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The map label for this gene is pyrF [H]

Identifier: 161869765

GI number: 161869765

Start: 792261

End: 793001

Strand: Direct

Name: pyrF [H]

Synonym: NMCC_0785

Alternate gene names: 161869765

Gene position: 792261-793001 (Clockwise)

Preceding gene: 161869764

Following gene: 161869766

Centisome position: 36.79

GC content: 56.01

Gene sequence:

>741_bases
ATGAATCCTTTAATCTCCGACTTCCAAACTCCGCAACAACGCACCCCCGTCATCGTCGCCCTTGATTTTGCCAACGAAAA
AGACACGCTCGGATTCGTCCGCAACCTTGACCCGACATTGTGTCAAATCAAAATCGGCAAAGAGCTGTTTACCGCGACGG
GACGCAGTTTGGCAGAAAGCTTAATCAATCAAGGTTTCAAACTTTTCCTCGATTTGAAATACCACGATATTCCCCACACC
GTCGCGCAAGCCTGCAAAGTCGCTGCCGACATGGGCGTTTGGATGGTCGATATGCACGCGTCGGGCGGCCGCCGTATGAT
GGAAGCCGCAGCAGAAGCCGTTGCCGGATACGGCACAAAGCCGCTCTTAATCGGCGTAACCGTGTTGACCAGCATGGAAC
AAAGCGATTTGGCGGAAATCGGTTTGAACATCGCTCCCGAAGAACAAGTCATCCGTTTGGCGAAACTGGCGCAAAGTTCG
GGCTTGGACGGCGTGGTCTGCTCCGCCCAAGAAGCCGCACCGCTGCGCCGCGAGTTGGGACAAGATTTTGTCTTGGTCAC
GCCCGGTATCCGCTTGGACGTTGCCGGCAACAACGACGACCAACGCCGCATCATGACGCCCGCCGAAGCCTTGGCGGCAG
GTTCGACTTATCTCGTGATGGGCCGCCCCGTTACCCAAGCCGCCAATCCGCTAGCCGTATTGCGCGAAGTGAACCGCGTG
GCAAACCTTGAAGCAAACTGA

Upstream 100 bases:

>100_bases
TTTGAACTAAGGCGAGACAACGCCGTACCGGTTTAAAGTTAATCCACTATACTGCGAAAAAGACGATAAAGGTCGTCTGA
AAACCCGAAACGAAAACACC

Downstream 100 bases:

>100_bases
TTTTCAGGCGGCCTTACCGGTTAAGGTCGTCTGAACAAAACACAACGGAGGCAATATGCCCGCCAAGTTTCAACAAGAAA
CCCTCAAATCCCGTTTCGCA

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MNPLISDFQTPQQRTPVIVALDFANEKDTLGFVRNLDPTLCQIKIGKELFTATGRSLAESLINQGFKLFLDLKYHDIPHT
VAQACKVAADMGVWMVDMHASGGRRMMEAAAEAVAGYGTKPLLIGVTVLTSMEQSDLAEIGLNIAPEEQVIRLAKLAQSS
GLDGVVCSAQEAAPLRRELGQDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAGSTYLVMGRPVTQAANPLAVLREVNRV
ANLEAN

Sequences:

>Translated_246_residues
MNPLISDFQTPQQRTPVIVALDFANEKDTLGFVRNLDPTLCQIKIGKELFTATGRSLAESLINQGFKLFLDLKYHDIPHT
VAQACKVAADMGVWMVDMHASGGRRMMEAAAEAVAGYGTKPLLIGVTVLTSMEQSDLAEIGLNIAPEEQVIRLAKLAQSS
GLDGVVCSAQEAAPLRRELGQDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAGSTYLVMGRPVTQAANPLAVLREVNRV
ANLEAN
>Mature_246_residues
MNPLISDFQTPQQRTPVIVALDFANEKDTLGFVRNLDPTLCQIKIGKELFTATGRSLAESLINQGFKLFLDLKYHDIPHT
VAQACKVAADMGVWMVDMHASGGRRMMEAAAEAVAGYGTKPLLIGVTVLTSMEQSDLAEIGLNIAPEEQVIRLAKLAQSS
GLDGVVCSAQEAAPLRRELGQDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAGSTYLVMGRPVTQAANPLAVLREVNRV
ANLEAN

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=225, Percent_Identity=55.1111111111111, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 26468; Mature: 26468

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLISDFQTPQQRTPVIVALDFANEKDTLGFVRNLDPTLCQIKIGKELFTATGRSLAES
CCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCEEEEEECHHHHHHCCHHHHHH
LINQGFKLFLDLKYHDIPHTVAQACKVAADMGVWMVDMHASGGRRMMEAAAEAVAGYGTK
HHHCCEEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
PLLIGVTVLTSMEQSDLAEIGLNIAPEEQVIRLAKLAQSSGLDGVVCSAQEAAPLRRELG
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCC
QDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAGSTYLVMGRPVTQAANPLAVLREVNRV
CCEEEECCCEEEEECCCCCCCCEEECHHHHHHCCCEEEEECCCHHHHCCHHHHHHHHHHH
ANLEAN
HCCCCC
>Mature Secondary Structure
MNPLISDFQTPQQRTPVIVALDFANEKDTLGFVRNLDPTLCQIKIGKELFTATGRSLAES
CCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCEEEEEECHHHHHHCCHHHHHH
LINQGFKLFLDLKYHDIPHTVAQACKVAADMGVWMVDMHASGGRRMMEAAAEAVAGYGTK
HHHCCEEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
PLLIGVTVLTSMEQSDLAEIGLNIAPEEQVIRLAKLAQSSGLDGVVCSAQEAAPLRRELG
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCC
QDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAGSTYLVMGRPVTQAANPLAVLREVNRV
CCEEEECCCEEEEECCCCCCCCEEECHHHHHHCCCEEEEECCCHHHHCCHHHHHHHHHHH
ANLEAN
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA