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The map label for this gene is sucC [H]

Identifier: 161869871

GI number: 161869871

Start: 904410

End: 905576

Strand: Direct

Name: sucC [H]

Synonym: NMCC_0902

Alternate gene names: 161869871

Gene position: 904410-905576 (Clockwise)

Preceding gene: 161869870

Following gene: 161869872

Centisome position: 42.0

GC content: 51.24

Gene sequence:

>1167_bases
ATGAATCTACACGAGTATCAGGCTAAAGAACTGCTGGCTGGCTACGGTTTGCCCGTACAAGGCGGTATTTTGGCACGCAA
CGGCGAAGAAGCCGCTGCAGCTTACGACAAATTGGGCGGTAAGTTTGCCGTTGTCAAAGCACAAGTACACGCCGGCGGCC
GCGGTAAAGCGGGCGGCGTAAAAGTCGTCAAAAGCCGCGAAGAAGCCAAAGAAGTGGCTGAAAGCCTGATTGGCACCAAC
TTGGTAACTTACCAAACCGATGCCAACGGCCAACCTGTCAACAGCGTTTTGGTTTGCGAAGACATGTATCCTGTTCAAAC
CGAGCTGTATTTGGGCGCAGTGGTCGATCGTTCTACCCGCCGCATTACATTCATGGCTTCTACCGAAGGCGGCGTGGAAA
TTGAAAAAGTTGCTGCCGAAACTCCTGAAAAAATCTTCAAAGTAACCGTTGATCCTCTGGTCGGCCTGCAACCTTGCCAA
GCGCGCGAAGTGGCGTTCCAACTGGGCTTGAAAGACAAACAAATCAACGAGTTCGTTAAACTGATGACCGGTGCGTACAA
AGCGTTTGTCGACAACGACTTCGCCCTGTTTGAAGTAAACCCGCTGGCAGTTCGCGAAAACGGCGCACTGGCTTGCGTGG
ACGGCAAAATCGGCATCGACAGCAACGCGCTCTACCGCCTGCCAAAAATCGCTGAATTGCGCGACAAATCTCAAGAAAAC
GAACGTGAGCTGAAAGCTTCTGAATTCGACCTGAACTATGTTGCCCTGGAAGGCAACATTGGCTGTATGGTTAATGGTGC
AGGTTTGGCGATGGCCACTATGGACATCATCAAACTCAAAGGCGGCCAACCTGCCAACTTCTTGGACGTTGGCGGTGGCG
CAACCAAAGACCGCGTGGTTGAAGCGTTCAAACTGATTTTGGAAGACAAATCCGTTAAAGGCGTATTGATCAACATCTTC
GGCGGTATCGTACGTTGCGACATGATTGCGGAAGCCATCGTGGCAGCCGTTAAAGAAATCAACGTCAACGTTCCTGTCGT
TGTTCGTTTGGAAGGTAACAACGCCGAACTCGGCGCGAAAATCCTGAACGAATCAGGTCTGAAACTGACTTCTGCAGACG
GCCTGAATGACGCAGCCGAAAAAATTGTTGCAGCCGTAAACGCCTAA

Upstream 100 bases:

>100_bases
CGCGGATGTGGTTGCCTTTCAGTAAATAGTAGGGCCGTCTGAAAATATGGGATTGGCCGCAGGGCGATTCCTAAGACCCA
CTCACCTTAAGGAGAAATCC

Downstream 100 bases:

>100_bases
GGAGAAAAGAATGAGCGTATTGATTAATAAAGACACCAAAGTATTGGTTCAAGGTTTCACCGGTAAAAACGGTACTTTCC
ACTCCGAACAAGCTCTGGCT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKELLAGYGLPVQGGILARNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGVKVVKSREEAKEVAESLIGTN
LVTYQTDANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTRRITFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQ
AREVAFQLGLKDKQINEFVKLMTGAYKAFVDNDFALFEVNPLAVRENGALACVDGKIGIDSNALYRLPKIAELRDKSQEN
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVVEAFKLILEDKSVKGVLINIF
GGIVRCDMIAEAIVAAVKEINVNVPVVVRLEGNNAELGAKILNESGLKLTSADGLNDAAEKIVAAVNA

Sequences:

>Translated_388_residues
MNLHEYQAKELLAGYGLPVQGGILARNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGVKVVKSREEAKEVAESLIGTN
LVTYQTDANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTRRITFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQ
AREVAFQLGLKDKQINEFVKLMTGAYKAFVDNDFALFEVNPLAVRENGALACVDGKIGIDSNALYRLPKIAELRDKSQEN
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVVEAFKLILEDKSVKGVLINIF
GGIVRCDMIAEAIVAAVKEINVNVPVVVRLEGNNAELGAKILNESGLKLTSADGLNDAAEKIVAAVNA
>Mature_388_residues
MNLHEYQAKELLAGYGLPVQGGILARNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGVKVVKSREEAKEVAESLIGTN
LVTYQTDANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTRRITFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQ
AREVAFQLGLKDKQINEFVKLMTGAYKAFVDNDFALFEVNPLAVRENGALACVDGKIGIDSNALYRLPKIAELRDKSQEN
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVVEAFKLILEDKSVKGVLINIF
GGIVRCDMIAEAIVAAVKEINVNVPVVVRLEGNNAELGAKILNESGLKLTSADGLNDAAEKIVAAVNA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=48.2051282051282, Blast_Score=353, Evalue=1e-97,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=44.0104166666667, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=43.2506887052342, Blast_Score=276, Evalue=2e-74,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=63.7305699481865, Blast_Score=478, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17567829, Length=393, Percent_Identity=44.0203562340967, Blast_Score=326, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=42.7848101265823, Blast_Score=311, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=44.0203562340967, Blast_Score=329, Evalue=4e-91,
Organism=Drosophila melanogaster, GI161078106, Length=387, Percent_Identity=43.4108527131783, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24645208, Length=387, Percent_Identity=43.4108527131783, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=43.5567010309278, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=43.5567010309278, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=43.2911392405063, Blast_Score=296, Evalue=2e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41312; Mature: 41312

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKELLAGYGLPVQGGILARNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSREEAKEVAESLIGTNLVTYQTDANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEHEECCCCE
RITFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQAREVAFQLGLKDKQINEFVK
EEEEEEECCCCCEEHHHHHCCCHHHEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHH
LMTGAYKAFVDNDFALFEVNPLAVRENGALACVDGKIGIDSNALYRLPKIAELRDKSQEN
HHHHHHHHHCCCCEEEEEECCEEEECCCCEEEECCCCCCCCCHHCCCCCHHHHHHCCCHH
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVV
HHHHCHHHCCEEEEEEECCCEEEEECCCHHHHEEEEEEECCCCCCCEEECCCCCCHHHHH
EAFKLILEDKSVKGVLINIFGGIVRCDMIAEAIVAAVKEINVNVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHH
ILNESGLKLTSADGLNDAAEKIVAAVNA
HHCCCCCEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKELLAGYGLPVQGGILARNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSREEAKEVAESLIGTNLVTYQTDANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEHEECCCCE
RITFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQAREVAFQLGLKDKQINEFVK
EEEEEEECCCCCEEHHHHHCCCHHHEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHH
LMTGAYKAFVDNDFALFEVNPLAVRENGALACVDGKIGIDSNALYRLPKIAELRDKSQEN
HHHHHHHHHCCCCEEEEEECCEEEECCCCEEEECCCCCCCCCHHCCCCCHHHHHHCCCHH
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVV
HHHHCHHHCCEEEEEEECCCEEEEECCCHHHHEEEEEEECCCCCCCEEECCCCCCHHHHH
EAFKLILEDKSVKGVLINIFGGIVRCDMIAEAIVAAVKEINVNVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHH
ILNESGLKLTSADGLNDAAEKIVAAVNA
HHCCCCCEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA