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The map label for this gene is ruvC [H]

Identifier: 161525863

GI number: 161525863

Start: 2942559

End: 2943101

Strand: Direct

Name: ruvC [H]

Synonym: Bmul_2694

Alternate gene names: 161525863

Gene position: 2942559-2943101 (Clockwise)

Preceding gene: 161525862

Following gene: 161525864

Centisome position: 85.33

GC content: 70.35

Gene sequence:

>543_bases
ATGCGAATTCTCGGCATCGACCCCGGCCTGCGCGTTACCGGCTTCGGCGTCATCGACGTTAGCGGCCATCAGCTCGCCTA
TGTCGCGAGCGGCGTGATCCGCACGCCGACGGCCGATCTGGCCACGCGCCTCGGCACGATCTTCGCGGGCGTCTCGACGC
TCGTACGCGAACACGCGCCGGACCAGGCCGCGATCGAAAAAGTGTTCGTCAACGTGAACCCACAGTCGACGCTGCTGCTC
GGCCAGGCGCGCGGCGCCGCGATCTGCGGGCTCGTGTCGGGCGGACTGCCCGTCGCCGAATACACCGCGCTGCAGCTGAA
GCAGGCGATCGTCGGCTACGGCCGCGCGACGAAGGCGCAGATGCAGGAGATGGTCACGCGGCTGCTGAGCCTGAGCGGCC
AGCCCGGCAGCGATGCGGCCGACGCGCTCGGCATCGCGATCTGCCATGCGCACGGCGGCAATACGTTGAGCACGCTCGGC
GGTCTCGCGCCGGCGCTCGCGCAGAAAGGCCTGCGCTTGCGCCGCGGCCGGCTCGTCGGCTGA

Upstream 100 bases:

>100_bases
CCTCGCGCGAACGTGGGTTCCGCATCGCTGCGCCGCGTGCGGCGACGGCGCCCTGCCCCTTTCGTTGTAGTATCGCTGCA
TCACGCAACTCCCTCTTCAC

Downstream 100 bases:

>100_bases
GCGGCACGGAGCGCACCGCCGGCATGCGCCGGCGAACGGCCGGCCGCCCGCAGCCGGCGCGACCGCTCGGCACCCGGCGT
CGCGCGTTCGCGCCGCTGCC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIRTPTADLATRLGTIFAGVSTLVREHAPDQAAIEKVFVNVNPQSTLLL
GQARGAAICGLVSGGLPVAEYTALQLKQAIVGYGRATKAQMQEMVTRLLSLSGQPGSDAADALGIAICHAHGGNTLSTLG
GLAPALAQKGLRLRRGRLVG

Sequences:

>Translated_180_residues
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIRTPTADLATRLGTIFAGVSTLVREHAPDQAAIEKVFVNVNPQSTLLL
GQARGAAICGLVSGGLPVAEYTALQLKQAIVGYGRATKAQMQEMVTRLLSLSGQPGSDAADALGIAICHAHGGNTLSTLG
GLAPALAQKGLRLRRGRLVG
>Mature_180_residues
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIRTPTADLATRLGTIFAGVSTLVREHAPDQAAIEKVFVNVNPQSTLLL
GQARGAAICGLVSGGLPVAEYTALQLKQAIVGYGRATKAQMQEMVTRLLSLSGQPGSDAADALGIAICHAHGGNTLSTLG
GLAPALAQKGLRLRRGRLVG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=176, Percent_Identity=51.1363636363636, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18459; Mature: 18459

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIRTPTADLATRLGTIFAGVSTLVREHAP
CEEECCCCCCEEEEEEEEECCCCEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DQAAIEKVFVNVNPQSTLLLGQARGAAICGLVSGGLPVAEYTALQLKQAIVGYGRATKAQ
CHHHHHHHEEECCCCCEEEEECCCCCEEEEHHCCCCCHHHHHHHHHHHHHHCCCCCHHHH
MQEMVTRLLSLSGQPGSDAADALGIAICHAHGGNTLSTLGGLAPALAQKGLRLRRGRLVG
HHHHHHHHHHCCCCCCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCC
>Mature Secondary Structure
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIRTPTADLATRLGTIFAGVSTLVREHAP
CEEECCCCCCEEEEEEEEECCCCEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DQAAIEKVFVNVNPQSTLLLGQARGAAICGLVSGGLPVAEYTALQLKQAIVGYGRATKAQ
CHHHHHHHEEECCCCCEEEEECCCCCEEEEHHCCCCCHHHHHHHHHHHHHHCCCCCHHHH
MQEMVTRLLSLSGQPGSDAADALGIAICHAHGGNTLSTLGGLAPALAQKGLRLRRGRLVG
HHHHHHHHHHCCCCCCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA