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The map label for this gene is dppA [H]

Identifier: 161526209

GI number: 161526209

Start: 3322630

End: 3324258

Strand: Reverse

Name: dppA [H]

Synonym: Bmul_3040

Alternate gene names: 161526209

Gene position: 3324258-3322630 (Counterclockwise)

Preceding gene: 161526210

Following gene: 161526208

Centisome position: 96.4

GC content: 62.68

Gene sequence:

>1629_bases
ATGGAACACAACCGTCTGTTGCACACCCTGCGTGTTACCGCCATTGCAGGCGTGGCAGCGGCATCGCTCGGCGTCGCGGG
CTCTGCATTCGCACAGATCCCGAACAAGACGCTCGTCTACTGCTCAGAAGGCAGCCCGGCGGGCTTCGATTCCGCGCAAT
ACACGACCGGCGTCGATTTCACGGCCGCCACGTTCACCGTCTACAACCGCCTCGTCGAATTCGTGCGCGGCGGCACGAAG
GTCGAGCCCGGCCTCGCCGAGAAGTGGGACGTGTCGTCCGACGGCAAGGTCTATACGTTCCACCTGCGCCACGGCGTGAA
GTTCCACACGACCGACTTCTTCAAGCCGACGCGTGAATTCAACGCGGACGACGTCGTGTTCACGTTCGAGCGCATGCTCG
ATCCGAACAACGCGTTCCGCAAGGCGTATCCGGTGTCGTTCCCGTACTTCACCGACATGGGCCTCGACAAGCTGATCACG
AAGGTCGAGAAGGTCGATCCGTACACGGTGAAGTTCACGCTCGCCGAACCGAACGCGCCGTTCATCCAAAACATGGCGAT
GGAATTCGCGTCGATCCTGTCGGCCGAATACGCGGATCAGCTGATGAAGGCCGGCAAGGCCGCCGACATCAACCAGAAGC
CGGTCGGCACGGGCCCGTTCATCTTCCGCAGCTACACGAAGGACGCGACGATCCGTTTCGACGGCAATCCGGATTACTGG
AAGAAGGGCGAAGTGAAGCTGTCGAAGCTGATCTTCTCGATCACGCCCGATCCGGGCGTGCGCGTGCAGAAGATCAAGCG
CAACGAATGCCAGGTGATGAGCTATCCGCGCCCGGCCGACATCGCGACGCTGAAGGCCGACTCGAACATCGACATGCCGT
CGCAGCCGGGCTTCAACCTCGGCTACCTCGCGTACAACGTCGAGCACAAGCCGGTCGACAAGCTCGACGTGCGCCAGGCG
CTCGACATGGCGATCAACAAGAAGGCGATTCTCGAATCGGTCTATCAGGGTGCGGGCCAGGCCGCGAATGCGCCGATGCC
GCCGACGCAGTGGTCCTACGACAAGAACCTGAAGATGCCCGCCTACGACACCGCGAAGGCGAAGGCGCTGCTCGCGAAGG
CCGGTTATCCGAACGGTTTCGAGATCACGCTGTGGGCGATGCCGGTGCAGCGCGCATACAACCCGAACGCACGTCTGATG
GCCGAGATGATCCAGGCCGACTGGGCGAAGATCGGCGTGAAGGCGAAGATCGTCACGTACGAGTGGGGCGAGTACATCAA
GCGCGCGCACGGCGGCGAGCAGGACACGATGCTGATCGGCTGGACCGGCGACAACGGCGACCCCGACAACTGGCTCGGCA
CGCTGCTCGGCTGCGAGGCGATCAAGGGCAACAACTTCTCGCACTGGTGCTACAAGCCGTTCGACGACCTGATCCAGAAG
GGCCGCACGACGACGGGCCAGGACGCGCGCACGAAGCTCTACACGCAGGCGCAGCAGATCTTCGCGCAACAGCTGCCGTT
CTCGCCGATCGCGAACTCGACGGTGTACCAGCCGGTGCGCAAGAACGTCGTCGACATGCGCATCGAGCCGCTCGGCTACG
CACGCTTCGATGGTGTGAGCGTGAAGTAA

Upstream 100 bases:

>100_bases
GGTTTTTTCTCCAGCTTGTTGCAAAATCGCTTGCTCAAGTAATATCCGCGTACGCCGGCCCCGGGAGGGACCGGTTCCGA
TCTGGAGACCTGGAGGAAAC

Downstream 100 bases:

>100_bases
CGCAGCAGGCGTAAGCTGTCACGAAGACCGAGACCTACCCATCCGGCGGCGGGGGGCCACGAGCTCCCCGTCGCCGGTCG
CACATTTCCCACAAGAAAAG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MEHNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQYTTGVDFTAATFTVYNRLVEFVRGGTK
VEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVVFTFERMLDPNNAFRKAYPVSFPYFTDMGLDKLIT
KVEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYADQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGEVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNIDMPSQPGFNLGYLAYNVEHKPVDKLDVRQA
LDMAINKKAILESVYQGAGQAANAPMPPTQWSYDKNLKMPAYDTAKAKALLAKAGYPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHGGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDDLIQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK

Sequences:

>Translated_542_residues
MEHNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQYTTGVDFTAATFTVYNRLVEFVRGGTK
VEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVVFTFERMLDPNNAFRKAYPVSFPYFTDMGLDKLIT
KVEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYADQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGEVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNIDMPSQPGFNLGYLAYNVEHKPVDKLDVRQA
LDMAINKKAILESVYQGAGQAANAPMPPTQWSYDKNLKMPAYDTAKAKALLAKAGYPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHGGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDDLIQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK
>Mature_542_residues
MEHNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQYTTGVDFTAATFTVYNRLVEFVRGGTK
VEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVVFTFERMLDPNNAFRKAYPVSFPYFTDMGLDKLIT
KVEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYADQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGEVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNIDMPSQPGFNLGYLAYNVEHKPVDKLDVRQA
LDMAINKKAILESVYQGAGQAANAPMPPTQWSYDKNLKMPAYDTAKAKALLAKAGYPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHGGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDDLIQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=519, Percent_Identity=55.4913294797688, Blast_Score=600, Evalue=1e-172,
Organism=Escherichia coli, GI1787551, Length=533, Percent_Identity=35.2720450281426, Blast_Score=338, Evalue=4e-94,
Organism=Escherichia coli, GI1787052, Length=459, Percent_Identity=30.0653594771242, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1787762, Length=498, Percent_Identity=25.5020080321285, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789887, Length=468, Percent_Identity=27.3504273504274, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787495, Length=452, Percent_Identity=24.5575221238938, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1789397, Length=509, Percent_Identity=23.9685658153242, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081878, Length=566, Percent_Identity=24.2049469964664, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60412; Mature: 60412

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQYTTGVDF
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCH
TAATFTVYNRLVEFVRGGTKVEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHCC
NADDVVFTFERMLDPNNAFRKAYPVSFPYFTDMGLDKLITKVEKVDPYTVKFTLAEPNAP
CCCCEEEEHHHHCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNMAMEFASILSAEYADQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCC
KKGEVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNIDMPSQPGFNL
CCCCEEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVEHKPVDKLDVRQALDMAINKKAILESVYQGAGQAANAPMPPTQWSYDKNLKMP
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
AYDTAKAKALLAKAGYPNGFEITLWAMPVQRAYNPNARLMAEMIQADWAKIGVKAKIVTY
CCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHGGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDDLIQK
HHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHC
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCEECCCCC
VK
CC
>Mature Secondary Structure
MEHNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQYTTGVDF
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCH
TAATFTVYNRLVEFVRGGTKVEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHCC
NADDVVFTFERMLDPNNAFRKAYPVSFPYFTDMGLDKLITKVEKVDPYTVKFTLAEPNAP
CCCCEEEEHHHHCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNMAMEFASILSAEYADQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCC
KKGEVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNIDMPSQPGFNL
CCCCEEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVEHKPVDKLDVRQALDMAINKKAILESVYQGAGQAANAPMPPTQWSYDKNLKMP
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
AYDTAKAKALLAKAGYPNGFEITLWAMPVQRAYNPNARLMAEMIQADWAKIGVKAKIVTY
CCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHGGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDDLIQK
HHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHC
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCEECCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]