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The map label for this gene is sucD [H]

Identifier: 161869872

GI number: 161869872

Start: 905587

End: 906477

Strand: Direct

Name: sucD [H]

Synonym: NMCC_0903

Alternate gene names: 161869872

Gene position: 905587-906477 (Clockwise)

Preceding gene: 161869871

Following gene: 161869876

Centisome position: 42.05

GC content: 51.52

Gene sequence:

>891_bases
ATGAGCGTATTGATTAATAAAGACACCAAAGTATTGGTTCAAGGTTTCACCGGTAAAAACGGTACTTTCCACTCCGAACA
AGCTCTGGCTTACGGCACTAAAGTTGTCGGCGGCGTTACCCCAGGCAAAGGCGGTCAAACCCACCTGAACCTGCCTGTAT
TCAACACCATGAAAGAAGCCGTTAAAGAAACCGGCGCGGACGCATCTGTCATTTACGTTCCAGCTCCGTTTGTTTTGGAC
TCTATCGTTGAAGCCGTTGATTCAGGCGTAGGCTTGGTCGTTGTGATTACCGAAGGCGTGCCCACTTTGGACATGCTCAA
AGCCAAACGTTACTTGGAAACTAACGGCAACGGTACCCGCTTGGTCGGCCCTAACTGCCCGGGCGTGATTACTCCGGGTG
AGTGCAAAATCGGTATTATGCCGGGCCACATCCACACTCCGGGCCGCATCGGTATTATTTCCCGTTCCGGTACATTGACT
TACGAAGCTGTGGCACAAACCACCAAACTGGGCTTGGGTCAATCAACCTGTATCGGTATCGGCGGCGACCCGATTCCTGG
TATGAATCAAATCGACGCACTGAAACTCTTCCAAGAAGACCCGGATACCGACGCCATCATCATGATCGGTGAAATCGGCG
GTACTGCGGAAGAAGAAGCAGCCGAATACATCCAATCCAACGTAACCAAACCTGTTGTAGGTTACATTGCTGGTGTTACC
GCTCCTAAAGGCAAACGCATGGGCCACGCTGGTGCGATTATTTCCGGCGGCAAAGGTACTGCCGAGGAAAAATTCGCCGC
GTTTGAAAAAGCCGGTATCGCCTATACTCGCAGCCCTGCCGAGTTGGGCACGACGATGCTGGAAGTGTTGAAAGCAAAAG
GTTTGGCATAA

Upstream 100 bases:

>100_bases
AAAATCCTGAACGAATCAGGTCTGAAACTGACTTCTGCAGACGGCCTGAATGACGCAGCCGAAAAAATTGTTGCAGCCGT
AAACGCCTAAGGAGAAAAGA

Downstream 100 bases:

>100_bases
TCAGGTTTGACAACTGATTGAACATCAAATGCCGTCTGAAACCGGAAATCGGGTTTCAGACGGCATTTTGTTTGTCATTT
CAAAAAGAGGCAGCCTCAAC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSVLINKDTKVLVQGFTGKNGTFHSEQALAYGTKVVGGVTPGKGGQTHLNLPVFNTMKEAVKETGADASVIYVPAPFVLD
SIVEAVDSGVGLVVVITEGVPTLDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHTPGRIGIISRSGTLT
YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQEDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
APKGKRMGHAGAIISGGKGTAEEKFAAFEKAGIAYTRSPAELGTTMLEVLKAKGLA

Sequences:

>Translated_296_residues
MSVLINKDTKVLVQGFTGKNGTFHSEQALAYGTKVVGGVTPGKGGQTHLNLPVFNTMKEAVKETGADASVIYVPAPFVLD
SIVEAVDSGVGLVVVITEGVPTLDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHTPGRIGIISRSGTLT
YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQEDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
APKGKRMGHAGAIISGGKGTAEEKFAAFEKAGIAYTRSPAELGTTMLEVLKAKGLA
>Mature_295_residues
SVLINKDTKVLVQGFTGKNGTFHSEQALAYGTKVVGGVTPGKGGQTHLNLPVFNTMKEAVKETGADASVIYVPAPFVLDS
IVEAVDSGVGLVVVITEGVPTLDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHTPGRIGIISRSGTLTY
EAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQEDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVTA
PKGKRMGHAGAIISGGKGTAEEKFAAFEKAGIAYTRSPAELGTTMLEVLKAKGLA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=297, Percent_Identity=61.952861952862, Blast_Score=323, Evalue=9e-89,
Organism=Homo sapiens, GI38569423, Length=261, Percent_Identity=29.5019157088123, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38569421, Length=261, Percent_Identity=29.5019157088123, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=72.5085910652921, Blast_Score=435, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17550194, Length=286, Percent_Identity=63.6363636363636, Blast_Score=339, Evalue=8e-94,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=61.0921501706485, Blast_Score=338, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI17551266, Length=317, Percent_Identity=29.3375394321767, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17557344, Length=314, Percent_Identity=28.343949044586, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=295, Percent_Identity=53.8983050847458, Blast_Score=292, Evalue=5e-80,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=58.3333333333333, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=59.4501718213058, Blast_Score=320, Evalue=8e-88,
Organism=Drosophila melanogaster, GI281363477, Length=259, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281363475, Length=259, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281363473, Length=259, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30563; Mature: 30431

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINKDTKVLVQGFTGKNGTFHSEQALAYGTKVVGGVTPGKGGQTHLNLPVFNTMKEA
CEEEECCCCEEEEEECCCCCCCCCCCHHHHHCCEEECCCCCCCCCCEEEECCHHHHHHHH
VKETGADASVIYVPAPFVLDSIVEAVDSGVGLVVVITEGVPTLDMLKAKRYLETNGNGTR
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCE
LVGPNCPGVITPGECKIGIMPGHIHTPGRIGIISRSGTLTYEAVAQTTKLGLGQSTCIGI
EECCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIPGMNQIDALKLFQEDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
APKGKRMGHAGAIISGGKGTAEEKFAAFEKAGIAYTRSPAELGTTMLEVLKAKGLA
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVLINKDTKVLVQGFTGKNGTFHSEQALAYGTKVVGGVTPGKGGQTHLNLPVFNTMKEA
EEEECCCCEEEEEECCCCCCCCCCCHHHHHCCEEECCCCCCCCCCEEEECCHHHHHHHH
VKETGADASVIYVPAPFVLDSIVEAVDSGVGLVVVITEGVPTLDMLKAKRYLETNGNGTR
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCE
LVGPNCPGVITPGECKIGIMPGHIHTPGRIGIISRSGTLTYEAVAQTTKLGLGQSTCIGI
EECCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIPGMNQIDALKLFQEDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
APKGKRMGHAGAIISGGKGTAEEKFAAFEKAGIAYTRSPAELGTTMLEVLKAKGLA
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]