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The map label for this gene is appB [H]

Identifier: 160902776

GI number: 160902776

Start: 1426195

End: 1427244

Strand: Direct

Name: appB [H]

Synonym: Pmob_1330

Alternate gene names: 160902776

Gene position: 1426195-1427244 (Clockwise)

Preceding gene: 160902775

Following gene: 160902777

Centisome position: 65.74

GC content: 37.33

Gene sequence:

>1050_bases
ATGTATTGGAGATATGCTGTTCGAAGAATATTAATGGGTGTTGTTATTTACGTTGTGGTCATTTTCATTTATTCTGCCTT
GTTTAACACGGTGATGGATCAGACGTTAAATAGTCAAATAGTTGAACAAGTAAACGGTGAAATGATGAAAATGTCACAGG
TTGGAACAGATCCTGAATATTTGGTAGAATACAGAGAGAGGCGAATCAGTGAGCTTCGTCAATTGTATCACTTAGATGAT
CCCATACTTTCCAGGATTTTTTGGAGAGCTATCGATACGTTAACATTCAATTATGGGAACTCAACTGTAATGAGATCTTT
TGAAGGTGAAACAGACGTTATTAAAATAGTTCTAGAAAGAATTCCCAACACCTTGATGTTGTTTACTACTGCGATAATTA
TCGATATTTTTATAGGTGTATGGTTGGGTATAAGAAAAGCTCAGAAAGCTGGAAAGTTAATGGATAAGACTACTTCTATA
ATCACCATGGGGGTGTACGGTCTGCCATCTTGGTGGTTTGGAATGGTTATGATTATGTTGTTTGCGTTTGCAATACCTAT
TTTCCCATCAGGAGGTATGAACAGTGTCCCTCCTCCAACAACCTTTTTTGGAAGATTCCTTGATACTTTATACCATATGG
CTTTACCTGTAATTACTTTAGTGTTCATAGGTTTTTGGGGAAGGGCTTATTTAACAAGGAATATAGTTTTAGGAAATCTT
CAAGAAGATTTCATAATGTCCGCAAGGGCAAGAGGGATTCCTGAAAGGTCTGTTTTATATGGTCATGCTCTAAGAACCTC
TGCTCCTCCTATTTTAACAATGTCGCTTTTATCGTTGTTAGCTTCTTTTTCTGGTGCGTTGGTGTTTGAAGGTATATTTA
GTTGGCCTGGAATGGGTAACCTTTATTGGGCAGCGGTTCAGATGAACGATATCCCTGTTCTTTTGGGTAACCTTTCCATA
ACAACACTTATATACATTTCTGGTATCGTAGTTTTGGATTTGATATACGGCTTTTTAGACCCTAGAATAAAAGTTGGTGG
GAAAGCGTGA

Upstream 100 bases:

>100_bases
GTGTATTAATCTTCTAAAAAAGTCATTTTAGAGTTTAAGGGCTCCCTTATGGGAGCCTATTTTTAGAAAAGTTGAACTAT
ATACAGAGGTGATTAACCGT

Downstream 100 bases:

>100_bases
ATAAAACAAATCGTGTTGCCAAGCAATTAAAAGATTTTTGGGATGAGTTTAAGCAAGTTAAATTTGGTATAGCTGGTATA
ATTCTTTTAATCCTTTTTGT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MYWRYAVRRILMGVVIYVVVIFIYSALFNTVMDQTLNSQIVEQVNGEMMKMSQVGTDPEYLVEYRERRISELRQLYHLDD
PILSRIFWRAIDTLTFNYGNSTVMRSFEGETDVIKIVLERIPNTLMLFTTAIIIDIFIGVWLGIRKAQKAGKLMDKTTSI
ITMGVYGLPSWWFGMVMIMLFAFAIPIFPSGGMNSVPPPTTFFGRFLDTLYHMALPVITLVFIGFWGRAYLTRNIVLGNL
QEDFIMSARARGIPERSVLYGHALRTSAPPILTMSLLSLLASFSGALVFEGIFSWPGMGNLYWAAVQMNDIPVLLGNLSI
TTLIYISGIVVLDLIYGFLDPRIKVGGKA

Sequences:

>Translated_349_residues
MYWRYAVRRILMGVVIYVVVIFIYSALFNTVMDQTLNSQIVEQVNGEMMKMSQVGTDPEYLVEYRERRISELRQLYHLDD
PILSRIFWRAIDTLTFNYGNSTVMRSFEGETDVIKIVLERIPNTLMLFTTAIIIDIFIGVWLGIRKAQKAGKLMDKTTSI
ITMGVYGLPSWWFGMVMIMLFAFAIPIFPSGGMNSVPPPTTFFGRFLDTLYHMALPVITLVFIGFWGRAYLTRNIVLGNL
QEDFIMSARARGIPERSVLYGHALRTSAPPILTMSLLSLLASFSGALVFEGIFSWPGMGNLYWAAVQMNDIPVLLGNLSI
TTLIYISGIVVLDLIYGFLDPRIKVGGKA
>Mature_349_residues
MYWRYAVRRILMGVVIYVVVIFIYSALFNTVMDQTLNSQIVEQVNGEMMKMSQVGTDPEYLVEYRERRISELRQLYHLDD
PILSRIFWRAIDTLTFNYGNSTVMRSFEGETDVIKIVLERIPNTLMLFTTAIIIDIFIGVWLGIRKAQKAGKLMDKTTSI
ITMGVYGLPSWWFGMVMIMLFAFAIPIFPSGGMNSVPPPTTFFGRFLDTLYHMALPVITLVFIGFWGRAYLTRNIVLGNL
QEDFIMSARARGIPERSVLYGHALRTSAPPILTMSLLSLLASFSGALVFEGIFSWPGMGNLYWAAVQMNDIPVLLGNLSI
TTLIYISGIVVLDLIYGFLDPRIKVGGKA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788504, Length=372, Percent_Identity=27.9569892473118, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789965, Length=297, Percent_Identity=30.976430976431, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787053, Length=292, Percent_Identity=28.0821917808219, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787761, Length=294, Percent_Identity=30.2721088435374, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787497, Length=276, Percent_Identity=25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789888, Length=301, Percent_Identity=23.9202657807309, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39470; Mature: 39470

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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EEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]