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The map label for this gene is cobL [H]

Identifier: 161524740

GI number: 161524740

Start: 1717194

End: 1718432

Strand: Reverse

Name: cobL [H]

Synonym: Bmul_1567

Alternate gene names: 161524740

Gene position: 1718432-1717194 (Counterclockwise)

Preceding gene: 161524745

Following gene: 161524739

Centisome position: 49.83

GC content: 75.38

Gene sequence:

>1239_bases
ATGACGGCATGGCTGACGGTGGTGGGCATCGGCGACGACGGCTTCGCGGGGCTCGGCCGCGCCGCACGCCGCGCGCTGCT
CGACGCGACGCTCGTCGTCGGCGCGAAGCGGCATCTCGACATGTTGCCGTCGCGACTGCCGGCCGCGCGCGAAGCGTGGC
CGTCGCCGTTCGACCTGTCGGGCGTGCTCGCGCGGCGCGGCTCGCCCGTCTGCGTGCTCGCGAGCGGCGACCCGATGCTG
TTCGGCGTCGGCGCGACGCTCGCACGCCGGCTCGGCGGCGACGAATGGCGCGTACTGCCGGCGCCGTCGTCGCTGTCGCT
CGCGGCCGCGCGGCTCGGCTGGGCGCTGCAGGACGTCGGCGCCGTGTCGCTGGTCGGCCGCCCGCTCGCGACGCTCGCGC
GCCATCTGCTGCCGGGCCGGCGCCTGTTCGTGCTGAGCGCGGACGGCCGCACGCCGGCCGCCGTCGCGGCCGAGCTCGTC
GCGCGCGGGTTCGGCCCGACGCGCATCAGCGTGTTCGAACACCTCGGCGGCCCGCTCGAGCGGCGCATCGACGGTCTCGC
GCAAGACTGGAACGTCGAAGAGACGGCCGCGCTCAATCTCGTCGCGCTCGACTGCGAAGCCGGCCCCGACGCGCCGCGCC
GCGCACTGACGCCCGGGCTGCCCGACGACGCCTATCGCCACGACGGCCAACTGACGAAGCGCGACATGCGCGCGCTGACG
CTCGCGCGCCTCGCGCCGGCGCCCGGCGAACTGCTGTGGGACGTCGGTGCGGGCAGCGGCTCGATCGGCATCGAATGGAT
GCGCGCGCATCCGTCGTGTCAAGCGATCGCGATCGAATCGCATGCGGAGCGGCAGCGCTTCATCGAACACAACCGCGACG
CGCTCGGCGTGCCGGGCCTGCAGCTCGTCGCCGGCCGCGCGCCCGATGCGCTGGCCGGACTGGCCGCGCCCGACGCGATC
TTCATCGGCGGCGGCGCGACGACGCCCGGCGTGCTCGACGCATGCTGGGCCGCGCTGAAACCGGGTGGCCGGCTCGTCGC
GAACGCGGTCACGCTGCAGGGCGACGTCGCGCTCGCCGGATGGCGCGACGCGCACGGCGGCACGCTCACGCGCGTGTCGA
TCGCGCATGCGGAACCGCTCGGCCGCTTCGACACCTGGCGACAGGCGCTGCCCGTCACGCTGTACGACGTGCGCAAACCC
GATACGACCGCCGCGCCGTGCGCCGCGGAGTGCCGCTGA

Upstream 100 bases:

>100_bases
TGCCTGCCGGTGAAACGCGGAGTCGAACACGGTACTATCCCGTTTTTGGCGATGCAGACCGGTACGCGGCGGCAACAGGA
CGAACGATGGGGAAGGGTGC

Downstream 100 bases:

