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The map label for this gene is glnS [H]

Identifier: 161870414

GI number: 161870414

Start: 1489423

End: 1490949

Strand: Reverse

Name: glnS [H]

Synonym: NMCC_1462

Alternate gene names: 161870414

Gene position: 1490949-1489423 (Counterclockwise)

Preceding gene: 161870415

Following gene: 161870413

Centisome position: 69.24

GC content: 54.22

Gene sequence:

>1527_bases
TTGGCGTATATTTATGACGGCTTGTGCAACCTGCGTTTCGACGATACCAATCCTGAAAAAGAAAACGACGAATACGTCAA
CGCCATCAAAGAAGACGTTGAGTGGTTGGGTTTCCATTGGGCAGGCGAGCCGCGTTTCGCTTCCAACTATTTCGACCAGC
TTTATGACTACGCCGTCGGTTTGATTAAAGACGGCAAAGCGTATGTCGATGATTTGACGCCCGAAGAAATGCGCGAATAC
CGCGGTACGCTGACCGAAGCGGGTAAAAACAGCCCTTACCGCGACCGCAGCGTCGAAGAAAACCTCGACCTGTTCACACG
CATGAAAAACGGCGAGTTCCCCGACGGCAGCAAAACCCTGCGCCTGAAAATCGACATGGCATCGGGCAACATCAATATGC
GCGACCCCGTCATCTACCGCATCCGCCGCGCCCATCACCACAACACCGGCGACAAATGGTGTATCTACCCGATGTACGAC
TACACGCATTGCATCTCCGATGCCATCGAAGGCATCACGCATTCCTTGTGTACGCTCGAATTTGAAGCACACCGTCCGCT
GTACGACTGGGTGTTGGATAACATCCACGCGCCGCATGCCACCCGTCCGCGCCAATACGAGTTTTCCCGTTTGGAGCTTT
TGTACACCATTACCTCCAAACGGAAATTGAATCAGTTGGTTGTGGAAAAACACGTTTCCGGCTGGGACGATCCGCGTATG
CCGACTATTTCCGGTATGCGCCGACGCGGCTACACGCCCGAAGGCCTGCGTCTGTTTGCCAAACGCGCCGGTATTTCCAA
ATCTGAAAACATCGTCGATATGAGCGTGTTGGAAGGCGCGATTCGCGAAGAGTTGGAAAATTCCGCCCCACGCCTGATGG
CGGTGTTGAACCCGCTCAAAGTGACCCTGACCAACTTTGAAGCCGGCAGAACCCAAAGCCGCCGTGCCGCGTTCCATCCG
AACCACGAGGAAATGGGCGAGCGCGAAGTACCTATTTCACAAACCATCTATATTGAAGCCGACGACTTTGCCGAAAATCC
GCCCAAAGGCTTCAAACGCCTGATTCCCGGCGGCGAAGTACGCTTGCGCCACGGCTATGTCATCAAGTGCGATGAAGTCG
TCAAAGACGAAGCAGGCAATGTGGTTGAACTCAAATGCAGCATCGACCACGACACCTTGGGCAAAAATCCAGAAGGCCGT
AAAGTTAAAGGCGTGATTCATTGGGTTTCCGCCGAACACGCCGCCGAAATCAAAGTCCGTCTGTACGACCGCCTCTTTAC
CATCGAGCGTCCCGATGCCGTGCGCGGCGAAGACGGCGAATACCTGCCGTTCACCGATTTCCTCAATCCGGAATCCGTCA
AGGAAATCACCGCCTACGCCGAACCTGCCGCCAAAGATTTGCCGGCAGAAAGCCGTTGGCAGTTCGAGCGTATCGGCTAC
TTCGTAACCGACCGTAAAGACCACGGCAAAGACACGCCGGTGTTTAACCGCACGGTCACGCTGAAAGATTCTTGGCAGCC
TAAGTAA

Upstream 100 bases:

>100_bases
CAAAAGCGGCAAACACGAAGCCGTCCAAACCCGTTTTCCGCCGGAGCCCAACGGCTACCTGCACATCGGACACGCCAAAT
CCATCTGCCTGAACTTCGGT

Downstream 100 bases:

>100_bases
AACCCCATCCTTGCCGTCTGAATATTGTTCGGACGGCATTTCCCCTTTGCCCGCGAAATGCGGCACATTCGGCACACCGG
AAAGGAAATATGATGAAAGT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MAYIYDGLCNLRFDDTNPEKENDEYVNAIKEDVEWLGFHWAGEPRFASNYFDQLYDYAVGLIKDGKAYVDDLTPEEMREY
RGTLTEAGKNSPYRDRSVEENLDLFTRMKNGEFPDGSKTLRLKIDMASGNINMRDPVIYRIRRAHHHNTGDKWCIYPMYD
YTHCISDAIEGITHSLCTLEFEAHRPLYDWVLDNIHAPHATRPRQYEFSRLELLYTITSKRKLNQLVVEKHVSGWDDPRM
PTISGMRRRGYTPEGLRLFAKRAGISKSENIVDMSVLEGAIREELENSAPRLMAVLNPLKVTLTNFEAGRTQSRRAAFHP
NHEEMGEREVPISQTIYIEADDFAENPPKGFKRLIPGGEVRLRHGYVIKCDEVVKDEAGNVVELKCSIDHDTLGKNPEGR
KVKGVIHWVSAEHAAEIKVRLYDRLFTIERPDAVRGEDGEYLPFTDFLNPESVKEITAYAEPAAKDLPAESRWQFERIGY
FVTDRKDHGKDTPVFNRTVTLKDSWQPK

Sequences:

>Translated_508_residues
MAYIYDGLCNLRFDDTNPEKENDEYVNAIKEDVEWLGFHWAGEPRFASNYFDQLYDYAVGLIKDGKAYVDDLTPEEMREY
RGTLTEAGKNSPYRDRSVEENLDLFTRMKNGEFPDGSKTLRLKIDMASGNINMRDPVIYRIRRAHHHNTGDKWCIYPMYD
YTHCISDAIEGITHSLCTLEFEAHRPLYDWVLDNIHAPHATRPRQYEFSRLELLYTITSKRKLNQLVVEKHVSGWDDPRM
PTISGMRRRGYTPEGLRLFAKRAGISKSENIVDMSVLEGAIREELENSAPRLMAVLNPLKVTLTNFEAGRTQSRRAAFHP
NHEEMGEREVPISQTIYIEADDFAENPPKGFKRLIPGGEVRLRHGYVIKCDEVVKDEAGNVVELKCSIDHDTLGKNPEGR
KVKGVIHWVSAEHAAEIKVRLYDRLFTIERPDAVRGEDGEYLPFTDFLNPESVKEITAYAEPAAKDLPAESRWQFERIGY
FVTDRKDHGKDTPVFNRTVTLKDSWQPK
>Mature_507_residues
AYIYDGLCNLRFDDTNPEKENDEYVNAIKEDVEWLGFHWAGEPRFASNYFDQLYDYAVGLIKDGKAYVDDLTPEEMREYR
GTLTEAGKNSPYRDRSVEENLDLFTRMKNGEFPDGSKTLRLKIDMASGNINMRDPVIYRIRRAHHHNTGDKWCIYPMYDY
THCISDAIEGITHSLCTLEFEAHRPLYDWVLDNIHAPHATRPRQYEFSRLELLYTITSKRKLNQLVVEKHVSGWDDPRMP
TISGMRRRGYTPEGLRLFAKRAGISKSENIVDMSVLEGAIREELENSAPRLMAVLNPLKVTLTNFEAGRTQSRRAAFHPN
HEEMGEREVPISQTIYIEADDFAENPPKGFKRLIPGGEVRLRHGYVIKCDEVVKDEAGNVVELKCSIDHDTLGKNPEGRK
VKGVIHWVSAEHAAEIKVRLYDRLFTIERPDAVRGEDGEYLPFTDFLNPESVKEITAYAEPAAKDLPAESRWQFERIGYF
VTDRKDHGKDTPVFNRTVTLKDSWQPK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=502, Percent_Identity=43.8247011952191, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI62241042, Length=482, Percent_Identity=33.402489626556, Blast_Score=234, Evalue=1e-61,
Organism=Escherichia coli, GI1786895, Length=506, Percent_Identity=59.0909090909091, Blast_Score=612, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17543332, Length=504, Percent_Identity=41.8650793650794, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17511007, Length=489, Percent_Identity=31.6973415132924, Blast_Score=223, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324742, Length=539, Percent_Identity=38.961038961039, Blast_Score=329, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6321192, Length=493, Percent_Identity=36.7139959432049, Blast_Score=267, Evalue=2e-72,
Organism=Drosophila melanogaster, GI17864488, Length=506, Percent_Identity=41.304347826087, Blast_Score=374, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24649466, Length=489, Percent_Identity=33.7423312883436, Blast_Score=227, Evalue=1e-59,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 58642; Mature: 58510

