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The map label for this gene is ruvB [H]

Identifier: 162146623

GI number: 162146623

Start: 819485

End: 820531

Strand: Direct

Name: ruvB [H]

Synonym: GDI_0801

Alternate gene names: 162146623

Gene position: 819485-820531 (Clockwise)

Preceding gene: 162146622

Following gene: 162146624

Centisome position: 20.78

GC content: 72.21

Gene sequence:

>1047_bases
ATGACCGAAATCCCCCTCCGCGAGGTCGATCCCGCCCGCAATGCGGAAGATGCTGCCGAAGCCGGGCTGCGGCCGCAGAC
CCTGGACGATTTCACGGGCCAGAAGGCCAGCCGCGAGAACCTGGCCATCTTCATCGCCGCCGCCCGCCAGCGGGGCGAGG
CGATGGACCACGTGCTGCTGCACGGCCCGCCGGGGCTGGGCAAGACCACGCTGGCGCAGATCGTGGCGCGGGAACTGGGG
GTCGGCTTTCGTGCGACCTCGGGCCCCGTGATCCAGCGCGCGGGCGACCTGGCGGCCATCCTGACCAACCTGCAGCCCCG
TGACGTGCTGTTCATCGACGAAATCCACCGCCTGCAGCCGGCGATCGAGGAAGTGCTGTATCCGGCGATGGAGGATTTCC
AGCTCGACCTGATCATCGGCGAGGGGCCGGCGGCGCGCTCGGTGCGCATCGACCTCTCGCCCTTCACCCTGGTGGCCGCG
ACCACGCGGGCCGGGCTGCTGGCCACCCCGCTGCGCGACCGGTTCGGCATTCCGCTGCGGCTGGTGTTCTACACCCCCGA
CGAACTGCGCCAGATCGTCTCGCGCGGGGCGCGGAAGCTGGAATTCGACCTGACGCCGGAAGGGGCCGAGGAAATCGCCC
GCCGGTCGCGCGGCACGCCGCGCATCGCCGGGCGCCTGCTGCGGCGGGTGCGCGACTTCGCCTCGGTCACCCGTGGCGGC
CCGGTGGACCGCGCGATGGCCGACGCCGCCCTGTCGCGGCTGGAAGTCGATTCGCTGGGGCTGGACGGGATGGACCGGCG
CTATCTGCGCCGCATCGCCGAACATCATCACGGCGGCCCGGTGGGGGTGGAAACCCTGGCCGCCGCCCTGGCCGAGGCGC
GAGACACGCTGGAAGACGTGGTCGAACCCTACCTGATCCAGGAGGGGCTGGTCCTGCGTACCAGCCGGGGACGCACGCTG
GGCGAGCGGGGCTGGCGGCATCTGGGGCTTGCCCCCCCGCCACGGCAGACGGGCCAGGGCGACCTGCTGCAGGGGGACGA
CGGGTGA

Upstream 100 bases:

>100_bases
GGGCCGAGGCCCAGCCGGTGGTGGGGCGCATCCTGGCGCGCCTGGACGGCAAGGCGGACCTGGATGTCGTGATCCGCGAA
AGCCTGCGGGAACTTGCCCG

Downstream 100 bases:

>100_bases
GGCACAACATTCCTTTCCGCATTTATTACGAAGATACGGACGCCGGCGGCGTGGTCTACCACGCCCGGTATCTCGGCCTG
GCCGAGCGCGCGCGGACCGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTEIPLREVDPARNAEDAAEAGLRPQTLDDFTGQKASRENLAIFIAAARQRGEAMDHVLLHGPPGLGKTTLAQIVARELG
VGFRATSGPVIQRAGDLAAILTNLQPRDVLFIDEIHRLQPAIEEVLYPAMEDFQLDLIIGEGPAARSVRIDLSPFTLVAA
TTRAGLLATPLRDRFGIPLRLVFYTPDELRQIVSRGARKLEFDLTPEGAEEIARRSRGTPRIAGRLLRRVRDFASVTRGG
PVDRAMADAALSRLEVDSLGLDGMDRRYLRRIAEHHHGGPVGVETLAAALAEARDTLEDVVEPYLIQEGLVLRTSRGRTL
GERGWRHLGLAPPPRQTGQGDLLQGDDG