>100_bases
TGCGCGACGAGACGCCCGAACGGCCCGCGCCGCTGCGCTTCGGCTATACGACCGGCAGCTGTGCGACCGCGACGTCGCTC
GCGGCGGCGCGCCTGCTGCT

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTAWLTVVGIGDDGFAGLGRAARRALLDATLVVGAKRHLDMLPSRLPAAREAWPSPFDLSGVLARRGSPVCVLASGDPML
FGVGATLARRLGGDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELV
ARGFGPTRISVFEHLGGPLERRIDGLAQDWNVEETAALNLVALDCEAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
LARLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIESHAERQRFIEHNRDALGVPGLQLVAGRAPDALAGLAAPDAI
FIGGGATTPGVLDACWAALKPGGRLVANAVTLQGDVALAGWRDAHGGTLTRVSIAHAEPLGRFDTWRQALPVTLYDVRKP
DTTAAPCAAECR

Sequences:

>Translated_412_residues
MTAWLTVVGIGDDGFAGLGRAARRALLDATLVVGAKRHLDMLPSRLPAAREAWPSPFDLSGVLARRGSPVCVLASGDPML
FGVGATLARRLGGDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELV
ARGFGPTRISVFEHLGGPLERRIDGLAQDWNVEETAALNLVALDCEAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
LARLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIESHAERQRFIEHNRDALGVPGLQLVAGRAPDALAGLAAPDAI
FIGGGATTPGVLDACWAALKPGGRLVANAVTLQGDVALAGWRDAHGGTLTRVSIAHAEPLGRFDTWRQALPVTLYDVRKP
DTTAAPCAAECR
>Mature_411_residues
TAWLTVVGIGDDGFAGLGRAARRALLDATLVVGAKRHLDMLPSRLPAAREAWPSPFDLSGVLARRGSPVCVLASGDPMLF
GVGATLARRLGGDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELVA
RGFGPTRISVFEHLGGPLERRIDGLAQDWNVEETAALNLVALDCEAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALTL
ARLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIESHAERQRFIEHNRDALGVPGLQLVAGRAPDALAGLAAPDAIF
IGGGATTPGVLDACWAALKPGGRLVANAVTLQGDVALAGWRDAHGGTLTRVSIAHAEPLGRFDTWRQALPVTLYDVRKPD
TTAAPCAAECR

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43175; Mature: 43044

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00047 HISTONE_H4 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWLTVVGIGDDGFAGLGRAARRALLDATLVVGAKRHLDMLPSRLPAAREAWPSPFDLS
CCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCCCCH
GVLARRGSPVCVLASGDPMLFGVGATLARRLGGDEWRVLPAPSSLSLAAARLGWALQDVG
HHHHCCCCCEEEEECCCCEEEEHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
AVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELVARGFGPTRISVFEHLGGPLE
HHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RRIDGLAQDWNVEETAALNLVALDCEAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
HHHHHHHHCCCCCHHHEEEEEEEECCCCCCCCHHHCCCCCCCHHHHCCCCHHHHHHHHHH
LARLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIESHAERQRFIEHNRDALGVPGL
HHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCCH
QLVAGRAPDALAGLAAPDAIFIGGGATTPGVLDACWAALKPGGRLVANAVTLQGDVALAG
HEEECCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCEEEEC
WRDAHGGTLTRVSIAHAEPLGRFDTWRQALPVTLYDVRKPDTTAAPCAAECR
CCCCCCCEEEEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAWLTVVGIGDDGFAGLGRAARRALLDATLVVGAKRHLDMLPSRLPAAREAWPSPFDLS
CEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCCCCH
GVLARRGSPVCVLASGDPMLFGVGATLARRLGGDEWRVLPAPSSLSLAAARLGWALQDVG
HHHHCCCCCEEEEECCCCEEEEHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
AVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELVARGFGPTRISVFEHLGGPLE
HHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RRIDGLAQDWNVEETAALNLVALDCEAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
HHHHHHHHCCCCCHHHEEEEEEEECCCCCCCCHHHCCCCCCCHHHHCCCCHHHHHHHHHH
LARLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIESHAERQRFIEHNRDALGVPGL
HHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCCH
QLVAGRAPDALAGLAAPDAIFIGGGATTPGVLDACWAALKPGGRLVANAVTLQGDVALAG
HEEECCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCEEEEC
WRDAHGGTLTRVSIAHAEPLGRFDTWRQALPVTLYDVRKPDTTAAPCAAECR
CCCCCCCEEEEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]