Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 162146622

GI number: 162146622

Start: 818886

End: 819488

Strand: Direct

Name: ruvA

Synonym: GDI_0800

Alternate gene names: 162146622

Gene position: 818886-819488 (Clockwise)

Preceding gene: 162146621

Following gene: 162146623

Centisome position: 20.76

GC content: 73.47

Gene sequence:

>603_bases
ATGATCGCGCACCTGACCGGGCTGGTGGGGCAGATGGAATCCGACCGCTGCGTGGTCGATGTCGGCGGCGTCGGCTATCT
GGTCCATGCCTCCACCCGCACGCTCTCGGCGCTGCCCCGTCCGCCCGATGTGACCCGCGTCCTGGTCGAGACCGTGGTGC
GCGAGGATGCCTTCCTGCTCTACGGCTTTGCGGAAGCCGCGGAGCGCGACTGGTTCCGCCTGCTGACGACGGTCCAGGGG
GTGGGGGCGAAGGTCGCGCTGGCCATTCTCTCCGCCCTGTCGCCGGGCGACCTGGCCGGGGTGATCGCGGCGGCGGACAA
GGCCAGCCTGACCCGGGTGTCGGGTGTCGGCGCGCGGCTGGCCGAGCGCATCCTGACCGAACTGCGCGACAAGGCCGGGC
GCATGCCCGCCGGGCCGGGCGTGACGATCGCGGCCCCCCCGGCCTCGGGCGGGGTGGAAGCCGATGCCCTGCTGGCGCTG
GCGGGCCTGGGCTTCCGCCGGGCCGAGGCCCAGCCGGTGGTGGGGCGCATCCTGGCGCGCCTGGACGGCAAGGCGGACCT
GGATGTCGTGATCCGCGAAAGCCTGCGGGAACTTGCCCGATGA

Upstream 100 bases:

>100_bases
CGATCCGCCGGGCGGACGCGTCCGATGCGCTGGCGGTGGCGATCTGCCATGCCCATCACCGGGCCAGCGCCCTGCGGGTG
TCGGCCGGGACCCGCATGGC

Downstream 100 bases:

>100_bases
CCGAAATCCCCCTCCGCGAGGTCGATCCCGCCCGCAATGCGGAAGATGCTGCCGAAGCCGGGCTGCGGCCGCAGACCCTG
GACGATTTCACGGGCCAGAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MIAHLTGLVGQMESDRCVVDVGGVGYLVHASTRTLSALPRPPDVTRVLVETVVREDAFLLYGFAEAAERDWFRLLTTVQG
VGAKVALAILSALSPGDLAGVIAAADKASLTRVSGVGARLAERILTELRDKAGRMPAGPGVTIAAPPASGGVEADALLAL
AGLGFRRAEAQPVVGRILARLDGKADLDVVIRESLRELAR

Sequences:

>Translated_200_residues
MIAHLTGLVGQMESDRCVVDVGGVGYLVHASTRTLSALPRPPDVTRVLVETVVREDAFLLYGFAEAAERDWFRLLTTVQG
VGAKVALAILSALSPGDLAGVIAAADKASLTRVSGVGARLAERILTELRDKAGRMPAGPGVTIAAPPASGGVEADALLAL
AGLGFRRAEAQPVVGRILARLDGKADLDVVIRESLRELAR
>Mature_200_residues
MIAHLTGLVGQMESDRCVVDVGGVGYLVHASTRTLSALPRPPDVTRVLVETVVREDAFLLYGFAEAAERDWFRLLTTVQG
VGAKVALAILSALSPGDLAGVIAAADKASLTRVSGVGARLAERILTELRDKAGRMPAGPGVTIAAPPASGGVEADALLAL
AGLGFRRAEAQPVVGRILARLDGKADLDVVIRESLRELAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=36.9458128078818, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_GLUDA (A9HAV7)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001601081.1
- RefSeq:   YP_002275615.1
- ProteinModelPortal:   A9HAV7
- SMR:   A9HAV7
- GeneID:   5788774
- GeneID:   6974621
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_1217
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20825; Mature: 20825

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAHLTGLVGQMESDRCVVDVGGVGYLVHASTRTLSALPRPPDVTRVLVETVVREDAFLL
CCCHHHHHHHCCCCCCEEEEECCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCHHEE
YGFAEAAERDWFRLLTTVQGVGAKVALAILSALSPGDLAGVIAAADKASLTRVSGVGARL
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
AERILTELRDKAGRMPAGPGVTIAAPPASGGVEADALLALAGLGFRRAEAQPVVGRILAR
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHH
LDGKADLDVVIRESLRELAR
HCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAHLTGLVGQMESDRCVVDVGGVGYLVHASTRTLSALPRPPDVTRVLVETVVREDAFLL
CCCHHHHHHHCCCCCCEEEEECCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCHHEE
YGFAEAAERDWFRLLTTVQGVGAKVALAILSALSPGDLAGVIAAADKASLTRVSGVGARL
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
AERILTELRDKAGRMPAGPGVTIAAPPASGGVEADALLALAGLGFRRAEAQPVVGRILAR
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHH
LDGKADLDVVIRESLRELAR
HCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA