Click here to switch to the map view.

The map label for this gene is aceE [H]

Identifier: 161524308

GI number: 161524308

Start: 1247547

End: 1250243

Strand: Direct

Name: aceE [H]

Synonym: Bmul_1133

Alternate gene names: 161524308

Gene position: 1247547-1250243 (Clockwise)

Preceding gene: 161524303

Following gene: 161524309

Centisome position: 36.18

GC content: 65.07

Gene sequence:

>2697_bases
ATGTCCGCTGTACCGAATGAAGTGATGAAGTATGTCGCCGCCGAGCGTGACGACGACCCGCAGGAAACCGTTGAATGGCT
CGAGGCGCTGGACGGCGTGATCTCCTCCGTGGGTACCGGCCGCGCGCACTACCTGATCGAAAAGCAGATCGAATTCGCAC
GCATGCACGGCGAACATCTGCCGTTTTCCGCGAACACCCCGTACATCAACACGATTCCGGTCGAAGCCCAGGCCAAGATT
CCGGGCGACCAGGACATCGAGCACCGCATCCGCTCGTACACGCGCTGGAACGCGCTCGCGATGGTGCTGCGCGCCGGCAA
GGACACGAACGTCGGCGGCCACATCGCGTCGTTCGCATCGGCCGCGACGCTGTACGACGTCGGCTACAACCATTTCTGGC
ACGCACCGTCCGACCAGCACGGCGGCGATCTCGTGTTCGTGCAGGGCCACTCGTCGCCGGGCGTGTACTCGCGCGCGTTC
CTGCTCGGCCGCCTGACCGAGGAGCAGCTTGACAACTTCCGCCAGGAAGTCGGCGGCAACGGCATCTCGTCGTACCCGCA
CCCGTGGCTGATGCCGGACTTCTGGCAGTTCCCGACCGTCTCGATGGGCCTCGGTCCGATCATGGCGATCTACCAGGCGC
GCTTCATGAAGTACCTCGAGGCGCGCGGCATCGCGAAGACGGAAGGCCGCAAGGTGTGGGCGTTCCTCGGCGACGGCGAG
ACCGACGAACCGGAATCGCTCGGCGCGATCGGGATGGCGAGCCGCGAGAAGCTCGACAACCTCGTGTTCGTGATCAACTG
CAACCTGCAGCGTCTCGACGGCCCGGTGCGCGGCAACGGCAAGATCATCCAGGAACTGGAATCGGAATTCCGCGGCGCCG
GCTGGAACGTCATCAAGGTGATCTGGGGCAGCCGCTGGGATGCGCTGTTCGCGCGCGACAAGACGGGCGCGCTGATGCGC
CGGATGATGGAAGTCGTCGACGGCGAATACCAGACCTACAAGTCGGAGTCGGGCGCGTTCGTCCGCGAGCACTTCTTCAA
CACGCCGGAGCTGAAGGCGCTCGTCGCCGACTGGTCCGACGACGACATCTGGAACCTGAACCGCGGCGGCCACGATCCGC
ACAAGATCTACGCGGCGTTCCATGAAGCGACGCACACGAAGGGCGCGCCGACCGTCATCCTCGCGAAGACCATCAAGGGC
TACGGGATGGGCGAGTCCGGTCAGGCGATGAACATCACGCACCAGCAGAAGAAGCTGCCGGTCGAGCAACTGAAGAAGTT
CCGCGATCAGTTCCGCCTGCCGATCACCGACGAGCAGATCGCCGACGTGCCGTACCTGAAGTTCGAGGAAGGCTCGAAGG
AACTCGAATACATGCGCCAGAAGCGCATGGACCTCGGCGGCTACCTGCCGCAGCGCCGCCAGAAGGCGGCATCGCTGCCG
GTGCCGGCGCTCGACGCGTTCGAGCCGCTGCTCAAGGGCACGGGCGAGGGCCGCGAGATCTCGACGACGATGGCGTTCGT
GCGGATCCTGAACATCCTGCTGAAGGACAAGGCGCTCGGCAAGCGCGTGGTGCCGATCGTCCCGGACGAGTCGCGCACGT
TCGGCATGGAAGGCCTGTTCCGCCAGATCGGCATCTGGAACCAGGAAGGCCAGAAGTACGTGCCGGAAGATTCCGATCAG
CTGATGTTCTACAAGGAATCGCAGACCGGCCAGATCCTGCAGGAAGGCATCAACGAAGCGGGCGGCATGTGCGACTGGAT
CGCGGCGGCGACGTCGTACTCGACGCACGGCGAGATCATGGTGCCGTTCTACATCTTCTACTCGATGTTCGGCTTCCAGC
GGATCGGCGATCTGGCCTGGGCGGCCGGCGACATGCGTTCGCGCGGCTTCCTGCTCGGCGGCACCGCGGGCCGCACGACG
CTGAACGGCGAAGGTCTGCAGCACGAAGACGGCCACTCGCTGCTGTGGGCGGCATCGGTGCCGAACTGCGTCAGCTACGA
CCCGACGTTCGGCTACGAGCTCGCGGTCATCATCCAGGACGGCCTGCGCCGGATGGTGCAGGACCAGGAAGACGTGTACT
ACTACATCACGGTGATGAACGAGAACTACGAGCACCCGGCGATTCCGCAGGGCGAGCACGTGGCGGCCGACATCATCAAG
GGCATGTACGCGTTCCGCAAGGCGGACGCCAACGCGAAGGCGCCGCGCGTGCAGCTGCTCGGCGCGGGCACGATCTTCAA
CGAAGTGATCGCTGCCGCCGATCTGCTGAAGAAGGACTGGGGCGTCGCCGCCGATCTGTGGAGCGTGCCGAGCTTCACCG
AGCTCGCGCGCGAAGGCCACGACGTCGAGCGCTGGAACCTGCTGCACCCGACCGAGGAGCGCCGCCTGTCGCACGTGCAG
AAGTGCCTGAAGGACACGCAGGGCCCGGTCATCGCCTCGACCGACTACGTGCGCGCGCTGGCCGACCAGATCCGCGGCCA
GATCGATCGCCGCTACGTCGTGCTCGGCACCGACGGCTACGGCCGTTCGGATACGCGTGAGAAGCTGCGTCACTTCTTCG
AAGTCGACCGCTACTGGGTGACGGTGGCCGCGCTGAACGCGCTGGCCGACGAGGGCACGATCGATCGCAAGATCGTCGCC
GACGCGATCGCGAAGTACAACCTCGATCCGTCGAAGCCGAACCCGATGACCGTTTAA

Upstream 100 bases:

>100_bases
CCGGCACGCTCATTACAATCCGCTGAGCTTGCCCGCAGCCGGCCGCGCCGCGTCGTCTGCACGAGAGCGATCCTCACATT
CCAGGACCCAGGAGACGAGA

Downstream 100 bases:

>100_bases
CGACACGCGCCGCGTGATGCCGCGCGCCGCCTCGCGGGGAGGCGCGCGGTCCTGGAGACACAGACAGATGAGTCAAGCGA
TCGAAGTGAAGGTGCCGGAT

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MSAVPNEVMKYVAAERDDDPQETVEWLEALDGVISSVGTGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAPSDQHGGDLVFVQGHSSPGVYSRAF
LLGRLTEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGIAKTEGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMR
RMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEATHTKGAPTVILAKTIKG
YGMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPQRRQKAASLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
GMYAFRKADANAKAPRVQLLGAGTIFNEVIAAADLLKKDWGVAADLWSVPSFTELAREGHDVERWNLLHPTEERRLSHVQ
KCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGYGRSDTREKLRHFFEVDRYWVTVAALNALADEGTIDRKIVA
DAIAKYNLDPSKPNPMTV

Sequences:

>Translated_898_residues
MSAVPNEVMKYVAAERDDDPQETVEWLEALDGVISSVGTGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAPSDQHGGDLVFVQGHSSPGVYSRAF
LLGRLTEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGIAKTEGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMR
RMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEATHTKGAPTVILAKTIKG
YGMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPQRRQKAASLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
GMYAFRKADANAKAPRVQLLGAGTIFNEVIAAADLLKKDWGVAADLWSVPSFTELAREGHDVERWNLLHPTEERRLSHVQ
KCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGYGRSDTREKLRHFFEVDRYWVTVAALNALADEGTIDRKIVA
DAIAKYNLDPSKPNPMTV
>Mature_897_residues
SAVPNEVMKYVAAERDDDPQETVEWLEALDGVISSVGTGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKIP
GDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAPSDQHGGDLVFVQGHSSPGVYSRAFL
LGRLTEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGIAKTEGRKVWAFLGDGET
DEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMRR
MMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEATHTKGAPTVILAKTIKGY
GMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPQRRQKAASLPV
PALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQL
MFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIKG
MYAFRKADANAKAPRVQLLGAGTIFNEVIAAADLLKKDWGVAADLWSVPSFTELAREGHDVERWNLLHPTEERRLSHVQK
CLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGYGRSDTREKLRHFFEVDRYWVTVAALNALADEGTIDRKIVAD
AIAKYNLDPSKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=59.774011299435, Blast_Score=1088, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100785; Mature: 100654

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPNEVMKYVAAERDDDPQETVEWLEALDGVISSVGTGRAHYLIEKQIEFARMHGEHL
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAPSDQHGGDLVFVQGHSSPGVYSRAFLLGRLTEEQLDNFRQEVGGN
HHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGIAKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKTGALMRRMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSD
EECCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHHEEECCCC
DDIWNLNRGGHDPHKIYAAFHEATHTKGAPTVILAKTIKGYGMGESGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCCCEECCCHHHHCCC
VEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPQRRQKAASLP
HHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKADANAKAPRVQLLGAGTIFNEVIAAADLLKKDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHCCC
DVERWNLLHPTEERRLSHVQKCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGY
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTREKLRHFFEVDRYWVTVAALNALADEGTIDRKIVADAIAKYNLDPSKPNPMTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPNEVMKYVAAERDDDPQETVEWLEALDGVISSVGTGRAHYLIEKQIEFARMHGEHL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAPSDQHGGDLVFVQGHSSPGVYSRAFLLGRLTEEQLDNFRQEVGGN
HHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGIAKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKTGALMRRMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSD
EECCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHHEEECCCC
DDIWNLNRGGHDPHKIYAAFHEATHTKGAPTVILAKTIKGYGMGESGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCCCEECCCHHHHCCC
VEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPQRRQKAASLP
HHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKADANAKAPRVQLLGAGTIFNEVIAAADLLKKDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHCCC
DVERWNLLHPTEERRLSHVQKCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGY
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTREKLRHFFEVDRYWVTVAALNALADEGTIDRKIVADAIAKYNLDPSKPNPMTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]