Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 161870415

GI number: 161870415

Start: 1491223

End: 1491996

Strand: Reverse

Name: glpR [H]

Synonym: NMCC_1463

Alternate gene names: 161870415

Gene position: 1491996-1491223 (Counterclockwise)

Preceding gene: 161870416

Following gene: 161870414

Centisome position: 69.29

GC content: 57.62

Gene sequence:

>774_bases
ATGAAACCGAAAATCCAAAGGCACGGAGAGATTTTAAGCCTTGTCCGCCGGCATCAGTTTATGTCGGTGGACGAGCTTGC
CGCCGCATTGGACGTTACCCCGCAGACGATACGCCGCGACATCCGCGAATTGGAGGATGCTGGCAGCCTGAAACGCCACC
ACGGCGGCGCATCCTCGGGCGGAAACTTGCCGGAGGGGCTGCCTGCCAGCCGCCAAATTCAATGTCAAAACGAAAAAAAC
GCCATTGCCCGGCTGATTGCGGAACATATTCCCGACGAGTCATCGCTGTTTGTCAGTATCGGCACGACGATGGAAGCCGT
GGCATCGGAGCTGGTGAGACGGCGCGGCAGCCTGCGGATTATTACCAACAATATCCACGTCGCCTCCATCGTTTCGGCGC
GGACGGATTACACGGTCATCATCACTTCCGGAGTCGTCCGCCCTTTGGACGGCGGCATTACCGGCGTGGCAACCGTCGAT
TTTATCAACCAGTTCAAAGTCGATTATGCCGTGATGAGTACGCACGGCGTGGAAAGCGACGGTTCGCTTTTGGACGACGA
CTACAAAGAAGTCAGCGTGATGCAGGCGATGATTGCCAACGCGCGCGTCCGCTTCCTCGGCGTGGACCACAGTAAATTCC
GCAGCAACGCGCTGGTCAGGCTCGGCGACATTACGGCGTTTGACAAAGTATTTACCGACCGGCTGCCCGATACCGCGATG
CAGAAGATGCTGAAAGAGGCGGGGGTGGAATGCCTGATTGCCGATGCCGTCTGA

Upstream 100 bases:

>100_bases
CGTGGTGGTCAATATCGCCGCTCCGTTTCTGATGGTGGTGTTTTCCGCTTTGGGCTGAACGCGGTAAAATCGGCATCCCG
ATGCAAGGAGGCAGAAAACG

Downstream 100 bases:

>100_bases
ACGCTATGTCAAAGCGCGCAAGTCGGGTACAATAAACACATCATCAAACCGCTTCAGACGGCATAAGGAACCGCCCCAAT
GCCGTCTGAAGCCATCTGTT

Product: glycerol 3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKPKIQRHGEILSLVRRHQFMSVDELAAALDVTPQTIRRDIRELEDAGSLKRHHGGASSGGNLPEGLPASRQIQCQNEKN
AIARLIAEHIPDESSLFVSIGTTMEAVASELVRRRGSLRIITNNIHVASIVSARTDYTVIITSGVVRPLDGGITGVATVD
FINQFKVDYAVMSTHGVESDGSLLDDDYKEVSVMQAMIANARVRFLGVDHSKFRSNALVRLGDITAFDKVFTDRLPDTAM
QKMLKEAGVECLIADAV

Sequences:

>Translated_257_residues
MKPKIQRHGEILSLVRRHQFMSVDELAAALDVTPQTIRRDIRELEDAGSLKRHHGGASSGGNLPEGLPASRQIQCQNEKN
AIARLIAEHIPDESSLFVSIGTTMEAVASELVRRRGSLRIITNNIHVASIVSARTDYTVIITSGVVRPLDGGITGVATVD
FINQFKVDYAVMSTHGVESDGSLLDDDYKEVSVMQAMIANARVRFLGVDHSKFRSNALVRLGDITAFDKVFTDRLPDTAM
QKMLKEAGVECLIADAV
>Mature_257_residues
MKPKIQRHGEILSLVRRHQFMSVDELAAALDVTPQTIRRDIRELEDAGSLKRHHGGASSGGNLPEGLPASRQIQCQNEKN
AIARLIAEHIPDESSLFVSIGTTMEAVASELVRRRGSLRIITNNIHVASIVSARTDYTVIITSGVVRPLDGGITGVATVD
FINQFKVDYAVMSTHGVESDGSLLDDDYKEVSVMQAMIANARVRFLGVDHSKFRSNALVRLGDITAFDKVFTDRLPDTAM
QKMLKEAGVECLIADAV

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=251, Percent_Identity=43.4262948207171, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI87082344, Length=247, Percent_Identity=38.4615384615385, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1788069, Length=255, Percent_Identity=30.5882352941176, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1789059, Length=257, Percent_Identity=28.4046692607004, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI226510968, Length=247, Percent_Identity=27.9352226720648, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=22.7467811158798, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28093; Mature: 28093

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKIQRHGEILSLVRRHQFMSVDELAAALDVTPQTIRRDIRELEDAGSLKRHHGGASSG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCCC
GNLPEGLPASRQIQCQNEKNAIARLIAEHIPDESSLFVSIGTTMEAVASELVRRRGSLRI
CCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCEEE
ITNNIHVASIVSARTDYTVIITSGVVRPLDGGITGVATVDFINQFKVDYAVMSTHGVESD
EECCEEEEHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCC
GSLLDDDYKEVSVMQAMIANARVRFLGVDHSKFRSNALVRLGDITAFDKVFTDRLPDTAM
CCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCEEEECCHHHHHHHHHHCCCHHHH
QKMLKEAGVECLIADAV
HHHHHHCCCEEEEECCC
>Mature Secondary Structure
MKPKIQRHGEILSLVRRHQFMSVDELAAALDVTPQTIRRDIRELEDAGSLKRHHGGASSG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCCC
GNLPEGLPASRQIQCQNEKNAIARLIAEHIPDESSLFVSIGTTMEAVASELVRRRGSLRI
CCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCEEE
ITNNIHVASIVSARTDYTVIITSGVVRPLDGGITGVATVDFINQFKVDYAVMSTHGVESD
EECCEEEEHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCC
GSLLDDDYKEVSVMQAMIANARVRFLGVDHSKFRSNALVRLGDITAFDKVFTDRLPDTAM
CCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCEEEECCHHHHHHHHHHCCCHHHH
QKMLKEAGVECLIADAV
HHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]