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The map label for this gene is kdgR [H]

Identifier: 161524745

GI number: 161524745

Start: 1723515

End: 1724258

Strand: Reverse

Name: kdgR [H]

Synonym: Bmul_1572

Alternate gene names: 161524745

Gene position: 1724258-1723515 (Counterclockwise)

Preceding gene: 161524746

Following gene: 161524740

Centisome position: 50.0

GC content: 68.68

Gene sequence:

>744_bases
ATGGACGTCAAACTCGTTGCCCGCACGCTCGACCTGTTCGAACTGTTCGCCGCCGAACGGCGGCCGCTGCCGCTCACCGA
ACTCGCGCGCCTGCTGAACGTGCCGGCGTCGAGCTGTCTCGCGATGGCGCGCACGCTCGTAAGCCGCGGCTATCTGTACG
AAGTGCGCAAGCGCGGCGGCTACTATCCGACGCGGCGTCTACAGACGATCGCGGCCGCGATCGACGCGACCGATCCTGTC
GTCGACATCGTCCATCCGTATCTCGTCGCACTGCGCGACGCGAGCCGCGAAACGGCCGTGCTCGGCAAGATCCAGCGCGC
GTCGATCGCCTATCTCGACGTCGTCGAATCGGAGCAGGCGATCCGCTATACGAGCCAGCCCGGCGAATTGCGTCCGCTGC
ATGCGAACTCGATCGGCAAGGCGATCTTCGCGGAACTGGCCGGCGATGCGCAGCAGGCGCTCGGCGAAGCGCTGACGTTC
GAGCGCTTCACCGCGGCGACCGTCGCCGATCTGCCGGCGCTCGTCGCGCAGACGGCGCGCTTTCGCAAGCGCGGCTGGGC
CGAAAACTTCGGCGAGAGTGCGCCGGAGCTGTCGGCGATCGCGGTCGCGCTACCGCTCGACGGCGACTGGTACGGGCTGT
CGATCGTCGGGCCGACGGAACGGATTCGCCAGCATCGCGACGCGCACGCGGCGCTGCTCGTCGACGCGAAGGCGCGGCTG
CTCGCCGATTACGCGCGCGCGTAA

Upstream 100 bases:

>100_bases
CTGTGCTACATCGCGGAGAAGGTGCTCGGGCTGCCGAAATCGTACTGATGCGCGGCGGCCGTCCGGCGCGCGTTTTCCCG
TTCCGTTTCAAGCGCTCGTC

Downstream 100 bases:

>100_bases
CGCGCGGGCGTGCCGCTGCCGCGCACGCCCCGGTGCGCGGCGCGTCGCTCATCGATACCAGCGCGGCGTATAGACCCACT
CGCGTCCGGCGCCGATCGCA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGGYYPTRRLQTIAAAIDATDPV
VDIVHPYLVALRDASRETAVLGKIQRASIAYLDVVESEQAIRYTSQPGELRPLHANSIGKAIFAELAGDAQQALGEALTF
ERFTAATVADLPALVAQTARFRKRGWAENFGESAPELSAIAVALPLDGDWYGLSIVGPTERIRQHRDAHAALLVDAKARL
LADYARA

Sequences:

>Translated_247_residues
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGGYYPTRRLQTIAAAIDATDPV
VDIVHPYLVALRDASRETAVLGKIQRASIAYLDVVESEQAIRYTSQPGELRPLHANSIGKAIFAELAGDAQQALGEALTF
ERFTAATVADLPALVAQTARFRKRGWAENFGESAPELSAIAVALPLDGDWYGLSIVGPTERIRQHRDAHAALLVDAKARL
LADYARA
>Mature_247_residues
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGGYYPTRRLQTIAAAIDATDPV
VDIVHPYLVALRDASRETAVLGKIQRASIAYLDVVESEQAIRYTSQPGELRPLHANSIGKAIFAELAGDAQQALGEALTF
ERFTAATVADLPALVAQTARFRKRGWAENFGESAPELSAIAVALPLDGDWYGLSIVGPTERIRQHRDAHAALLVDAKARL
LADYARA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=247, Percent_Identity=25.9109311740891, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786468, Length=200, Percent_Identity=25.5, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082359, Length=231, Percent_Identity=27.7056277056277, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788581, Length=199, Percent_Identity=25.6281407035176, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27023; Mature: 27023

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGG
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCC
YYPTRRLQTIAAAIDATDPVVDIVHPYLVALRDASRETAVLGKIQRASIAYLDVVESEQA
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHH
IRYTSQPGELRPLHANSIGKAIFAELAGDAQQALGEALTFERFTAATVADLPALVAQTAR
HEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRKRGWAENFGESAPELSAIAVALPLDGDWYGLSIVGPTERIRQHRDAHAALLVDAKARL
HHHCCCHHHHCCCCCCCEEEEEEEECCCCEEEEEEECHHHHHHHHHCHHHEEEHHHHHHH
LADYARA
HHHHHCC
>Mature Secondary Structure
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGG
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCC
YYPTRRLQTIAAAIDATDPVVDIVHPYLVALRDASRETAVLGKIQRASIAYLDVVESEQA
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHH
IRYTSQPGELRPLHANSIGKAIFAELAGDAQQALGEALTFERFTAATVADLPALVAQTAR
HEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRKRGWAENFGESAPELSAIAVALPLDGDWYGLSIVGPTERIRQHRDAHAALLVDAKARL
HHHCCCHHHHCCCCCCCEEEEEEEECCCCEEEEEEECHHHHHHHHHCHHHEEEHHHHHHH
LADYARA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]