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The map label for this gene is ahpC [H]

Identifier: 162146596

GI number: 162146596

Start: 791702

End: 792364

Strand: Reverse

Name: ahpC [H]

Synonym: GDI_0774

Alternate gene names: 162146596

Gene position: 792364-791702 (Counterclockwise)

Preceding gene: 162146600

Following gene: 162146595

Centisome position: 20.09

GC content: 57.32

Gene sequence:

>663_bases
ATGGTTTTACCTATAATTCCCATCGGGACAAACGATTTCCGCCCGAGGGAAATTTGTCGGACACCCGTTCTGTCATCAAC
GCACAGAAGGACAGAACTTATGACGACGATAAACTCCGAACTGAAGTCATTCAGCACCGATGCCTTCCATAACGGCGAAT
TTATCAAGGTATCGGACCAGGATGTGAGGGGAAAATGGGCCGTCTTTTTCTTCTATCCGGCGGATTTCACCTTCGTCTGC
CCGACAGAACTGGAAGATATGGCCGATCATTACGCCACTTTCCAGGATCTGGGCGTCGAGATCTACGCCGTTTCCACCGA
CAAGCATTTCACGCACAAGGCCTGGCATGACACGTCGCCGGCGATCGGCAAGATCCGCTACGTCATGCTTGGCGACCCCA
CGGGCGCGATCTCCCGCAATTTCGGCGTGCTGGTCGAGGACGCCGGCGTCGCGAACCGCGGCACCTTCCTGATCGATCCG
CAGGGGCGGGTGCAATATATGGAAATCACCGCCGAAGGCGTCGGCCGGACGGCCGAAAGCCTGATCGACAAGATCAAGGC
CGCCCAATACATCGCTGCTCATCCCGGCGAAGTCTGCCCCGCCAAGTGGAAGGAGGACGGCGCGACCCTGACCCCGTCCC
TGGATCTGATCGGCAAGATCTGA

Upstream 100 bases:

>100_bases
CATCGACGGCCACGGCATATTCGATGTCGCGCAGCGACAGGCCAGACAGGGGAGTGTAGGTCTTTTCCATAAGTACGATC
GCTCAATCCAATCCCATAAA

Downstream 100 bases:

>100_bases
CCCCAGCCACAGGCCCGGCCCATGCGGCCGGGCAACCGCCCCACTTCACTGGAATACGGAATCCTCCCGATGCTGCAGGA
TACGATCAAGTCACAACTCA

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MVLPIIPIGTNDFRPREICRTPVLSSTHRRTELMTTINSELKSFSTDAFHNGEFIKVSDQDVRGKWAVFFFYPADFTFVC
PTELEDMADHYATFQDLGVEIYAVSTDKHFTHKAWHDTSPAIGKIRYVMLGDPTGAISRNFGVLVEDAGVANRGTFLIDP
QGRVQYMEITAEGVGRTAESLIDKIKAAQYIAAHPGEVCPAKWKEDGATLTPSLDLIGKI

Sequences:

>Translated_220_residues
MVLPIIPIGTNDFRPREICRTPVLSSTHRRTELMTTINSELKSFSTDAFHNGEFIKVSDQDVRGKWAVFFFYPADFTFVC
PTELEDMADHYATFQDLGVEIYAVSTDKHFTHKAWHDTSPAIGKIRYVMLGDPTGAISRNFGVLVEDAGVANRGTFLIDP
QGRVQYMEITAEGVGRTAESLIDKIKAAQYIAAHPGEVCPAKWKEDGATLTPSLDLIGKI
>Mature_220_residues
MVLPIIPIGTNDFRPREICRTPVLSSTHRRTELMTTINSELKSFSTDAFHNGEFIKVSDQDVRGKWAVFFFYPADFTFVC
PTELEDMADHYATFQDLGVEIYAVSTDKHFTHKAWHDTSPAIGKIRYVMLGDPTGAISRNFGVLVEDAGVANRGTFLIDP
QGRVQYMEITAEGVGRTAESLIDKIKAAQYIAAHPGEVCPAKWKEDGATLTPSLDLIGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=214, Percent_Identity=41.588785046729, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI5802974, Length=225, Percent_Identity=40, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI5453549, Length=173, Percent_Identity=42.1965317919075, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=40, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI4505591, Length=173, Percent_Identity=36.9942196531792, Blast_Score=131, Evalue=4e-31,
Organism=Homo sapiens, GI32455266, Length=173, Percent_Identity=36.9942196531792, Blast_Score=131, Evalue=4e-31,
Organism=Homo sapiens, GI32455264, Length=173, Percent_Identity=36.9942196531792, Blast_Score=131, Evalue=4e-31,
Organism=Homo sapiens, GI33188454, Length=77, Percent_Identity=45.4545454545455, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=65.24064171123, Blast_Score=279, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17554494, Length=209, Percent_Identity=39.7129186602871, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI193204376, Length=175, Percent_Identity=40, Blast_Score=137, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI32565831, Length=175, Percent_Identity=40, Blast_Score=137, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6323613, Length=186, Percent_Identity=31.7204301075269, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320661, Length=185, Percent_Identity=30.2702702702703, Blast_Score=112, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=209, Percent_Identity=27.7511961722488, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357347, Length=180, Percent_Identity=37.2222222222222, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=38.9830508474576, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24656348, Length=189, Percent_Identity=37.5661375661376, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI17864676, Length=189, Percent_Identity=37.5661375661376, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=36.1111111111111, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=36.1111111111111, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=27.8481012658228, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24443; Mature: 24443

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPIIPIGTNDFRPREICRTPVLSSTHRRTELMTTINSELKSFSTDAFHNGEFIKVSDQ
CEEEEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
DVRGKWAVFFFYPADFTFVCPTELEDMADHYATFQDLGVEIYAVSTDKHFTHKAWHDTSP
CCCCEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCC
AIGKIRYVMLGDPTGAISRNFGVLVEDAGVANRGTFLIDPQGRVQYMEITAEGVGRTAES
CCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCHHHHH
LIDKIKAAQYIAAHPGEVCPAKWKEDGATLTPSLDLIGKI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCHHHEECC
>Mature Secondary Structure
MVLPIIPIGTNDFRPREICRTPVLSSTHRRTELMTTINSELKSFSTDAFHNGEFIKVSDQ
CEEEEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
DVRGKWAVFFFYPADFTFVCPTELEDMADHYATFQDLGVEIYAVSTDKHFTHKAWHDTSP
CCCCEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCC
AIGKIRYVMLGDPTGAISRNFGVLVEDAGVANRGTFLIDPQGRVQYMEITAEGVGRTAES
CCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCHHHHH
LIDKIKAAQYIAAHPGEVCPAKWKEDGATLTPSLDLIGKI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]