Sequences:

>Translated_348_residues
MTEIPLREVDPARNAEDAAEAGLRPQTLDDFTGQKASRENLAIFIAAARQRGEAMDHVLLHGPPGLGKTTLAQIVARELG
VGFRATSGPVIQRAGDLAAILTNLQPRDVLFIDEIHRLQPAIEEVLYPAMEDFQLDLIIGEGPAARSVRIDLSPFTLVAA
TTRAGLLATPLRDRFGIPLRLVFYTPDELRQIVSRGARKLEFDLTPEGAEEIARRSRGTPRIAGRLLRRVRDFASVTRGG
PVDRAMADAALSRLEVDSLGLDGMDRRYLRRIAEHHHGGPVGVETLAAALAEARDTLEDVVEPYLIQEGLVLRTSRGRTL
GERGWRHLGLAPPPRQTGQGDLLQGDDG
>Mature_347_residues
TEIPLREVDPARNAEDAAEAGLRPQTLDDFTGQKASRENLAIFIAAARQRGEAMDHVLLHGPPGLGKTTLAQIVARELGV
GFRATSGPVIQRAGDLAAILTNLQPRDVLFIDEIHRLQPAIEEVLYPAMEDFQLDLIIGEGPAARSVRIDLSPFTLVAAT
TRAGLLATPLRDRFGIPLRLVFYTPDELRQIVSRGARKLEFDLTPEGAEEIARRSRGTPRIAGRLLRRVRDFASVTRGGP
VDRAMADAALSRLEVDSLGLDGMDRRYLRRIAEHHHGGPVGVETLAAALAEARDTLEDVVEPYLIQEGLVLRTSRGRTLG
ERGWRHLGLAPPPRQTGQGDLLQGDDG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=318, Percent_Identity=60.062893081761, Blast_Score=391, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37998; Mature: 37867

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIPLREVDPARNAEDAAEAGLRPQTLDDFTGQKASRENLAIFIAAARQRGEAMDHVLL
CCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCCCCCCCCEEEEEEEHHHHCHHHCEEEE
HGPPGLGKTTLAQIVARELGVGFRATSGPVIQRAGDLAAILTNLQPRDVLFIDEIHRLQP
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHH
AIEEVLYPAMEDFQLDLIIGEGPAARSVRIDLSPFTLVAATTRAGLLATPLRDRFGIPLR
HHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCEEEEHHHHCCHHCCCHHHHCCCCEE
LVFYTPDELRQIVSRGARKLEFDLTPEGAEEIARRSRGTPRIAGRLLRRVRDFASVTRGG
EEEECHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
PVDRAMADAALSRLEVDSLGLDGMDRRYLRRIAEHHHGGPVGVETLAAALAEARDTLEDV
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
VEPYLIQEGLVLRTSRGRTLGERGWRHLGLAPPPRQTGQGDLLQGDDG
HHHHHHHCCEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEIPLREVDPARNAEDAAEAGLRPQTLDDFTGQKASRENLAIFIAAARQRGEAMDHVLL
CCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCCCCCCCCEEEEEEEHHHHCHHHCEEEE
HGPPGLGKTTLAQIVARELGVGFRATSGPVIQRAGDLAAILTNLQPRDVLFIDEIHRLQP
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHH
AIEEVLYPAMEDFQLDLIIGEGPAARSVRIDLSPFTLVAATTRAGLLATPLRDRFGIPLR
HHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCEEEEHHHHCCHHCCCHHHHCCCCEE
LVFYTPDELRQIVSRGARKLEFDLTPEGAEEIARRSRGTPRIAGRLLRRVRDFASVTRGG
EEEECHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
PVDRAMADAALSRLEVDSLGLDGMDRRYLRRIAEHHHGGPVGVETLAAALAEARDTLEDV
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
VEPYLIQEGLVLRTSRGRTLGERGWRHLGLAPPPRQTGQGDLLQGDDG
HHHHHHHCCEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA