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The map label for this gene is dinB [H]

Identifier: 161524303

GI number: 161524303

Start: 1239360

End: 1240649

Strand: Direct

Name: dinB [H]

Synonym: Bmul_1128

Alternate gene names: 161524303

Gene position: 1239360-1240649 (Clockwise)

Preceding gene: 161524300

Following gene: 161524308

Centisome position: 35.94

GC content: 68.68

Gene sequence:

>1290_bases
GTGCGCGGCGGTACGCTTCGCGTCAAGCCGGCCGGTACGGCGCAGTGCGGGGCGGCGGCCCGCGGCAGGGCAGCGTACGA
CCGCGGTCCGCGCCTGCCTCACGCGGCGGTTGAAACGCCCACTGTGTTTTTGTACAGTATCGGCACCGTGAATCCGTCCG
CCATTCCGTCTTCCGATCCGCGCGAGCCGCCGCCCGACGGCGACGCACCGCCGCGCGTGCGCAAGATCATCCACTGCGAT
TGCGACTGCTTTTACGCATCGGTCGAGATGCGCGACGATCCGTCGTTGCGCAATCGTCCGCTCGCGGTCGGCGGCCGGCC
CGACCAGCGCGGCGTGATCGCGACGTGCAATTACGAGGCGCGGCGCTATGGCGTGCACTCGGCGATGTCGTCGGCGCTGG
CGATGCGCAAGTGTCCGGATCTGCTGATCCTGCCGAGCGCGATGGACAAGTACCGCACCGCATCGCGGCAGATCATGGCG
ATCTACCGCGACTACACGGCCGACGTCGAACCGCTGTCGCTCGACGAAGCCTATCTCGACGTGAGTCGCTCCGAGCGTTG
TCAGGGCAGCGCGACGCTGATCGCGCGCGAGATCCGGCAGCGCGTGTACGAGACGGTCGGCGTGACGGTGTCGGCCGGCG
TCGCACCGAACAAGTTCATCGCGAAGATCGCCTCCGACTGGAACAAGCCCGACGGCCTGTTCGTCGTGCGGCCGCACGAA
GTCGACGCCTTCGTCGCCGCGCTGCCGGTGCGCAAGCTGCACGGCGTCGGCAAGGTCACGGCCACGCGGCTCGACCGGCT
CGGAATCCAGACCTGCGCGCAGCTGCGGACCTGGTCGCTGATCGATCTGCATCGCGAGTTCGGCGCATTCGGCCGGCGGC
TGTACGAGCTCGCGCGCGGGATCGACGAACGGCCGGTGCAGGCTGATCAGGAGCGCAAGTCGGTCAGCGTCGAGACGACT
TACGTGACCGATCTGACCACCCTCGAGCAGTGCGCGGACGAGATCCGCCGGCTCGTCGTGCAGCTCGATGCGCGAATCGC
CCGCGCAGGCGCCGCACGCGCGATCCGCAAGCTGTACGTGAAGATCCGCTTCGCGGATTTTCAGCGTACGACGGTCGAAT
GCGTGGCCGACGCCACGAATGCCGACACGGCCGTCGCGCTGCTCGCGAAAGGGCTGCTGCGGCGCGCGCAGGCGGTGCGG
CTGCTCGGCGTCGGCGTGCGCATCGACGAAAACACGCCCGAGCGCCACGGGCAGTTCTCGCTGTTCGACGACGACTCGCG
CGCGCAATGA

Upstream 100 bases:

>100_bases
CGGCCGACGATTCCCAGCTCATTCCGCCGATCAGTCCGATCGTCTTCATCCGTTGCCCTTTCGTTCGTATGGTCGCCGTC
GAGTATAGGGGCCGGTGCGC

Downstream 100 bases:

>100_bases
GCGCGCAATGAAAAAGGCACCGCCGAAGCGGTGCCTGTGCGGCGGCGACGCGGCGCAGCCCGTCAGTGTGCGGGCGCGGC
CATCCCGTTATGACGCAGCA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRGGTLRVKPAGTAQCGAAARGRAAYDRGPRLPHAAVETPTVFLYSIGTVNPSAIPSSDPREPPPDGDAPPRVRKIIHCD
CDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPSAMDKYRTASRQIMA
IYRDYTADVEPLSLDEAYLDVSRSERCQGSATLIAREIRQRVYETVGVTVSAGVAPNKFIAKIASDWNKPDGLFVVRPHE
VDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRTWSLIDLHREFGAFGRRLYELARGIDERPVQADQERKSVSVETT
YVTDLTTLEQCADEIRRLVVQLDARIARAGAARAIRKLYVKIRFADFQRTTVECVADATNADTAVALLAKGLLRRAQAVR
LLGVGVRIDENTPERHGQFSLFDDDSRAQ

Sequences:

>Translated_429_residues
MRGGTLRVKPAGTAQCGAAARGRAAYDRGPRLPHAAVETPTVFLYSIGTVNPSAIPSSDPREPPPDGDAPPRVRKIIHCD
CDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPSAMDKYRTASRQIMA
IYRDYTADVEPLSLDEAYLDVSRSERCQGSATLIAREIRQRVYETVGVTVSAGVAPNKFIAKIASDWNKPDGLFVVRPHE
VDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRTWSLIDLHREFGAFGRRLYELARGIDERPVQADQERKSVSVETT
YVTDLTTLEQCADEIRRLVVQLDARIARAGAARAIRKLYVKIRFADFQRTTVECVADATNADTAVALLAKGLLRRAQAVR
LLGVGVRIDENTPERHGQFSLFDDDSRAQ
>Mature_429_residues
MRGGTLRVKPAGTAQCGAAARGRAAYDRGPRLPHAAVETPTVFLYSIGTVNPSAIPSSDPREPPPDGDAPPRVRKIIHCD
CDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPSAMDKYRTASRQIMA
IYRDYTADVEPLSLDEAYLDVSRSERCQGSATLIAREIRQRVYETVGVTVSAGVAPNKFIAKIASDWNKPDGLFVVRPHE
VDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRTWSLIDLHREFGAFGRRLYELARGIDERPVQADQERKSVSVETT
YVTDLTTLEQCADEIRRLVVQLDARIARAGAARAIRKLYVKIRFADFQRTTVECVADATNADTAVALLAKGLLRRAQAVR
LLGVGVRIDENTPERHGQFSLFDDDSRAQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=407, Percent_Identity=26.7813267813268, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI7706681, Length=408, Percent_Identity=26.7156862745098, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI154350220, Length=323, Percent_Identity=30.030959752322, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI5729982, Length=366, Percent_Identity=28.6885245901639, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=46.2962962962963, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1786425, Length=346, Percent_Identity=47.9768786127168, Blast_Score=321, Evalue=4e-89,
Organism=Escherichia coli, GI1787432, Length=232, Percent_Identity=28.448275862069, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=428, Percent_Identity=28.7383177570093, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17537959, Length=261, Percent_Identity=31.4176245210728, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193205702, Length=373, Percent_Identity=26.5415549597855, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI115534089, Length=122, Percent_Identity=39.344262295082, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=28.6407766990291, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19923006, Length=339, Percent_Identity=26.5486725663717, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355641, Length=290, Percent_Identity=29.3103448275862, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24644984, Length=290, Percent_Identity=29.3103448275862, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 47317; Mature: 47317

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGGTLRVKPAGTAQCGAAARGRAAYDRGPRLPHAAVETPTVFLYSIGTVNPSAIPSSDP
CCCCEEEECCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
REPPPDGDAPPRVRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEA
CCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCHH
RRYGVHSAMSSALAMRKCPDLLILPSAMDKYRTASRQIMAIYRDYTADVEPLSLDEAYLD
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
VSRSERCQGSATLIAREIRQRVYETVGVTVSAGVAPNKFIAKIASDWNKPDGLFVVRPHE
CCHHHCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCCCCEEEECCCC
VDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRTWSLIDLHREFGAFGRRLYELARG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDERPVQADQERKSVSVETTYVTDLTTLEQCADEIRRLVVQLDARIARAGAARAIRKLYV
CCCCCCCCCHHHHCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIRFADFQRTTVECVADATNADTAVALLAKGLLRRAQAVRLLGVGVRIDENTPERHGQFS
EEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEE
LFDDDSRAQ
EECCCCCCC
>Mature Secondary Structure
MRGGTLRVKPAGTAQCGAAARGRAAYDRGPRLPHAAVETPTVFLYSIGTVNPSAIPSSDP
CCCCEEEECCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
REPPPDGDAPPRVRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEA
CCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCHH
RRYGVHSAMSSALAMRKCPDLLILPSAMDKYRTASRQIMAIYRDYTADVEPLSLDEAYLD
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
VSRSERCQGSATLIAREIRQRVYETVGVTVSAGVAPNKFIAKIASDWNKPDGLFVVRPHE
CCHHHCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCCCCEEEECCCC
VDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRTWSLIDLHREFGAFGRRLYELARG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDERPVQADQERKSVSVETTYVTDLTTLEQCADEIRRLVVQLDARIARAGAARAIRKLYV
CCCCCCCCCHHHHCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIRFADFQRTTVECVADATNADTAVALLAKGLLRRAQAVRLLGVGVRIDENTPERHGQFS
EEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEE
LFDDDSRAQ
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]