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYIYDGLCNLRFDDTNPEKENDEYVNAIKEDVEWLGFHWAGEPRFASNYFDQLYDYAVG
CCEEECCCEECEECCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHH
LIKDGKAYVDDLTPEEMREYRGTLTEAGKNSPYRDRSVEENLDLFTRMKNGEFPDGSKTL
HHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEE
RLKIDMASGNINMRDPVIYRIRRAHHHNTGDKWCIYPMYDYTHCISDAIEGITHSLCTLE
EEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEE
FEAHRPLYDWVLDNIHAPHATRPRQYEFSRLELLYTITSKRKLNQLVVEKHVSGWDDPRM
ECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCC
PTISGMRRRGYTPEGLRLFAKRAGISKSENIVDMSVLEGAIREELENSAPRLMAVLNPLK
CCHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHCCEE
VTLTNFEAGRTQSRRAAFHPNHEEMGEREVPISQTIYIEADDFAENPPKGFKRLIPGGEV
EEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCE
RLRHGYVIKCDEVVKDEAGNVVELKCSIDHDTLGKNPEGRKVKGVIHWVSAEHAAEIKVR
EEECCEEEEEHHHHHCCCCCEEEEEEECCHHCCCCCCCCCEEEEEEEEECCCCHHHEEEE
LYDRLFTIERPDAVRGEDGEYLPFTDFLNPESVKEITAYAEPAAKDLPAESRWQFERIGY
EEEHHEEECCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHCCE
FVTDRKDHGKDTPVFNRTVTLKDSWQPK
EEECCCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
AYIYDGLCNLRFDDTNPEKENDEYVNAIKEDVEWLGFHWAGEPRFASNYFDQLYDYAVG
CEEECCCEECEECCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHH
LIKDGKAYVDDLTPEEMREYRGTLTEAGKNSPYRDRSVEENLDLFTRMKNGEFPDGSKTL
HHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEE
RLKIDMASGNINMRDPVIYRIRRAHHHNTGDKWCIYPMYDYTHCISDAIEGITHSLCTLE
EEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEE
FEAHRPLYDWVLDNIHAPHATRPRQYEFSRLELLYTITSKRKLNQLVVEKHVSGWDDPRM
ECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCC
PTISGMRRRGYTPEGLRLFAKRAGISKSENIVDMSVLEGAIREELENSAPRLMAVLNPLK
CCHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHCCEE
VTLTNFEAGRTQSRRAAFHPNHEEMGEREVPISQTIYIEADDFAENPPKGFKRLIPGGEV
EEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCE
RLRHGYVIKCDEVVKDEAGNVVELKCSIDHDTLGKNPEGRKVKGVIHWVSAEHAAEIKVR
EEECCEEEEEHHHHHCCCCCEEEEEEECCHHCCCCCCCCCEEEEEEEEECCCCHHHEEEE
LYDRLFTIERPDAVRGEDGEYLPFTDFLNPESVKEITAYAEPAAKDLPAESRWQFERIGY
EEEHHEEECCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHCCE
FVTDRKDHGKDTPVFNRTVTLKDSWQPK
EEECCCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA