSDGPNMIPIRDMKALVQRLAQYDRLTKAGTP

Sequences:

>Translated_278_residues
MTHPKSVSLGSLTVGNDRPFVLIAGPCQIESEAHAMETADALHGIARETGVGLIYKSSFDKANRTSLGAARGVGMAAGLE
ILARVRERFGVPVLTDVHAADQCAPTAAAVDVLQIPAFLCRQTDLLLAAGETGAAINVKKGQFLAPWDMTNVAAKIASTG
NERIMLCERGTSFGYNTLVNDMRGLPIMAATGYPVVYDATHSVQQPGGLGGSSGGQREFAPILARGALAIGVAAVFIETH
QDPDSAPSDGPNMIPIRDMKALVQRLAQYDRLTKAGTP
>Mature_277_residues
THPKSVSLGSLTVGNDRPFVLIAGPCQIESEAHAMETADALHGIARETGVGLIYKSSFDKANRTSLGAARGVGMAAGLEI
LARVRERFGVPVLTDVHAADQCAPTAAAVDVLQIPAFLCRQTDLLLAAGETGAAINVKKGQFLAPWDMTNVAAKIASTGN
ERIMLCERGTSFGYNTLVNDMRGLPIMAATGYPVVYDATHSVQQPGGLGGSSGGQREFAPILARGALAIGVAAVFIETHQ
DPDSAPSDGPNMIPIRDMKALVQRLAQYDRLTKAGTP

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=272, Percent_Identity=43.0147058823529, Blast_Score=244, Evalue=5e-66,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 29094; Mature: 28962

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPKSVSLGSLTVGNDRPFVLIAGPCQIESEAHAMETADALHGIARETGVGLIYKSSFD
CCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCC
KANRTSLGAARGVGMAAGLEILARVRERFGVPVLTDVHAADQCAPTAAAVDVLQIPAFLC
CCCCHHCCHHHCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHH
RQTDLLLAAGETGAAINVKKGQFLAPWDMTNVAAKIASTGNERIMLCERGTSFGYNTLVN
CCCCEEEEECCCCCEEEECCCCEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
DMRGLPIMAATGYPVVYDATHSVQQPGGLGGSSGGQREFAPILARGALAIGVAAVFIETH
HHCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECC
QDPDSAPSDGPNMIPIRDMKALVQRLAQYDRLTKAGTP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
THPKSVSLGSLTVGNDRPFVLIAGPCQIESEAHAMETADALHGIARETGVGLIYKSSFD
CCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCC
KANRTSLGAARGVGMAAGLEILARVRERFGVPVLTDVHAADQCAPTAAAVDVLQIPAFLC
CCCCHHCCHHHCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHH
RQTDLLLAAGETGAAINVKKGQFLAPWDMTNVAAKIASTGNERIMLCERGTSFGYNTLVN
CCCCEEEEECCCCCEEEECCCCEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
DMRGLPIMAATGYPVVYDATHSVQQPGGLGGSSGGQREFAPILARGALAIGVAAVFIETH
HHCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECC
QDPDSAPSDGPNMIPIRDMKALVQRLAQYDRLTKAGTP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA