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The map label for this gene is mrdB [H]

Identifier: 161526280

GI number: 161526280

Start: 3398263

End: 3399411

Strand: Direct

Name: mrdB [H]

Synonym: Bmul_3111

Alternate gene names: 161526280

Gene position: 3398263-3399411 (Clockwise)

Preceding gene: 161526279

Following gene: 161526294

Centisome position: 98.54

GC content: 65.1

Gene sequence:

>1149_bases
ATGCAATTCGACAAGCGCGCCTGGCTCGACAAGATCAAGCAGATGTTCGCGGGCTTCGACCGCCCGCTCGCCCTCATCGT
GTTCCTGCTGCTGTGCGTCGGGATCGTCACGCTGTACAGCGCGAGCATCGACATGCCGGGCCGCGTCGAGGATCAGTTGC
GCAACATCCTGCTGACGTTCGTGCTGATGTGGGTGATCGCCAACATTCCGCCGACGACGCTGATGCGTTTCGCGGTCCCG
CTCTATACGTTCGGCGTCGCGCTGCTCGTCGCGGTCGCGCTGTTCGGCATGACCAAGAAGGGCGCGAAACGCTGGCTGAA
CGTCGGCGTCGTGATCCAGCCGTCCGAGATTCTGAAGATCGCGACGCCGCTGATGCTCGCGTGGTACTACCAGCGCCGCG
AAGGCGCGCTGCGCTGGTACGACTTCGTCGCCGCGTTCGGGATCCTGCTCGTGCCGGTCGGCCTGATCGCGAAGCAGCCC
GACCTCGGCACCGGTCTGCTCGTGTTCGCGGCCGGCTTCTTCGTGATCTATCTGGCCGGCCTGTCGTTCAAGCTGATCGT
GCCGGTGCTCGTCGCCGGCGTGATCGCGGTCGGCTCGATCGCCGTATTCGAGGAGCGCATCTGCCAGCCGGAAGTGCAGT
GGCCGCTGATGCACGACTATCAGAAGCACCGCGTCTGCACGCTGCTCGATCCGACCTCCGATCCGCTCGGCAAGGGCTTC
CATACGATCCAGGCGGTGATCGCGATCGGCTCCGGCGGCGTGCTCGGCAAAGGCTATCTGAAAGGCACGCAGGCGCACCT
CGAATTCATTCCGGAAAAGCACACCGACTTCATCTTCGCGGTGTTCTCCGAGGAATGGGGGCTCGTCGGCGGCCTCGTGC
TGCTCACGCTCTACATGGCGCTGATCGCGCGCGGGCTATACATCGCCGCGCAAGGCGCGACGCTGTTCGGCCGGCTGCTC
GCGGGCTCGCTGACGCTCGCGTTCTTCGTCTATGCGTTCGTGAACATCGGCATGGTCAGCGGCGTGCTGCCGGTGGTCGG
CGTGCCGCTGCCGTTCATGAGCTACGGCGGCACCGCGCTCACGACGCTCGGCATCGCGATCGGGATGATCATGAGCGTCG
GCCGCCAGCGCCGGCTGATGAAAAGCTGA

Upstream 100 bases:

>100_bases
ACGGGCAGCCGTTCGCGGCCGGCCCGCGCGACGACCACTCTCGTGCCACGGCGGCCGCGGACGCGGCAAACGCCGGCACC
GCTCATTAACGGAGAAAGGC

Downstream 100 bases:

>100_bases
GCGCTGGCGGCGCCGGCCGCCCGTGCGCGCGGCGCGCTTCTTACTGCGGCGCCGCGTGCGAATCGCCCTGCGCGCCGCTG
CCCGCGCCCGACCCTTGCGC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGALRWYDFVAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLVGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS

Sequences:

>Translated_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGALRWYDFVAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLVGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS
>Mature_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGALRWYDFVAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLVGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=382, Percent_Identity=48.6910994764398, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1786277, Length=378, Percent_Identity=30.4232804232804, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41736; Mature: 41736

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGALRWYDFVAAFGILLVPVGLIAKQPDLGTGLLVFAAGFFVIYLAG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLVGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGALRWYDFVAAFGILLVPVGLIAKQPDLGTGLLVFAAGFFVIYLAG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLVGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]