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The map label for this gene is ruvA [H]

Identifier: 161525864

GI number: 161525864

Start: 2943291

End: 2943872

Strand: Direct

Name: ruvA [H]

Synonym: Bmul_2695

Alternate gene names: 161525864

Gene position: 2943291-2943872 (Clockwise)

Preceding gene: 161525863

Following gene: 161525865

Centisome position: 85.35

GC content: 67.35

Gene sequence:

>582_bases
ATGATCGGTCGCATCGCCGGCATCCTGCTCGAAAAGAATCCGCCTCACCTGCTCGTCGACTGCAACGGCGTCGGCTACGA
AATCGACGTGCCGATGAGCACCTTCTACAACCTGCCGCAGACGGGCGAGCGCGTCGTCCTGCTCACGCAGCAGATCGTGC
GCGAGGACGCGCACCTGCTGTACGGCTTTCTCACACCGCAGGAGCGCACGACCTTCCGCGAGCTGCTGAAGATCACCGGC
ATCGGCGCGCGCATGGCGCTCGCCGTGCTGTCCGGCATGAGCGTGCAGGAGCTCGCGCAGGCCGTGACGATGCAGGACGC
CGCGCGCCTCACGCGCCTGCCCGGCATCGGCAAGAAGACCGCGGAGCGCCTGCTGCTCGAACTGAAAGGCAAGCTCGGCG
CCGACCTCGGTGCACTCGCCGGCGCCGCGTCGGCGTCCGACCACGCGACCGACATCCTCAACGCGCTGCTCGCGCTCGGC
TATTCCGAAAAGGAAGGCCTCGCGGCGATCAAGAACGTGCCGGCCGGCACCGGCGTGTCTGAAGGCATCAAGCTCGCGCT
GAAGGCGCTCTCCAAGGCGTAA

Upstream 100 bases:

>100_bases
GCGCCGCTGCCGCGCCGTGGCGCCGCCCGCCGCGCCGAACCATCGGCTTTGCGCCGCACGTGCGCTACACTCGCGCTTTC
TTCCTCGCATCCCGCCATCC

Downstream 100 bases:

>100_bases
CGGCCCGTCGCATCCAGTGTCGCGCGGCGTCGGCGCGCGCGACAGTCGGCCGTTCGGCCAGGTTGGCCGCGCCACGCCGC
GCGGTACAATGGCCGCATGA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLLYGFLTPQERTTFRELLKITG
IGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGALAGAASASDHATDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKA

Sequences:

>Translated_193_residues
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLLYGFLTPQERTTFRELLKITG
IGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGALAGAASASDHATDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKA
>Mature_193_residues
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLLYGFLTPQERTTFRELLKITG
IGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGALAGAASASDHATDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=44.7761194029851, Blast_Score=173, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20385; Mature: 20385

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLL
CCCHHEEEEECCCCCEEEEECCCCCEEEECCHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
YGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKT
HEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGALAGAASASDHATDILNALLALGYSEKEGLAAIKNVPAGTGVS
HHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
EGIKLALKALSKA
HHHHHHHHHHHCC
>Mature Secondary Structure
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLL
CCCHHEEEEECCCCCEEEEECCCCCEEEECCHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
YGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKT
HEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGALAGAASASDHATDILNALLALGYSEKEGLAAIKNVPAGTGVS
HHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
EGIKLALKALSKA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA